GlyCosmos Portal

Submissions

ATP binding cassette subfamily A member 1

Summary

Gene Symbol

ABCA1

Organism

Homo sapiens (human)

External Links

NCBI Gene

PubChem

Alliance of Genome Resources

HGNC:29

Annotation

Keyword

3D-structure
ATP-binding
Atherosclerosis
Cell membrane
Cholesterol metabolism
Disease variant
Disulfide bond
Endosome
Glycoprotein
Palmitate
Phosphoprotein
Reference proteome
Repeat
Translocase
Transmembrane helix
Transport

Proteins

Displaying **all 3** entries
UniProt	Protein Name
O95477	ATP-binding cassette sub-family A member 1 ATP-binding cassette transporter 1 Cholesterol efflux regulatory protein
B7XCW9
B2RUU2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 37 in total

1

2

3

4

5

…

Next ›

Last »
GO Term	Evidence Code	PMID
protein transmembrane transport	ISS	29937375
cholesterol metabolic process	IDA	14747463
response to vitamin B3	IEA
positive regulation of cholesterol efflux	IEA
reverse cholesterol transport	IMP	10431236

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

lipoprotein metabolic process [inference]

lipoprotein biosynthetic process

organonitrogen compound biosynthetic process [inference]

lipoprotein biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

lipoprotein biosynthetic process

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

lipoprotein biosynthetic process

organonitrogen compound biosynthetic process [inference]

lipoprotein biosynthetic process

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

lipoprotein biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

sterol metabolic process [inference]

cholesterol metabolic process

protein metabolic process [inference]

lipoprotein metabolic process [inference]

lipoprotein biosynthetic process

small molecule metabolic process [inference]

alcohol metabolic process [inference]

secondary alcohol metabolic process [inference]

cholesterol metabolic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

sterol metabolic process [inference]

cholesterol metabolic process

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

lipoprotein biosynthetic process

protein metabolic process [inference]

lipoprotein metabolic process [inference]

lipoprotein biosynthetic process

organic cyclic compound metabolic process [inference]

steroid metabolic process [inference]

sterol metabolic process [inference]

cholesterol metabolic process

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

lipoprotein metabolic process [inference]

lipoprotein biosynthetic process

organonitrogen compound biosynthetic process [inference]

lipoprotein biosynthetic process

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

lipoprotein biosynthetic process

organonitrogen compound biosynthetic process [inference]

lipoprotein biosynthetic process

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

secondary alcohol metabolic process [inference]

cholesterol metabolic process

sterol metabolic process [inference]

cholesterol metabolic process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

apolipoprotein A-I-mediated signaling pathway

G protein-coupled receptor signaling pathway

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating G protein-coupled receptor signaling pathway

vesicle-mediated transport [inference]

endosomal transport

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

lipoprotein biosynthetic process

cellular localization [inference]

intracellular transport [inference]

endosomal transport

intracellular lipid transport [inference]

intracellular sterol transport [inference]

intracellular cholesterol transport

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

establishment of protein localization to extracellular region [inference]

protein secretion

protein localization to extracellular region [inference]

establishment of protein localization to extracellular region [inference]

protein secretion

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus

cellular response to lipid [inference]

cellular response to sterol [inference]

cellular response to cholesterol

cellular response to organic cyclic compound [inference]

cellular response to sterol [inference]

cellular response to cholesterol

cellular response to alcohol [inference]

cellular response to cholesterol

cellular response to xenobiotic stimulus

cellular response to oxygen-containing compound [inference]

cellular response to sterol [inference]

cellular response to cholesterol

cellular response to alcohol [inference]

cellular response to cholesterol

cellular response to biotic stimulus [inference]

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

cellular response to lipoprotein particle stimulus [inference]

cellular response to low-density lipoprotein particle stimulus

transmembrane transport [inference]

