GlyCosmos Portal

Annotation

Keyword

Calcium
Cell membrane
Developmental protein
Disulfide bond
EGF-like domain
G-protein coupled receptor
Glycoprotein
Hydroxylation
Laminin EGF-like domain
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9HCU4	Cadherin family member 10 Epidermal growth factor-like protein 2 Flamingo homolog 3 Multiple epidermal growth factor-like domains protein 3

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 16 in total

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GO Term	Evidence Code	PMID
cell-cell adhesion	IBA
neural plate anterior/posterior regionalization	ISS
motor neuron migration	IEA
regulation of protein localization	IEA
cerebrospinal fluid secretion	IEA

GO Hierarchy

biological process

cellular process [inference]

microtubule-based process [inference]

microtubule-based movement [inference]

cilium movement

cell adhesion [inference]

cell-cell adhesion

cell-cell adhesion via plasma-membrane adhesion molecules [inference]

homophilic cell adhesion via plasma membrane adhesion molecules

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Wnt signaling pathway

non-canonical Wnt signaling pathway [inference]

Wnt signaling pathway, planar cell polarity pathway

G protein-coupled receptor signaling pathway

cell motility [inference]

cell migration [inference]

neuron migration [inference]

motor neuron migration

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cilium organization [inference]

cilium assembly

organelle assembly [inference]

cilium assembly

cellular component assembly [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

cilium assembly

organelle assembly [inference]

cilium assembly

cell projection organization [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

cilium assembly

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

neuron projection morphogenesis [inference]

dendrite morphogenesis

plasma membrane bounded cell projection organization [inference]

cilium organization [inference]

cilium assembly

plasma membrane bounded cell projection assembly [inference]

cilium assembly

multicellular organismal process [inference]

pattern specification process [inference]

regionalization [inference]

anterior/posterior pattern specification [inference]

neural plate anterior/posterior regionalization

neural plate regionalization [inference]

neural plate anterior/posterior regionalization

neural plate pattern specification [inference]

neural plate regionalization [inference]

neural plate anterior/posterior regionalization

secretion by tissue [inference]

cerebrospinal fluid secretion

developmental process [inference]

anatomical structure morphogenesis [inference]

cellular anatomical entity morphogenesis [inference]

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

neuron projection morphogenesis [inference]

dendrite morphogenesis

anatomical structure development [inference]

system development [inference]

ventricular system development

localization [inference]

establishment of localization [inference]

transport [inference]

secretion [inference]

body fluid secretion [inference]

cerebrospinal fluid secretion

secretion by tissue [inference]

cerebrospinal fluid secretion

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of localization [inference]

regulation of cellular localization [inference]

regulation of protein localization

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Wnt signaling pathway

non-canonical Wnt signaling pathway [inference]

Wnt signaling pathway, planar cell polarity pathway

G protein-coupled receptor signaling pathway

regulation of cell adhesion [inference]

regulation of cell-cell adhesion

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of cellular localization [inference]

regulation of protein localization

regulation of biological quality [inference]

regulation of body fluid levels [inference]

body fluid secretion [inference]

cerebrospinal fluid secretion

Displaying **all 3** entries
GO Term	Evidence Code	PMID
membrane	NAS	10907856
plasma membrane	ISS
cytoplasm	ISS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

membrane

plasma membrane

Displaying **all 2** entries
GO Term	Evidence Code	PMID
calcium ion binding	IEA
G protein-coupled receptor activity	NAS	10907856

GO Hierarchy

molecular function

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

cadherin EGF LAG seven-pass G-type receptor 3

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
M: Cell wall/membrane/envelope biogenesis

Displaying **all 2** entries
Gene Ontology
calcium ion binding
cell surface receptor signaling pathway

Displaying 1 entry
InterPro
GPCR, family 2-like, 7TM

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:10908	hydrocephalus	Alliance of Genome Resources

Ortholog

Displaying entries **61 - 68** of 68 in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Salmo trutta	115207788		SALTR35792
Sparus aurata	115582997		SPAAU39145
Chelonoidis abingdonii	116836171		CHEAB16759
Rhinolophus ferrumequinum	117014488		RHIFE26132
Balaenoptera musculus	118900652		BALMU23517
Panthera leo	122228274		PANLE09919
Ursus americanus	123795118		URSAM16713
Pongo pygmaeus	129040287	9600_0:000010

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements