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transient receptor potential cation channel, subfamily V, member 1

Summary

Gene Symbol

Trpv1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

193034

PubChem

193034

Alliance of Genome Resources

MGI:1341787

Annotation

Keyword

ANK repeat
ATP-binding
Alternative splicing
Calcium channel
Calmodulin-binding
Cell membrane
Cell projection
Glycoprotein
Ion channel
Metal-binding
Phosphoprotein
Postsynaptic cell membrane
Reference proteome
Repeat
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q3V318	Osm-9-like TRP channel 1 Vanilloid receptor 1
Q704Y3	Osm-9-like TRP channel 1 Vanilloid receptor 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **16 - 20** of 49 in total

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GO Term	Evidence Code	PMID
excitatory postsynaptic potential	IEA
response to peptide hormone	IEA
ion transmembrane transport	IEA IMP	22634729
glutamate secretion	IEA ISO
negative regulation of transcription by RNA polymerase II	IMP	23021218

GO Hierarchy

biological process

immune system process [inference]

leukocyte activation [inference]

leukocyte activation involved in inflammatory response [inference]

microglial cell activation

myeloid leukocyte activation [inference]

macrophage activation [inference]

microglial cell activation

metabolic process [inference]

primary metabolic process [inference]

lipid metabolic process

organic substance metabolic process [inference]

lipid metabolic process

adaptive thermogenesis [inference]

diet induced thermogenesis

cellular process [inference]

cell activation [inference]

leukocyte activation [inference]

leukocyte activation involved in inflammatory response [inference]

microglial cell activation

myeloid leukocyte activation [inference]

macrophage activation [inference]

microglial cell activation

glial cell activation [inference]

microglial cell activation

signal transduction [inference]

intracellular signal transduction [inference]

second-messenger-mediated signaling [inference]

calcium-mediated signaling

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to heat

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus

cellular response to tumor necrosis factor

cellular response to organic cyclic compound [inference]

cellular response to ATP

cellular response to organonitrogen compound [inference]

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to oxygen-containing compound [inference]

cellular response to ATP

cellular response to salt [inference]

cellular response to ATP

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to pH [inference]

cellular response to acidic pH

transmembrane transport [inference]

monoatomic ion transmembrane transport

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport

calcium ion transmembrane import into cytosol [inference]

calcium ion import across plasma membrane

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

calcium ion transmembrane transport

calcium ion transmembrane import into cytosol [inference]

calcium ion import across plasma membrane

inorganic cation import across plasma membrane [inference]

calcium ion import across plasma membrane

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

calcium ion import across plasma membrane

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

calcium ion import across plasma membrane

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein homooligomerization [inference]

protein homotetramerization

protein tetramerization [inference]

protein homotetramerization

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein homooligomerization [inference]

protein homotetramerization

protein tetramerization [inference]

protein homotetramerization

export from cell [inference]

secretion by cell [inference]

glutamate secretion

multicellular organismal process [inference]

cell activation [inference]

leukocyte activation [inference]

leukocyte activation involved in inflammatory response [inference]

microglial cell activation

myeloid leukocyte activation [inference]

macrophage activation [inference]

microglial cell activation

glial cell activation [inference]

microglial cell activation

system process [inference]

muscle system process [inference]

muscle contraction [inference]

smooth muscle contraction [inference]

urinary tract smooth muscle contraction [inference]

urinary bladder smooth muscle contraction

smooth muscle contraction involved in micturition

nervous system process [inference]

sensory perception [inference]

sensory perception of chemical stimulus [inference]

sensory perception of taste

sensory perception of pain

sensory perception of temperature stimulus [inference]

thermoception

sensory perception of mechanical stimulus

behavior [inference]

behavioral response to pain

multicellular organismal response to stress [inference]

response to pain

multicellular organismal-level homeostasis [inference]

temperature homeostasis

heat generation [inference]

fever generation

homeostatic process [inference]

multicellular organismal-level homeostasis [inference]