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

vacuole organization [inference]

lytic vacuole organization [inference]

lysosome organization

vesicle organization [inference]

secretory granule organization [inference]

platelet dense granule organization

cellular component assembly [inference]

protein-containing complex assembly [inference]

protein-lipid complex assembly [inference]

plasma lipoprotein particle assembly [inference]

high-density lipoprotein particle assembly

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

protein-lipid complex assembly [inference]

plasma lipoprotein particle assembly [inference]

high-density lipoprotein particle assembly

protein-lipid complex organization [inference]

protein-lipid complex assembly [inference]

plasma lipoprotein particle assembly [inference]

high-density lipoprotein particle assembly

plasma lipoprotein particle organization [inference]

plasma lipoprotein particle assembly [inference]

high-density lipoprotein particle assembly

membrane organization [inference]

membrane invagination [inference]

plasma membrane invagination [inference]

phagocytosis, engulfment

regulation of membrane lipid distribution [inference]

lipid translocation [inference]

export from cell [inference]

secretion by cell [inference]

export across plasma membrane

multicellular organismal process [inference]

plasma lipoprotein particle organization [inference]

plasma lipoprotein particle assembly [inference]

high-density lipoprotein particle assembly

homeostatic process [inference]

chemical homeostasis [inference]

lipid homeostasis [inference]

phospholipid homeostasis

sterol homeostasis [inference]

cholesterol homeostasis

response to stimulus [inference]

response to stress [inference]

response to fluid shear stress [inference]

response to laminar fluid shear stress

response to external stimulus [inference]

response to extracellular stimulus [inference]

response to nutrient levels [inference]

response to nutrient [inference]

response to vitamin [inference]

response to vitamin B3

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

cellular response to biotic stimulus [inference]

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

response to endogenous stimulus [inference]

response to lipoprotein particle [inference]

cellular response to low-density lipoprotein particle stimulus

response to chemical [inference]

response to nutrient [inference]

response to vitamin [inference]

response to vitamin B3

response to xenobiotic stimulus [inference]

cellular response to xenobiotic stimulus

response to organic substance [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

response to organonitrogen compound [inference]

response to lipoprotein particle [inference]

cellular response to low-density lipoprotein particle stimulus

response to organic cyclic compound [inference]

response to sterol [inference]

cellular response to sterol [inference]

cellular response to cholesterol

response to cholesterol [inference]

cellular response to cholesterol

cellular response to organic cyclic compound [inference]

cellular response to sterol [inference]

cellular response to cholesterol

response to lipid [inference]

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

response to retinoic acid [inference]

cellular response to retinoic acid

response to sterol [inference]

cellular response to sterol [inference]

cellular response to cholesterol

response to cholesterol [inference]

cellular response to cholesterol

cellular response to lipid [inference]

cellular response to sterol [inference]

cellular response to cholesterol

response to cytokine [inference]

cellular response to cytokine stimulus

cellular response to organic substance [inference]

cellular response to cytokine stimulus

cellular response to lipid [inference]

cellular response to sterol [inference]

cellular response to cholesterol

cellular response to organic cyclic compound [inference]

cellular response to sterol [inference]

cellular response to cholesterol

cellular response to alcohol [inference]

cellular response to cholesterol

response to alcohol [inference]

response to cholesterol [inference]

cellular response to cholesterol

cellular response to alcohol [inference]

cellular response to cholesterol

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus

cellular response to lipid [inference]

cellular response to sterol [inference]

cellular response to cholesterol

cellular response to organic cyclic compound [inference]

cellular response to sterol [inference]

cellular response to cholesterol

cellular response to alcohol [inference]

cellular response to cholesterol

cellular response to xenobiotic stimulus

cellular response to oxygen-containing compound [inference]

cellular response to sterol [inference]

cellular response to cholesterol

cellular response to alcohol [inference]

cellular response to cholesterol

response to nitrogen compound [inference]

response to organonitrogen compound [inference]

response to lipoprotein particle [inference]

cellular response to low-density lipoprotein particle stimulus

response to oxygen-containing compound [inference]

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

response to retinoic acid [inference]

cellular response to retinoic acid

response to sterol [inference]

cellular response to sterol [inference]

cellular response to cholesterol

response to cholesterol [inference]

cellular response to cholesterol

response to alcohol [inference]

response to cholesterol [inference]

cellular response to cholesterol

cellular response to alcohol [inference]

cellular response to cholesterol

cellular response to oxygen-containing compound [inference]

cellular response to sterol [inference]

cellular response to cholesterol

cellular response to alcohol [inference]

cellular response to cholesterol

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus

cellular response to lipid [inference]

cellular response to sterol [inference]

cellular response to cholesterol

cellular response to organic cyclic compound [inference]

cellular response to sterol [inference]

cellular response to cholesterol

cellular response to alcohol [inference]

cellular response to cholesterol

cellular response to xenobiotic stimulus

cellular response to oxygen-containing compound [inference]

cellular response to sterol [inference]

cellular response to cholesterol

cellular response to alcohol [inference]

cellular response to cholesterol

cellular response to biotic stimulus [inference]

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

cellular response to lipoprotein particle stimulus [inference]

cellular response to low-density lipoprotein particle stimulus

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

establishment of protein localization to extracellular region [inference]

protein secretion

protein localization to extracellular region [inference]

establishment of protein localization to extracellular region [inference]

protein secretion

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

endosomal transport

secretion [inference]

peptide secretion

secretion by cell [inference]

intracellular transport [inference]

endosomal transport

intracellular lipid transport [inference]

intracellular sterol transport [inference]

intracellular cholesterol transport

transmembrane transport [inference]

organic substance transport [inference]

lipid transport [inference]

phospholipid transport [inference]

sterol transport [inference]

cholesterol transport [inference]

intracellular sterol transport [inference]

intracellular cholesterol transport

intracellular lipid transport [inference]

intracellular sterol transport [inference]

intracellular cholesterol transport

lipid translocation [inference]

protein transport [inference]

organophosphate ester transport [inference]

phospholipid transport [inference]

peptide transport [inference]

peptide secretion

organic hydroxy compound transport [inference]

sterol transport [inference]

cholesterol transport [inference]

intracellular sterol transport [inference]

intracellular cholesterol transport

nitrogen compound transport [inference]

protein transport [inference]

amide transport [inference]

peptide transport [inference]

peptide secretion

sphingolipid translocation

export from cell [inference]

secretion by cell [inference]

export across plasma membrane

establishment of protein localization [inference]

protein transport [inference]

establishment of protein localization to extracellular region [inference]

protein secretion

establishment of localization in cell [inference]

intracellular transport [inference]

endosomal transport

intracellular lipid transport [inference]

intracellular sterol transport [inference]

intracellular cholesterol transport

cellular localization [inference]

intracellular transport [inference]

endosomal transport

intracellular lipid transport [inference]

intracellular sterol transport [inference]

intracellular cholesterol transport

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

establishment of protein localization to extracellular region [inference]

protein secretion

protein localization to extracellular region [inference]

establishment of protein localization to extracellular region [inference]

protein secretion

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction [inference]

regulation of Ras protein signal transduction [inference]

regulation of Rho protein signal transduction [inference]

regulation of Cdc42 protein signal transduction

regulation of localization [inference]

regulation of lipid storage [inference]

regulation of cholesterol storage [inference]

negative regulation of cholesterol storage

negative regulation of lipid storage [inference]

negative regulation of cholesterol storage

regulation of transport [inference]

regulation of lipid transport [inference]

positive regulation of lipid transport [inference]

positive regulation of sterol transport [inference]

positive regulation of cholesterol transport [inference]

positive regulation of cholesterol efflux

regulation of sterol transport [inference]

positive regulation of sterol transport [inference]

positive regulation of cholesterol transport [inference]

positive regulation of cholesterol efflux

regulation of cholesterol transport [inference]

regulation of cholesterol efflux [inference]

positive regulation of cholesterol efflux

positive regulation of cholesterol transport [inference]

positive regulation of cholesterol efflux

positive regulation of transport [inference]

positive regulation of lipid transport [inference]

positive regulation of sterol transport [inference]

positive regulation of cholesterol transport [inference]

positive regulation of cholesterol efflux

regulation of lipid localization [inference]

regulation of lipid transport [inference]

positive regulation of lipid transport [inference]

positive regulation of sterol transport [inference]

positive regulation of cholesterol transport [inference]

positive regulation of cholesterol efflux

regulation of sterol transport [inference]

positive regulation of sterol transport [inference]

positive regulation of cholesterol transport [inference]

positive regulation of cholesterol efflux

regulation of cholesterol transport [inference]

regulation of cholesterol efflux [inference]

positive regulation of cholesterol efflux

positive regulation of cholesterol transport [inference]

positive regulation of cholesterol efflux

negative regulation of lipid localization [inference]

negative regulation of lipid storage [inference]

negative regulation of cholesterol storage

positive regulation of lipid localization [inference]

positive regulation of lipid transport [inference]

positive regulation of sterol transport [inference]

positive regulation of cholesterol transport [inference]

positive regulation of cholesterol efflux

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of high-density lipoprotein particle assembly

positive regulation of cellular component organization [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of high-density lipoprotein particle assembly

positive regulation of transport [inference]

positive regulation of lipid transport [inference]

positive regulation of sterol transport [inference]

positive regulation of cholesterol transport [inference]

positive regulation of cholesterol efflux

positive regulation of multicellular organismal process [inference]

positive regulation of high-density lipoprotein particle assembly

positive regulation of lipid localization [inference]

positive regulation of lipid transport [inference]

positive regulation of sterol transport [inference]

positive regulation of cholesterol transport [inference]

positive regulation of cholesterol efflux

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cell differentiation [inference]

negative regulation of macrophage derived foam cell differentiation

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of macrophage derived foam cell differentiation

negative regulation of lipid localization [inference]

negative regulation of lipid storage [inference]

negative regulation of cholesterol storage

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction [inference]

regulation of Ras protein signal transduction [inference]

regulation of Rho protein signal transduction [inference]

regulation of Cdc42 protein signal transduction

regulation of developmental process [inference]

regulation of cell differentiation [inference]

regulation of macrophage derived foam cell differentiation [inference]

negative regulation of macrophage derived foam cell differentiation

negative regulation of cell differentiation [inference]

negative regulation of macrophage derived foam cell differentiation

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of macrophage derived foam cell differentiation

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

apolipoprotein A-I-mediated signaling pathway

G protein-coupled receptor signaling pathway

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating G protein-coupled receptor signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction [inference]

regulation of Ras protein signal transduction [inference]

regulation of Rho protein signal transduction [inference]

regulation of Cdc42 protein signal transduction

regulation of cellular component biogenesis [inference]

regulation of protein-containing complex assembly [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of high-density lipoprotein particle assembly

regulation of high-density lipoprotein particle assembly

positive regulation of high-density lipoprotein particle assembly

positive regulation of cellular component biogenesis [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of high-density lipoprotein particle assembly

regulation of cell differentiation [inference]

regulation of macrophage derived foam cell differentiation [inference]

negative regulation of macrophage derived foam cell differentiation

negative regulation of cell differentiation [inference]

negative regulation of macrophage derived foam cell differentiation

positive regulation of cellular process [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of high-density lipoprotein particle assembly

positive regulation of cellular component organization [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of high-density lipoprotein particle assembly

negative regulation of cellular process [inference]

negative regulation of cell differentiation [inference]

negative regulation of macrophage derived foam cell differentiation

regulation of cellular component organization [inference]

regulation of protein-containing complex assembly [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of high-density lipoprotein particle assembly

regulation of high-density lipoprotein particle assembly

positive regulation of high-density lipoprotein particle assembly

positive regulation of cellular component organization [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of high-density lipoprotein particle assembly

regulation of multicellular organismal process [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of high-density lipoprotein particle assembly

regulation of high-density lipoprotein particle assembly

positive regulation of high-density lipoprotein particle assembly

regulation of biological quality [inference]

regulation of membrane lipid distribution [inference]

lipid translocation [inference]

Displaying entries **1 - 5** of 12 in total

1

2

3

Next ›

Last »
GO Term	Evidence Code	PMID
external side of plasma membrane	IEA
Golgi apparatus	IEA
endocytic vesicle	IDA	14747463
endoplasmic reticulum membrane	TAS
intracellular membrane-bounded organelle	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

organelle membrane [inference]

endoplasmic reticulum membrane

plasma membrane region [inference]

basolateral plasma membrane

membrane microdomain [inference]

membrane raft

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle

cytoplasmic vesicle [inference]

endosome

endocytic vesicle

phagocytic vesicle

intracellular membrane-bounded organelle

Golgi apparatus

intracellular vesicle

cytoplasmic vesicle [inference]

endosome

endocytic vesicle

phagocytic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle

Golgi apparatus

intracellular vesicle

cytoplasmic vesicle [inference]

endosome

endocytic vesicle

phagocytic vesicle

perinuclear region of cytoplasm

side of membrane [inference]

external side of plasma membrane

Displaying entries **1 - 5** of 22 in total

1

2

3

4

5

Next ›

Last »
GO Term	Evidence Code	PMID
protein binding	IPI	12084722 14754908 15469992 16192269 16443932 23931754 25170080 30458687
ABC-type transporter activity	IEA
cholesterol transfer activity	IDA	12084722
apolipoprotein A-I binding	IPI	11162594 16443932
signaling receptor binding	IPI	23931754

