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epidermal growth factor receptor
Summary
- Gene Symbol
-
- EGFR
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Alternative splicing
- Cell membrane
- Developmental protein
- Direct protein sequencing
- Disease variant
- Disulfide bond
- Endoplasmic reticulum
- Endosome
- Glycoprotein
- Golgi apparatus
- Host cell receptor for virus entry
- Host-virus interaction
- Hydroxylation
- Isopeptide bond
- Methylation
- Nucleus
- Palmitate
- Phosphoprotein
- Proteomics identification
- Proto-oncogene
- Receptor
- Reference proteome
- Repeat
- Secreted
- Signal
- Transmembrane helix
- Tyrosine-protein kinase
- Ubl conjugation
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| positive regulation of fibroblast proliferation | ||
| positive regulation of cell population proliferation | ||
| cell-cell adhesion | ||
| positive regulation of vasoconstriction | ||
| cellular response to mechanical stimulus |
GO Hierarchy
- positive regulation of cell growth
- positive regulation of cell growth
biological process
metabolic process [inference]
cellular process [inference]
response to stimulus [inference]
response to endogenous stimulus [inference]
response to chemical [inference]
cellular response to stimulus [inference]
localization [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of metabolic process [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of nitrogen compound metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of phosphorus metabolic process [inference]
positive regulation of phosphorus metabolic process [inference]
regulation of phosphate metabolic process [inference]
regulation of phosphorylation [inference]
regulation of protein phosphorylation [inference]
positive regulation of phosphorylation
regulation of kinase activity [inference]
positive regulation of phosphate metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of nitrogen compound metabolic process [inference]
regulation of protein metabolic process [inference]
regulation of protein modification process [inference]
regulation of protein phosphorylation [inference]
regulation of macromolecule metabolic process [inference]
regulation of macromolecule biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
regulation of protein metabolic process [inference]
regulation of protein modification process [inference]
regulation of protein phosphorylation [inference]
regulation of primary metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
regulation of protein metabolic process [inference]
regulation of protein modification process [inference]
regulation of protein phosphorylation [inference]
regulation of signaling
regulation of localization [inference]
positive regulation of biological process [inference]
positive regulation of metabolic process [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of nitrogen compound metabolic process [inference]
positive regulation of signaling [inference]
positive regulation of cellular process [inference]
positive regulation of cell communication [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cell cycle [inference]
positive regulation of response to stimulus [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of signal transduction [inference]
positive regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of cell communication
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of phosphorus metabolic process [inference]
positive regulation of phosphorus metabolic process [inference]
regulation of phosphate metabolic process [inference]
regulation of phosphorylation [inference]
regulation of protein phosphorylation [inference]
positive regulation of phosphorylation
regulation of kinase activity [inference]
positive regulation of phosphate metabolic process [inference]
regulation of cell population proliferation
regulation of cell differentiation [inference]
positive regulation of cellular process [inference]
positive regulation of cell communication [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cell cycle [inference]
regulation of cell cycle [inference]
regulation of cellular localization [inference]
regulation of multicellular organismal process [inference]
regulation of molecular function [inference]
positive regulation of molecular function [inference]
regulation of catalytic activity [inference]
positive regulation of catalytic activity [inference]
regulation of transferase activity [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| cell junction | ||
| nuclear membrane | ||
| membrane | ||
| multivesicular body, internal vesicle lumen | ||
| focal adhesion |
GO Hierarchy
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- protein kinase
- Functional Category
-
- K: Transcription
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050589 | inflammatory bowel disease | |
| DOID:0050700 | cardiomyopathy | |
| DOID:0050866 | oral squamous cell carcinoma | |
| DOID:0080599 | Coronavirus infectious disease | |
| DOID:0080855 | Parkinsonism | |
| DOID:10155 | intestinal cancer | |
| DOID:10283 | prostate cancer | |
| DOID:10763 | hypertension | |
| DOID:11054 | urinary bladder cancer | |
| DOID:11166 | Human papillomavirus infectious disease |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 13649 | MGI:95294 | MOUSE07215 | ||
| 24329 | RGD:2543 | RATNO08169 | ||
| 37455 | FB:FBgn0003731 | |||
| 174462 | WB:WBGene00002299 | |||
| 378478 | ZFIN:ZDB-GENE-030918-1 | DANRE29317 | ||
| 397070 | PIGXX36851 | |||
| 404306 | CANLF05488 | |||
| 463415 | 9598_0:00214c | PANTR40281 | ||
| 613027 | MACMU32409 | |||
| 724072 | Xenbase:XB-GENE-6067157 |
