endothelin 1

Summary
Gene Symbol
  • EDN1
Organism
Homo sapiens (human)
NCBI Gene
1906
PubChem
1906
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • Cleavage on pair of basic residues
  • Direct protein sequencing
  • Disease variant
  • Disulfide bond
  • Reference proteome
  • Secreted
  • Signal
  • Vasoconstrictor
Proteins
Displaying all 2 entries
UniProt Protein Name
P05305
  • Preproendothelin-1
Q6FH53
Gene Ontology (GO)
GO Hierarchy
OrthoDB (Group)
Group level
Eukaryota
Group Name
Endothelin
Functional Category
  • M: Cell wall/membrane/envelope biogenesis
  • O: Posttranslational modification, protein turnover, chaperones
  • T: Signal transduction mechanisms
Disease
Disease Ontology
Displaying entries 1 - 10 of 13 in total
DO ID Disease Name Source
DOID:0050848 obstructive sleep apnea
DOID:10230 aortic atherosclerosis
DOID:10763 hypertension
DOID:1891 optic nerve disease
DOID:2799 bronchiolitis obliterans
DOID:2841 asthma
DOID:3083 chronic obstructive pulmonary disease
DOID:3393 coronary artery disease
DOID:4248 coronary stenosis
DOID:6000 congestive heart failure

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025