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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
aryl hydrocarbon receptor
Summary
- Gene Symbol
-
- AHR
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- ADP-ribosylation
- Acetylation
- Activator
- Biological rhythms
- Cell cycle
- Cytoplasm
- DNA-binding
- Nucleus
- Receptor
- Reference proteome
- Repeat
- Repressor
- Retinitis pigmentosa
- Transcription regulation
- Proteins
| UniProt | Protein Name |
|---|---|
| P35869 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| response to toxic substance | ||
| regulation of B cell proliferation | ||
| cAMP-mediated signaling | ||
| cellular response to forskolin | ||
| response to xenobiotic stimulus |
GO Hierarchy
biological process
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of primary metabolic process [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| nuclear aryl hydrocarbon receptor complex | ||
| cytosolic aryl hydrocarbon receptor complex | ||
| protein-containing complex | ||
| nucleoplasm | ||
| transcription regulator complex |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| E-box binding | ||
| protein binding | ||
| DNA binding | ||
| Hsp90 protein binding | ||
| RNA polymerase II-specific DNA-binding transcription factor binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- aryl hydrocarbon receptor
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| intracellular receptor signaling pathway |
| protein dimerization activity |
| rhythmic process |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050741 | alcohol dependence | |
| DOID:0081292 | traumatic brain injury | |
| DOID:0112142 | retinitis pigmentosa 85 | |
| DOID:10763 | hypertension | |
| DOID:11984 | hypertrophic cardiomyopathy | |
| DOID:12351 | alcoholic hepatitis | |
| DOID:1793 | pancreatic cancer | |
| DOID:224 | transient cerebral ischemia | |
| DOID:6432 | pulmonary hypertension | |
| DOID:9649 | congenital nystagmus |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 11622 | MGI:105043 | MOUSE08797 | ||
| 25690 | RGD:2074 | RATNO35701 | ||
| 41988 | FB:FBgn0003513 | |||
| 172788 | WB:WBGene00000096 | |||
| 246224 | ZFIN:ZDB-GENE-020531-2 | |||
| 280714 | BOVIN27724 | |||
| 396654 | PIGXX36191 | |||
| 398659 | Xenbase:XB-GENE-983111 | |||
| 443467 | SHEEP15349 | |||
| 463278 | 9598_0:0021d3 | PANTR39765 |
