GlyCosmos Portal

Displaying **all 5** entries
GO Term	Evidence Code	PMID
minus-end-directed microtubule motor activity	IBA
dynein intermediate chain binding	IBA
ATP hydrolysis activity	IEA
dynein light intermediate chain binding	IBA
ATP binding	IEA

GO Hierarchy

molecular function

cytoskeletal motor activity [inference]

microtubule motor activity [inference]

minus-end-directed microtubule motor activity

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

ATP hydrolysis activity

binding [inference]

protein binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ATP-dependent activity [inference]

microtubule motor activity [inference]

minus-end-directed microtubule motor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Dyneins heavy chain

Functional Category

J: Translation, ribosomal structure and biogenesis
L: Replication, recombination and repair
V: Defense mechanisms

Displaying **all 6** entries
Gene Ontology
ATP binding
cilium movement involved in cell motility
dynein intermediate chain binding
dynein light intermediate chain binding
microtubule-based movement
minus-end-directed microtubule motor activity

Displaying **all 3** entries
InterPro
Dynein heavy chain, tail
Dynein heavy chain
P-loop containing nucleoside triphosphate hydrolase

Disease

Disease Ontology

Displaying **all 4** entries
DO ID	Disease Name	Source
DOID:0060250	idiopathic scoliosis	Alliance of Genome Resources
DOID:0111910	spermatogenic failure	Alliance of Genome Resources
DOID:0112336	spermatogenic failure 56	Alliance of Genome Resources
DOID:9970	obesity	Alliance of Genome Resources

Ortholog

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	43379		FB:FBgn0013813
Mus musculus	56087		MGI:1860299	MOUSE44679
Rattus norvegicus	116455			RATNO05007
Rattus norvegicus	117252		RGD:619988	RATNO05007
Pan troglodytes	452355	9598_0:003819		PANTR07218
Danio rerio	569992		ZFIN:ZDB-GENE-060531-163	DANRE35397
Rattus norvegicus	689779			RATNO05007
Macaca mulatta	710343			MACMU04045
Monodelphis domestica	100024148			MONDO18545
Equus caballus	100061177			HORSE41081

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Annotation

OrthoDB (Group)

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Acknowledgements