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

ATP hydrolysis activity

transporter activity [inference]

lipid transporter activity [inference]

phospholipid transporter activity

phosphatidylcholine transporter activity [inference]

phosphatidylcholine floppase activity

phosphatidylserine floppase activity

sterol transporter activity [inference]

sterol transfer activity [inference]

cholesterol transfer activity

sphingolipid transporter activity [inference]

sphingolipid floppase activity

lipid transfer activity [inference]

sterol transfer activity [inference]

cholesterol transfer activity

intramembrane lipid transporter activity [inference]

ATPase-coupled intramembrane lipid transporter activity [inference]

floppase activity

transmembrane transporter activity [inference]

active transmembrane transporter activity [inference]

primary active transmembrane transporter activity [inference]

ATPase-coupled transmembrane transporter activity

ABC-type transporter activity

macromolecule transmembrane transporter activity [inference]

protein transmembrane transporter activity

protein transporter activity [inference]

protein transmembrane transporter activity

binding [inference]

protein binding

SNARE binding [inference]

syntaxin binding

signaling receptor binding

enzyme binding [inference]

GTPase binding [inference]

small GTPase binding

ATPase binding

apolipoprotein binding

apolipoprotein A-I binding

lipid binding [inference]

steroid binding [inference]

sterol binding [inference]

cholesterol binding

phospholipid binding [inference]

phosphatidylcholine binding

small molecule binding [inference]

alcohol binding [inference]

cholesterol binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

cation binding [inference]

phosphatidylcholine binding

protein-containing complex binding [inference]

protein-lipid complex binding [inference]

lipoprotein particle binding [inference]

high-density lipoprotein particle binding

organic cyclic compound binding [inference]

steroid binding [inference]

sterol binding [inference]

cholesterol binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

cargo receptor activity [inference]

apolipoprotein receptor activity [inference]

apolipoprotein A-I receptor activity

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

apolipoprotein A-I receptor activity

ATP-dependent activity [inference]

ATPase-coupled transmembrane transporter activity

ABC-type transporter activity

ATPase-coupled intramembrane lipid transporter activity [inference]

floppase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

ATP-binding cassette, sub-family A

Functional Category

K: Transcription
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
ABC-type transporter activity
ATP binding
lipid transporter activity
nucleotide binding

Displaying **all 6** entries
InterPro
AAA+ ATPase domain
ABC transporter A
ABC transporter-like, ATP-binding domain
ABC transporter-like, conserved site
ABC-2 type transporter, transmembrane domain
P-loop containing nucleoside triphosphate hydrolase

Disease

Disease Ontology

Displaying entries **1 - 10** of 16 in total

1

2

Next ›

Last »
DO ID	Disease Name	Source
DOID:0080957	primary hypoalphalipoproteinemia 1	Alliance of Genome Resources
DOID:10230	aortic atherosclerosis	Alliance of Genome Resources
DOID:10652	Alzheimer's disease	Alliance of Genome Resources
DOID:10787	premature menopause	Alliance of Genome Resources
DOID:10976	membranous glomerulonephritis	Alliance of Genome Resources
DOID:1168	familial hyperlipidemia	Alliance of Genome Resources
DOID:12236	primary biliary cholangitis	Alliance of Genome Resources
DOID:13619	extrahepatic cholestasis	Alliance of Genome Resources
DOID:1387	hypolipoproteinemia	Alliance of Genome Resources
DOID:1388	Tangier disease	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of **114** in total

1

2

3

4

5

…

Next ›

Last »
Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Mus musculus	11303		MGI:99607	MOUSE43128
Caenorhabditis elegans	171782		WB:WBGene00000020
Rattus norvegicus	313210		RGD:631344	RATNO33465
Pan troglodytes	464630	9598_0:0029f5		PANTR44511
Canis lupus familiaris	481651			CANLF02395
Bos taurus	535379			BOVIN35041
Danio rerio	558924		ZFIN:ZDB-GENE-031006-12	DANRE16707
Macaca mulatta	716146			MACMU11931
Monodelphis domestica	100013781			MONDO29503
Ornithorhynchus anatinus	100075984			ORNAN32473

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements