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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Gamma-aminobutyric acid type B receptor subunit 2
Summary
- Gene Symbol
-
- gbb-2
- Organism
- Caenorhabditis elegans
Annotation
- Keyword
-
- Cell membrane
- G-protein coupled receptor
- Glycoprotein
- Reference proteome
- Signal
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| G5ECB2 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| response to xenobiotic stimulus | ||
| regulation of locomotion |
|
|
| G protein-coupled receptor signaling pathway | ||
| gamma-aminobutyric acid signaling pathway | ||
| negative regulation of synaptic transmission, cholinergic |
| GO Term | Evidence Code | PMID |
|---|---|---|
| membrane | ||
| G protein-coupled receptor heterodimeric complex | ||
| plasma membrane | ||
| G protein-coupled GABA receptor complex |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| G protein-coupled GABA receptor activity | ||
| G protein-coupled receptor activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- receptor
- Functional Category
-
- E: Amino acid transport and metabolism
- M: Cell wall/membrane/envelope biogenesis
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| G protein-coupled GABA receptor activity |
| gamma-aminobutyric acid signaling pathway |
| InterPro |
|---|
| GPCR family 3, C-terminal |
| GPCR family 3, GABA-B receptor |
| Periplasmic binding protein-like I |
| Receptor, ligand binding region |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050742 | nicotine dependence | |
| DOID:0080291 | developmental and epileptic encephalopathy 59 | |
| DOID:1574 | alcohol use disorder |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 9568 | HGNC:4507 | |||
| 42561 | FB:FBgn0027575 | |||
| 83633 | RGD:619864 | |||
| 242425 | MGI:2386030 | |||
| 548761 | Xenbase:XB-GENE-5815161 | |||
| 560267 | ZFIN:ZDB-GENE-060503-620 | |||
| 6104505 | 6279_0:00169a | |||
| 9945009 | 7209_0:00080b | |||
| 25343197 | 51031_0:002639 | |||
| 36384958 | 34506_0:002a25 |