temperature homeostasis

heat generation [inference]

fever generation

biological phase [inference]

hair cycle phase [inference]

catagen

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response [inference]

acute inflammatory response [inference]

acute-phase response [inference]

fever generation

response to heat

cellular response to heat

cellular response to stress [inference]

cellular response to heat

multicellular organismal response to stress [inference]

response to pain

response to external stimulus [inference]

detection of external stimulus [inference]

detection of temperature stimulus [inference]

detection of temperature stimulus involved in sensory perception [inference]

response to abiotic stimulus [inference]

response to temperature stimulus [inference]

response to heat

cellular response to heat

detection of temperature stimulus [inference]

detection of temperature stimulus involved in sensory perception [inference]

cellular response to temperature stimulus

response to pH

response to acidic pH [inference]

cellular response to acidic pH

cellular response to pH [inference]

cellular response to acidic pH

detection of abiotic stimulus [inference]

detection of temperature stimulus [inference]

detection of temperature stimulus involved in sensory perception [inference]

cellular response to abiotic stimulus [inference]

cellular response to pH [inference]

cellular response to acidic pH

response to endogenous stimulus [inference]

response to hormone [inference]

response to peptide hormone

response to growth factor [inference]

cellular response to growth factor stimulus [inference]

cellular response to nerve growth factor stimulus

response to nerve growth factor [inference]

cellular response to nerve growth factor stimulus

cellular response to endogenous stimulus [inference]

cellular response to growth factor stimulus [inference]

cellular response to nerve growth factor stimulus

cellular response to organonitrogen compound [inference]

response to chemical [inference]

response to organic substance [inference]

response to hormone [inference]

response to peptide hormone

response to organonitrogen compound

response to purine-containing compound [inference]

response to ATP [inference]

cellular response to ATP

response to alkaloid [inference]

cellular response to alkaloid

cellular response to organonitrogen compound [inference]

response to capsazepine

response to peptide [inference]

response to peptide hormone

response to organic cyclic compound [inference]

response to purine-containing compound [inference]

response to ATP [inference]

cellular response to ATP

cellular response to organic cyclic compound [inference]

cellular response to ATP

response to capsazepine

response to cytokine [inference]

response to tumor necrosis factor [inference]

cellular response to tumor necrosis factor

cellular response to cytokine stimulus

cellular response to tumor necrosis factor

response to organophosphorus [inference]

response to ATP [inference]

cellular response to ATP

cellular response to organic substance [inference]

cellular response to cytokine stimulus

cellular response to tumor necrosis factor

cellular response to organic cyclic compound [inference]

cellular response to ATP

cellular response to organonitrogen compound [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus

cellular response to tumor necrosis factor

cellular response to organic cyclic compound [inference]

cellular response to ATP

cellular response to organonitrogen compound [inference]

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to oxygen-containing compound [inference]

cellular response to ATP

cellular response to salt [inference]

cellular response to ATP

response to nitrogen compound [inference]

response to organonitrogen compound

response to purine-containing compound [inference]

response to ATP [inference]

cellular response to ATP

response to alkaloid [inference]

cellular response to alkaloid

cellular response to organonitrogen compound [inference]

response to capsazepine

response to peptide [inference]

response to peptide hormone

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

response to oxygen-containing compound [inference]

response to ATP [inference]

cellular response to ATP

response to capsazepine

response to peptide [inference]

response to peptide hormone

cellular response to oxygen-containing compound [inference]

cellular response to ATP

response to salt [inference]

response to ATP [inference]

cellular response to ATP

cellular response to salt [inference]

cellular response to ATP

detection of stimulus [inference]

detection of external stimulus [inference]

detection of temperature stimulus [inference]

detection of temperature stimulus involved in sensory perception [inference]

detection of abiotic stimulus [inference]

detection of temperature stimulus [inference]

detection of temperature stimulus involved in sensory perception [inference]

detection of chemical stimulus [inference]

detection of chemical stimulus involved in sensory perception [inference]

detection of chemical stimulus involved in sensory perception of pain

detection of stimulus involved in sensory perception [inference]

detection of chemical stimulus involved in sensory perception [inference]

detection of chemical stimulus involved in sensory perception of pain

detection of temperature stimulus involved in sensory perception [inference]

detection of stimulus involved in sensory perception of pain [inference]

