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glycoprotein m6b

Summary

Gene Symbol

Gpm6b

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

192179

PubChem

192179

Alliance of Genome Resources

RGD:620580

Annotation

Keyword

Cell membrane
Coiled coil
Developmental protein
Differentiation
Glycoprotein
Neurogenesis
Osteogenesis
Phosphoprotein
Protein transport
Reference proteome
Transmembrane helix

Proteins

Displaying **all 7** entries
UniProt	Protein Name
A0A8I6A9L3
A6K2I7
Q9JJK1	Rhombencephalic expression protein-29 kDa
A0A0G2JZB8
A6K2I4
A6K2J0
A6K2I6

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
axon development	IBA
negative regulation of protein localization to cell surface	ISO ISS
protein transport	IEA
central nervous system myelination	IBA
negative regulation of serotonin uptake	IBA ISO ISS

GO Hierarchy

biological process

cellular process [inference]

ensheathment of neurons [inference]

axon ensheathment [inference]

axon ensheathment in central nervous system [inference]

central nervous system myelination

myelination [inference]

central nervous system myelination

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

extracellular matrix assembly

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

axon development

extracellular structure organization [inference]

extracellular matrix organization [inference]

extracellular matrix assembly

external encapsulating structure organization [inference]

extracellular matrix organization [inference]

extracellular matrix assembly

multicellular organismal process [inference]

ossification

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport

establishment of localization [inference]

transport [inference]

organic substance transport [inference]

protein transport

nitrogen compound transport [inference]

protein transport

establishment of protein localization [inference]

protein transport

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

negative regulation of transport [inference]

negative regulation of neurotransmitter transport [inference]

negative regulation of neurotransmitter uptake [inference]

negative regulation of serotonin uptake

regulation of neurotransmitter transport [inference]

regulation of neurotransmitter uptake [inference]

negative regulation of neurotransmitter uptake [inference]

negative regulation of serotonin uptake

regulation of serotonin uptake [inference]

negative regulation of serotonin uptake

negative regulation of neurotransmitter transport [inference]

negative regulation of neurotransmitter uptake [inference]

negative regulation of serotonin uptake

regulation of cellular localization [inference]

regulation of protein localization [inference]

negative regulation of protein localization [inference]

negative regulation of protein localization to cell surface

regulation of protein localization to cell surface [inference]

negative regulation of protein localization to cell surface

positive regulation of biological process [inference]

positive regulation of developmental process [inference]

positive regulation of biomineral tissue development [inference]

positive regulation of bone mineralization

positive regulation of multicellular organismal process [inference]

positive regulation of ossification [inference]

positive regulation of bone mineralization

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of protein localization [inference]

negative regulation of protein localization to cell surface

negative regulation of transport [inference]

negative regulation of neurotransmitter transport [inference]

negative regulation of neurotransmitter uptake [inference]

negative regulation of serotonin uptake

regulation of developmental process [inference]

positive regulation of developmental process [inference]

positive regulation of biomineral tissue development [inference]

positive regulation of bone mineralization

regulation of multicellular organismal development [inference]

regulation of biomineral tissue development [inference]

regulation of bone mineralization [inference]

positive regulation of bone mineralization

positive regulation of biomineral tissue development [inference]

positive regulation of bone mineralization

regulation of cellular process [inference]

regulation of cell adhesion [inference]

regulation of cell-substrate adhesion [inference]

regulation of cell-matrix adhesion [inference]

regulation of focal adhesion assembly

regulation of actin filament-based process [inference]

regulation of actin cytoskeleton organization

regulation of cellular component biogenesis [inference]

regulation of cell junction assembly [inference]

regulation of cell-substrate junction assembly [inference]

regulation of focal adhesion assembly

negative regulation of cellular process [inference]

negative regulation of protein localization [inference]

negative regulation of protein localization to cell surface

regulation of cellular component organization [inference]

regulation of organelle organization [inference]

regulation of cytoskeleton organization [inference]

regulation of actin cytoskeleton organization

regulation of cell-substrate junction organization [inference]

regulation of cell-substrate junction assembly [inference]

regulation of focal adhesion assembly

regulation of cell junction assembly [inference]

regulation of cell-substrate junction assembly [inference]

regulation of focal adhesion assembly

regulation of cellular localization [inference]

regulation of protein localization [inference]

negative regulation of protein localization [inference]

negative regulation of protein localization to cell surface

regulation of protein localization to cell surface [inference]

negative regulation of protein localization to cell surface

regulation of multicellular organismal process [inference]

regulation of ossification [inference]

regulation of bone mineralization [inference]

positive regulation of bone mineralization

positive regulation of ossification [inference]

positive regulation of bone mineralization

positive regulation of multicellular organismal process [inference]

positive regulation of ossification [inference]

positive regulation of bone mineralization

regulation of multicellular organismal development [inference]

regulation of biomineral tissue development [inference]

regulation of bone mineralization [inference]

positive regulation of bone mineralization

positive regulation of biomineral tissue development [inference]

positive regulation of bone mineralization

Displaying **all 4** entries
GO Term	Evidence Code	PMID
membrane	IEA
plasma membrane	IBA ISO ISS
membrane raft	IBA ISO ISS
myelin sheath	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

membrane microdomain [inference]

membrane raft

myelin sheath

Displaying 1 entry
GO Term	Evidence Code	PMID
structural constituent of myelin sheath	IBA

GO Hierarchy

molecular function

structural molecule activity [inference]

structural constituent of myelin sheath

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

neuronal membrane glycoprotein M6-b

Functional Category

E: Amino acid transport and metabolism
J: Translation, ribosomal structure and biogenesis
M: Cell wall/membrane/envelope biogenesis

Displaying **all 2** entries
Gene Ontology
negative regulation of serotonin uptake
neuron projection development

Displaying **all 2** entries
InterPro
Myelin proteolipid protein PLP, conserved site
Myelin proteolipid protein PLP

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:1059	intellectual disability	Alliance of Genome Resources
DOID:1596	depressive disorder	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of **116** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	2824		HGNC:4461	HUMAN99806
Mus musculus	14758	10090_1:00576a	MGI:107672	MOUSE66332
Drosophila melanogaster	40383		FB:FBgn0037092
Caenorhabditis elegans	184437		WB:WBGene00017437
Danio rerio	368225		ZFIN:ZDB-GENE-030710-9
Pan troglodytes	465499			PANTR45520
Danio rerio	503756		ZFIN:ZDB-GENE-030710-10	DANRE45246
Bos taurus	516689			BOVIN37453
Xenopus tropicalis	549132		Xenbase:XB-GENE-942624
Macaca mulatta	711762			MACMU47695