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RAN binding protein 2

Summary

Gene Symbol

Ranbp2

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

19386

PubChem

19386

Alliance of Genome Resources

MGI:894323

Annotation

Keyword

Acetylation
Disulfide bond
Isopeptide bond
Membrane
Methylation
Nuclear pore complex
Phosphoprotein
RNA-binding
Reference proteome
Repeat
TPR repeat
Transferase
Ubl conjugation
Ubl conjugation pathway
Zinc-finger

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9ERU9	Ran-binding protein 2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
protein peptidyl-prolyl isomerization
response to amphetamine	IEA
regulation of gluconeogenesis	IMP	17069463
protein folding	IEA
NLS-bearing protein import into nucleus	IBA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

peptidyl-amino acid modification [inference]

peptidyl-lysine modification [inference]

protein sumoylation

peptidyl-proline modification [inference]

protein peptidyl-prolyl isomerization

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein sumoylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

peptidyl-amino acid modification [inference]

peptidyl-lysine modification [inference]

protein sumoylation

peptidyl-proline modification [inference]

protein peptidyl-prolyl isomerization

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein sumoylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

peptidyl-amino acid modification [inference]

peptidyl-lysine modification [inference]

protein sumoylation

peptidyl-proline modification [inference]

protein peptidyl-prolyl isomerization

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein sumoylation

macromolecule modification [inference]

protein modification process [inference]

peptidyl-amino acid modification [inference]

peptidyl-lysine modification [inference]

protein sumoylation

peptidyl-proline modification [inference]

protein peptidyl-prolyl isomerization

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein sumoylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

peptidyl-amino acid modification [inference]

peptidyl-lysine modification [inference]

protein sumoylation

peptidyl-proline modification [inference]

protein peptidyl-prolyl isomerization

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein sumoylation

cellular process [inference]

protein folding

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport

nuclear export

import into nucleus [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to nucleus [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

microtubule organizing center localization [inference]

centrosome localization

response to stimulus [inference]

response to chemical [inference]

response to organic substance [inference]

response to organonitrogen compound [inference]

response to amine [inference]

response to amphetamine

response to nitrogen compound [inference]

response to organonitrogen compound [inference]

response to amine [inference]

response to amphetamine

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to nucleus [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

establishment of localization [inference]

transport [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport

nuclear export

import into nucleus [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

organic substance transport [inference]

protein transport [inference]

intracellular protein transport [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

nucleobase-containing compound transport [inference]

nucleic acid transport [inference]

RNA transport [inference]

mRNA transport

nitrogen compound transport [inference]

protein transport [inference]

intracellular protein transport [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

nucleobase-containing compound transport [inference]

nucleic acid transport [inference]

RNA transport [inference]

mRNA transport

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

establishment of RNA localization [inference]

RNA transport [inference]

mRNA transport

establishment of localization in cell [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport

nuclear export

import into nucleus [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport

nuclear export

import into nucleus [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to nucleus [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus [inference]

NLS-bearing protein import into nucleus

microtubule organizing center localization [inference]

centrosome localization

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of carbohydrate biosynthetic process [inference]

regulation of gluconeogenesis

regulation of small molecule metabolic process [inference]

regulation of glucose metabolic process [inference]

regulation of gluconeogenesis

regulation of primary metabolic process [inference]

regulation of carbohydrate metabolic process [inference]

regulation of glucose metabolic process [inference]

regulation of gluconeogenesis

regulation of carbohydrate biosynthetic process [inference]

regulation of gluconeogenesis

Displaying entries **1 - 5** of 25 in total

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GO Term	Evidence Code	PMID
nuclear envelope	ISS
nuclear envelope	ISO
nuclear envelope	TAS
annulate lamellae	ISS
annulate lamellae	ISO

GO Hierarchy

cellular component

protein-containing complex [inference]

nuclear protein-containing complex [inference]

catalytic complex [inference]

transferase complex [inference]

SUMO ligase complex

cellular anatomical entity [inference]

intracellular anatomical structure [inference]

inclusion body [inference]

nuclear inclusion body

membrane [inference]

annulate lamellae

organelle membrane [inference]

nuclear membrane

envelope [inference]

organelle envelope [inference]

nuclear envelope

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle

intracellular organelle [inference]

intracellular membrane-bounded organelle

perinuclear region of cytoplasm [inference]

cytoplasmic periphery of the nuclear pore complex

Displaying entries **1 - 5** of 14 in total

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GO Term	Evidence Code	PMID
RNA binding	IEA
peptidyl-prolyl cis-trans isomerase activity	IEA
GTPase activator activity	IBA
protein binding	IPI	16332688 17069463 35771867
zinc ion binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

acyltransferase activity [inference]

aminoacyltransferase activity [inference]

ubiquitin-like protein transferase activity [inference]

SUMO transferase activity

SUMO ligase activity

ubiquitin-like protein ligase activity [inference]

SUMO ligase activity

isomerase activity [inference]

cis-trans isomerase activity [inference]

peptidyl-prolyl cis-trans isomerase activity

catalytic activity, acting on a protein [inference]

peptidyl-prolyl cis-trans isomerase activity

ubiquitin-like protein transferase activity [inference]

SUMO transferase activity

SUMO ligase activity

ubiquitin-like protein ligase activity [inference]

SUMO ligase activity

binding [inference]

protein binding

enzyme binding [inference]

GTPase binding [inference]

small GTPase binding

ion binding [inference]

cation binding [inference]

metal ion binding

transition metal ion binding [inference]

zinc ion binding

protein-containing complex binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

RNA binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme activator activity [inference]

kinase regulator activity [inference]

kinase activator activity

nucleoside-triphosphatase regulator activity [inference]

GTPase regulator activity [inference]

GTPase activator activity

molecular function activator activity [inference]

enzyme activator activity [inference]

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

RanBP2

Functional Category

E: Amino acid transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
NLS-bearing protein import into nucleus
positive regulation of mitotic centrosome separation

Displaying **all 4** entries
InterPro
PH-like domain superfamily
Ran binding domain
Ran binding protein RanBP1-like
Ran-specific GTPase-activating protein 1, Ran-binding domain

Ortholog

Displaying entries **1 - 10** of **105** in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	5903	Xenbase:XB-GENE-492821	HUMAN64240
Xenopus tropicalis	19386	Xenbase:XB-GENE-492821
Homo sapiens	84220	ZFIN:ZDB-GENE-081104-93	HUMAN64302
Homo sapiens	285190	Xenbase:XB-GENE-492821	HUMAN64208
Rattus norvegicus	294429		RATNO22079
Homo sapiens	400966	ZFIN:ZDB-GENE-081104-93	HUMAN63712
Canis lupus familiaris	474539		CANLF01713
Homo sapiens	653489	Xenbase:XB-GENE-492821	HUMAN64199
Macaca mulatta	694823		MACMU07758
Homo sapiens	727851	Xenbase:XB-GENE-492821	HUMAN64375