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to heat

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus

cellular response to tumor necrosis factor

cellular response to organic cyclic compound [inference]

cellular response to ATP

cellular response to organonitrogen compound [inference]

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to oxygen-containing compound [inference]

cellular response to ATP

cellular response to salt [inference]

cellular response to ATP

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to pH [inference]

cellular response to acidic pH

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport

metal ion transport [inference]

calcium ion transport

calcium ion transmembrane transport

calcium ion transmembrane import into cytosol [inference]

calcium ion import across plasma membrane

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport

calcium ion transmembrane import into cytosol [inference]

calcium ion import across plasma membrane

monoatomic ion transmembrane transport

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport

calcium ion transmembrane import into cytosol [inference]

calcium ion import across plasma membrane

secretion [inference]

peptide secretion

secretion by cell [inference]

glutamate secretion

transmembrane transport [inference]

monoatomic ion transmembrane transport

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport

calcium ion transmembrane import into cytosol [inference]

calcium ion import across plasma membrane

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

calcium ion transmembrane transport

calcium ion transmembrane import into cytosol [inference]

calcium ion import across plasma membrane

inorganic cation import across plasma membrane [inference]

calcium ion import across plasma membrane

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

calcium ion import across plasma membrane

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

calcium ion import across plasma membrane

organic substance transport [inference]

calcium ion transport

calcium ion transmembrane transport

calcium ion transmembrane import into cytosol [inference]

calcium ion import across plasma membrane

organic anion transport [inference]

carboxylic acid transport [inference]

dicarboxylic acid transport [inference]

glutamate secretion

amino acid transport [inference]

acidic amino acid transport [inference]

glutamate secretion

peptide transport [inference]

peptide secretion

organic acid transport [inference]

carboxylic acid transport [inference]

dicarboxylic acid transport [inference]

glutamate secretion

amino acid transport [inference]

acidic amino acid transport [inference]

glutamate secretion

nitrogen compound transport [inference]

amino acid transport [inference]

acidic amino acid transport [inference]

glutamate secretion

amide transport [inference]

glutamate secretion

peptide transport [inference]

peptide secretion

import into cell [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

calcium ion import across plasma membrane

export from cell [inference]

secretion by cell [inference]

glutamate secretion

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of nitric oxide biosynthetic process

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of cellular biosynthetic process [inference]

positive regulation of nitric oxide biosynthetic process

regulation of nitric oxide biosynthetic process [inference]

positive regulation of nitric oxide biosynthetic process

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of nitric oxide biosynthetic process

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of nitric oxide biosynthetic process

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nitric oxide metabolic process [inference]

positive regulation of nitric oxide biosynthetic process

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of nitric oxide biosynthetic process

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of cellular biosynthetic process [inference]

positive regulation of nitric oxide biosynthetic process

regulation of nitric oxide biosynthetic process [inference]

positive regulation of nitric oxide biosynthetic process

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nitric oxide metabolic process [inference]

positive regulation of nitric oxide biosynthetic process

regulation of nitric oxide metabolic process [inference]

regulation of nitric oxide biosynthetic process [inference]

positive regulation of nitric oxide biosynthetic process

positive regulation of nitric oxide metabolic process [inference]

positive regulation of nitric oxide biosynthetic process

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of nitric oxide biosynthetic process

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of nitric oxide biosynthetic process

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nitric oxide metabolic process [inference]

positive regulation of nitric oxide biosynthetic process

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of nitric oxide biosynthetic process

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of establishment of blood-brain barrier

