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dynein axonemal heavy chain 12

Summary

Gene Symbol

DNAH12

Organism

Homo sapiens (human)

External Links

NCBI Gene

201625

PubChem

201625

Alliance of Genome Resources

HGNC:2943

Annotation

Keyword

ATP-binding
Alternative splicing
Cilium
Coiled coil
Cytoskeleton
Dynein
Microtubule
Motor protein
Proteomics identification
Reference proteome
Repeat
Ubl conjugation pathway

Proteins

Displaying 1 entry
UniProt	Protein Name
Q6ZR08	Axonemal beta dynein heavy chain 12 Axonemal dynein heavy chain 12-like protein Axonemal dynein heavy chain 7-like protein Ciliary dynein heavy chain 12 Dynein axonemal heavy chain 7-like Dynein heavy chain domain-containing protein 2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
microtubule-based movement	IEA

GO Hierarchy

biological process

cellular process [inference]

microtubule-based process [inference]

microtubule-based movement

Displaying **all 2** entries
GO Term	Evidence Code	PMID
microtubule	IEA
axonemal dynein complex	IBA

GO Hierarchy

cellular component

protein-containing complex [inference]

microtubule associated complex [inference]

dynein complex [inference]

axonemal dynein complex

catalytic complex [inference]

dynein complex [inference]

axonemal dynein complex

cellular anatomical entity [inference]

supramolecular complex [inference]

supramolecular polymer [inference]

supramolecular fiber [inference]

polymeric cytoskeletal fiber [inference]

microtubule

Displaying **all 5** entries
GO Term	Evidence Code	PMID
minus-end-directed microtubule motor activity	IEA
dynein intermediate chain binding	IEA
ATP hydrolysis activity	IEA
dynein light intermediate chain binding	IEA
ATP binding	IEA

GO Hierarchy

molecular function

cytoskeletal motor activity [inference]

microtubule motor activity [inference]

minus-end-directed microtubule motor activity

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

ATP hydrolysis activity

binding [inference]

protein binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ATP-dependent activity [inference]

microtubule motor activity [inference]

minus-end-directed microtubule motor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

heavy chain of dynein

Functional Category

J: Translation, ribosomal structure and biogenesis
L: Replication, recombination and repair
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
ATP binding
dynein intermediate chain binding
dynein light intermediate chain binding
microtubule-based movement
minus-end-directed microtubule motor activity

Displaying entries **11 - 15** of 15 in total

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InterPro
Dynein heavy chain, domain 2, N-terminal
Dynein heavy chain, hydrolytic ATP-binding dynein motor region
Dynein heavy chain, linker
Dynein heavy chain
P-loop containing nucleoside triphosphate hydrolase

Ortholog

Displaying entries **11 - 20** of 63 in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Taeniopygia guttata	100218248		TAEGU03701
Oryctolagus cuniculus	100353849		RABIT12946
Pongo abelii	100440290	9601_0:0011ab	PONAB25596
Nomascus leucogenys	100600100		NOMLE30211
Bos taurus	100847355		BOVIN17622
Pan paniscus	100990280	9597_0:0010c3	PANPA28118
Papio anubis	101023096		PAPAN24825
Saimiri boliviensis boliviensis	101033827		SAIBB26925
Felis catus	101080950		FELCA05849
Ovis aries	101108960		SHEEP08343

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Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements