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UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6

Summary

Gene Symbol

B3GNT6

Aliases

B3Gn-T6
core 3 synthase

Organism

Homo sapiens (human)

External Links

NCBI Gene

192134

GGDB ID

gg120

HGNC

24141

mRNA

NM_138706

map

11q13.4

Protein

NP_619651

OMIM

615315

KEGG Gene ID

hsa:192134

PubChem

192134

Alliance of Genome Resources

HGNC:24141

Annotation

Keyword

Alternative splicing
Glycoprotein
Glycosyltransferase
Golgi apparatus
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q6ZMB0	Core 3 synthase UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6
A8K9Q8

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
protein O-linked glycosylation	IBA
glycoprotein biosynthetic process	NAS	11821425
O-glycan processing	TAS
O-glycan processing, core 3	NAS	11821425
poly-N-acetyllactosamine biosynthetic process	IBA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan biosynthetic process [inference]

poly-N-acetyllactosamine biosynthetic process

poly-N-acetyllactosamine metabolic process [inference]

poly-N-acetyllactosamine biosynthetic process

protein metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

O-glycan processing

O-glycan processing, core 3

organonitrogen compound biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

poly-N-acetyllactosamine biosynthetic process

glycoprotein biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

poly-N-acetyllactosamine biosynthetic process

glycoprotein biosynthetic process

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

poly-N-acetyllactosamine biosynthetic process

glycoprotein biosynthetic process

carbohydrate derivative biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

poly-N-acetyllactosamine biosynthetic process

glycoprotein biosynthetic process

organonitrogen compound biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

poly-N-acetyllactosamine biosynthetic process

glycoprotein biosynthetic process

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

poly-N-acetyllactosamine biosynthetic process

glycoprotein biosynthetic process

primary metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

O-glycan processing

O-glycan processing, core 3

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein O-linked glycosylation

O-glycan processing

O-glycan processing, core 3

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan biosynthetic process [inference]

poly-N-acetyllactosamine biosynthetic process

poly-N-acetyllactosamine metabolic process [inference]

poly-N-acetyllactosamine biosynthetic process

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

poly-N-acetyllactosamine biosynthetic process

glycoprotein biosynthetic process

protein metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

O-glycan processing

O-glycan processing, core 3

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

O-glycan processing

O-glycan processing, core 3

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein O-linked glycosylation

O-glycan processing

O-glycan processing, core 3

carbohydrate derivative metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan biosynthetic process [inference]

poly-N-acetyllactosamine biosynthetic process

poly-N-acetyllactosamine metabolic process [inference]

poly-N-acetyllactosamine biosynthetic process

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process

carbohydrate derivative biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

poly-N-acetyllactosamine biosynthetic process

glycoprotein biosynthetic process

organonitrogen compound metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan biosynthetic process [inference]

poly-N-acetyllactosamine biosynthetic process

poly-N-acetyllactosamine metabolic process [inference]

poly-N-acetyllactosamine biosynthetic process

protein metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein biosynthetic process

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

O-glycan processing

O-glycan processing, core 3

organonitrogen compound biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

poly-N-acetyllactosamine biosynthetic process

glycoprotein biosynthetic process

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

poly-N-acetyllactosamine biosynthetic process

glycoprotein biosynthetic process

carbohydrate derivative biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

poly-N-acetyllactosamine biosynthetic process

glycoprotein biosynthetic process

organonitrogen compound biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

poly-N-acetyllactosamine biosynthetic process

glycoprotein biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

poly-N-acetyllactosamine biosynthetic process

glycoprotein biosynthetic process

Displaying **all 3** entries
GO Term	Evidence Code	PMID
Golgi membrane	TAS
Golgi membrane	IBA
membrane	NAS	11821425

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
UDP-glycosyltransferase activity	IBA
galactosyltransferase activity	IDA	11821425
galactosyltransferase activity	IBA
UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity	TAS
beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity	NAS	11821425

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

UDP-glycosyltransferase activity

acetylglucosaminyltransferase activity [inference]

UDP-galactosyltransferase activity [inference]

UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity

hexosyltransferase activity [inference]

acetylglucosaminyltransferase activity [inference]

galactosyltransferase activity

UDP-galactosyltransferase activity [inference]

UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity

beta-1,3-galactosyltransferase activity [inference]

UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity

catalytic activity, acting on a protein [inference]

catalytic activity, acting on a glycoprotein [inference]

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

galactosyltransferase

Functional Category

K: Transcription
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
hexosyltransferase activity
transferase activity

Displaying 1 entry
InterPro
Glycosyl transferase, family 31

GlycoGene Database (GGDB)

GGDB ID

gg120

Gene Symbol

B3GNT6

Reactions

Displaying 1 entry
Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
UDP-GlcNAc	G57321FI	[alpha]-pNP	G00035MO	[alpha]-pNP	11821425

Displaying **all 2** entries
Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
UDP-GlcNAc	G57321FI	O-glycan Synthesis	G00035MO	O-glycan Synthesis
UDP-GlcNAc	G57321FI	[alpha]-pNP	G00035MO	[alpha]-pNP	11821425

Displaying entries **1 - 5** of 22 in total

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Donor	Acceptor	Reducing terminal(Acceptor)	Reference
UDP-GlcNAc	G00041MO	[alpha]-pNP(core 6)	11821425
UDP-GlcNAc	G00035MO	[alpha]-pNP(core 3)	11821425
UDP-GlcNAc	G09546QO	[alpha]-pNP	11821425
UDP-GlcNAc	G00031MO	[alpha]-pNP(core 1)	11821425
UDP-GlcNAc	G61418DU	[beta]-pNP	11821425

Orthologous Gene

Displaying **all 2** entries
Species	Protein	mRNA
Rattus norvegicus	XP_217903	XM_217903
Mus musculus	XP_195661	XM_195661

KEGG BRITE Database

Orthology

K00739

Name

acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase [EC:2.4.1.147]

References

11821425

Reactions

Displaying 1 entry
KEGG Reaction	Enzyme	Acceptor	Product
R05909	2.4.1.147	G57321FI	G00035MO

Rhea

RHEA:46884

UDP-N-acetyl-α-D-glucosamine

H⁺ + UDP

Enzyme

2.4.1.147

PMID

RHEA:46880

UDP-N-acetyl-α-D-glucosamine

H⁺ + UDP

Enzyme

2.4.1.147

PMID

Ortholog

Displaying entries **1 - 10** of **143** in total

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Species	Gene ID	Alliance of Genome Resources
Caenorhabditis elegans	8705	WB:WBGene00000270
Drosophila melanogaster	8706	FB:FBgn0000221
Caenorhabditis elegans	8707	WB:WBGene00000270
Caenorhabditis elegans	8708	WB:WBGene00000270
Drosophila melanogaster	10317	FB:FBgn0000221
Xenopus tropicalis	10331	Xenbase:XB-GENE-996589
Drosophila melanogaster	10678	FB:FBgn0000221
Caenorhabditis elegans	26877	WB:WBGene00000270
Caenorhabditis elegans	26878	WB:WBGene00000270
Caenorhabditis elegans	26879	WB:WBGene00000270

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UniCarb-DR

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Other Information

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Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

GlycoGene Database (GGDB)

KEGG BRITE Database

International Collaboration

Acknowledgements