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of establishment of blood-brain barrier

negative regulation of multicellular organismal process [inference]

negative regulation of blood circulation [inference]

negative regulation of heart contraction [inference]

negative regulation of heart rate

regulation of developmental process [inference]

regulation of cell differentiation [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of establishment of blood-brain barrier

regulation of cell development [inference]

negative regulation of cell development [inference]

negative regulation of establishment of blood-brain barrier

regulation of establishment of blood-brain barrier [inference]

negative regulation of establishment of blood-brain barrier

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of establishment of blood-brain barrier

regulation of cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

second-messenger-mediated signaling [inference]

calcium-mediated signaling

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of nitric oxide biosynthetic process

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of cellular biosynthetic process [inference]

positive regulation of nitric oxide biosynthetic process

regulation of nitric oxide biosynthetic process [inference]

positive regulation of nitric oxide biosynthetic process

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

positive regulation of apoptotic process

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process

regulation of cell differentiation [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of establishment of blood-brain barrier

regulation of cell development [inference]

negative regulation of cell development [inference]

negative regulation of establishment of blood-brain barrier

regulation of establishment of blood-brain barrier [inference]

negative regulation of establishment of blood-brain barrier

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of nitric oxide biosynthetic process

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of establishment of blood-brain barrier

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of blood circulation [inference]

regulation of heart contraction [inference]

regulation of heart rate [inference]

negative regulation of heart rate

negative regulation of heart contraction [inference]

negative regulation of heart rate

negative regulation of blood circulation [inference]

negative regulation of heart contraction [inference]

negative regulation of heart rate

negative regulation of multicellular organismal process [inference]

negative regulation of blood circulation [inference]

negative regulation of heart contraction [inference]

negative regulation of heart rate

regulation of biological quality [inference]

regulation of heart rate [inference]

negative regulation of heart rate

positive regulation of cytosolic calcium ion concentration

regulation of blood pressure [inference]

negative regulation of blood pressure [inference]

negative regulation of systemic arterial blood pressure

regulation of membrane potential [inference]

negative regulation of membrane potential [inference]

negative regulation of mitochondrial membrane potential

regulation of mitochondrial membrane potential [inference]

negative regulation of mitochondrial membrane potential

regulation of postsynaptic membrane potential [inference]

excitatory postsynaptic potential

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GO Term	Evidence Code	PMID
external side of plasma membrane	IEA ISO
membrane	ISA ISO ISS	15883036
postsynaptic membrane	IDA IMP ISO	25775089
neuronal cell body	IEA ISO
plasma membrane	IBA IDA ISO ISS	18455988

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

plasma membrane region [inference]

cell projection membrane [inference]

neuron projection membrane [inference]

dendritic spine membrane

synaptic membrane [inference]

cell junction [inference]

synapse [inference]

GABA-ergic synapse

leading edge membrane [inference]

neuron projection membrane [inference]

dendritic spine membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection

dendrite

cell body [inference]

neuronal cell body

side of membrane [inference]

external side of plasma membrane

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GO Term	Evidence Code	PMID
protein binding	IPI	18455988 25640077
monoatomic cation transmembrane transporter activity	ISO
phosphoprotein binding	IEA ISO
ligand-gated monoatomic ion channel activity	ISO
calmodulin binding	ISO ISS

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic ion channel activity [inference]

monoatomic cation channel activity

calcium channel activity

ligand-gated calcium channel activity [inference]

calcium-release channel activity

ligand-gated monoatomic cation channel activity [inference]

ligand-gated calcium channel activity [inference]

calcium-release channel activity

ligand-gated monoatomic ion channel activity

intracellular ligand-gated monoatomic ion channel activity [inference]

calcium-release channel activity

extracellular ligand-gated monoatomic ion channel activity

excitatory extracellular ligand-gated monoatomic ion channel activity

ligand-gated monoatomic cation channel activity [inference]

ligand-gated calcium channel activity [inference]

calcium-release channel activity

temperature-gated ion channel activity

monoatomic cation transmembrane transporter activity

monoatomic cation channel activity

calcium channel activity

ligand-gated calcium channel activity [inference]

calcium-release channel activity

ligand-gated monoatomic cation channel activity [inference]

ligand-gated calcium channel activity [inference]

calcium-release channel activity

metal ion transmembrane transporter activity [inference]

calcium ion transmembrane transporter activity [inference]

calcium channel activity

ligand-gated calcium channel activity [inference]

calcium-release channel activity

inorganic molecular entity transmembrane transporter activity [inference]

inorganic cation transmembrane transporter activity [inference]

metal ion transmembrane transporter activity [inference]

calcium ion transmembrane transporter activity [inference]

calcium channel activity

ligand-gated calcium channel activity [inference]

calcium-release channel activity

passive transmembrane transporter activity [inference]

channel activity [inference]

monoatomic ion channel activity [inference]

monoatomic cation channel activity

calcium channel activity

ligand-gated calcium channel activity [inference]

calcium-release channel activity

ligand-gated monoatomic cation channel activity [inference]

ligand-gated calcium channel activity [inference]

calcium-release channel activity

ligand-gated monoatomic ion channel activity

intracellular ligand-gated monoatomic ion channel activity [inference]

calcium-release channel activity

extracellular ligand-gated monoatomic ion channel activity

excitatory extracellular ligand-gated monoatomic ion channel activity

ligand-gated monoatomic cation channel activity [inference]

ligand-gated calcium channel activity [inference]

calcium-release channel activity

temperature-gated ion channel activity

gated channel activity [inference]

ligand-gated channel activity [inference]

ligand-gated monoatomic ion channel activity

intracellular ligand-gated monoatomic ion channel activity [inference]

calcium-release channel activity

extracellular ligand-gated monoatomic ion channel activity

excitatory extracellular ligand-gated monoatomic ion channel activity

ligand-gated monoatomic cation channel activity [inference]

ligand-gated calcium channel activity [inference]

calcium-release channel activity

temperature-gated ion channel activity

salt transmembrane transporter activity [inference]

calcium ion transmembrane transporter activity [inference]

calcium channel activity

ligand-gated calcium channel activity [inference]

calcium-release channel activity

binding [inference]

protein binding

lipid binding [inference]

phospholipid binding [inference]

phosphatidylinositol binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

cation binding [inference]

metal ion binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity

molecular function regulator activity [inference]

transporter regulator activity [inference]

channel regulator activity [inference]

ion channel regulator activity [inference]

chloride channel regulator activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

transient receptor potential cation channel subfamily V member 1

Functional Category

G: Carbohydrate transport and metabolism
K: Transcription
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 7** entries
Gene Ontology
ATP binding
calcium channel activity
calmodulin binding
metal ion binding
monoatomic ion channel activity
monoatomic ion transport
nucleotide binding

Displaying **all 5** entries
InterPro
Ankyrin repeat-containing domain superfamily
Ankyrin repeat
Ion transport domain
Transient receptor potential cation channel subfamily V member 1-4
Transient receptor potential cation channel subfamily V

Disease

Disease Ontology

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:2548	reflex epilepsy	Alliance of Genome Resources
DOID:5844	myocardial infarction	Alliance of Genome Resources
DOID:6364	migraine	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 98 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	7442		HGNC:12716	HUMAN30853
Drosophila melanogaster	39571		FB:FBgn0036414
Rattus norvegicus	83810	10116_1:0034c5	RGD:628841	RATNO00242
Caenorhabditis elegans	177506		WB:WBGene00003841
Canis lupus familiaris	445457			CANLF19187
Danio rerio	561195		ZFIN:ZDB-GENE-030912-8
Macaca mulatta	721455			MACMU15712
Pan troglodytes	750493			PANTR13252
Saccharomyces cerevisiae S288C	854255		SGD:S000005613
Oryctolagus cuniculus	100008926			RABIT07302

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements