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endothelial PAS domain protein 1

Summary

Gene Symbol

EPAS1

Organism

Homo sapiens (human)

External Links

NCBI Gene

2034

PubChem

2034

Alliance of Genome Resources

HGNC:3374

Annotation

Keyword

3D-structure
Activator
Angiogenesis
Congenital erythrocytosis
DNA-binding
Developmental protein
Differentiation
Disease variant
Host-virus interaction
Hydroxylation
Nucleus
Phosphoprotein
Reference proteome
Repeat
Transcription regulation
Ubl conjugation

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q99814	Basic-helix-loop-helix-PAS protein MOP2 Class E basic helix-loop-helix protein 73 HIF-1-alpha-like factor Hypoxia-inducible factor 2-alpha Member of PAS protein 2 PAS domain-containing protein 2
B3KW07

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 23 in total

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GO Term	Evidence Code	PMID
angiogenesis	IEA
response to hypoxia	IDA	11782478
embryonic placenta development	IEA
blood vessel remodeling	IEA
regulation of heart rate	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II [inference]

mRNA transcription by RNA polymerase II

mRNA transcription [inference]

mRNA transcription by RNA polymerase II

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

mRNA metabolic process [inference]

mRNA transcription [inference]

mRNA transcription by RNA polymerase II

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II [inference]

mRNA transcription by RNA polymerase II

mRNA transcription [inference]

mRNA transcription by RNA polymerase II

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II [inference]

mRNA transcription by RNA polymerase II

mRNA transcription [inference]

mRNA transcription by RNA polymerase II

organonitrogen compound metabolic process [inference]

amine metabolic process [inference]

biogenic amine metabolic process [inference]

catecholamine metabolic process [inference]

norepinephrine metabolic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II [inference]

mRNA transcription by RNA polymerase II

mRNA transcription [inference]

mRNA transcription by RNA polymerase II

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II [inference]

mRNA transcription by RNA polymerase II

mRNA transcription [inference]

mRNA transcription by RNA polymerase II

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II [inference]

mRNA transcription by RNA polymerase II

mRNA transcription [inference]

mRNA transcription by RNA polymerase II

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II [inference]

mRNA transcription by RNA polymerase II

mRNA transcription [inference]

mRNA transcription by RNA polymerase II

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II [inference]

mRNA transcription by RNA polymerase II

mRNA transcription [inference]

mRNA transcription by RNA polymerase II

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II [inference]

mRNA transcription by RNA polymerase II

mRNA transcription [inference]

mRNA transcription by RNA polymerase II

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II [inference]

mRNA transcription by RNA polymerase II

mRNA transcription [inference]

mRNA transcription by RNA polymerase II

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

mRNA metabolic process [inference]

mRNA transcription [inference]

mRNA transcription by RNA polymerase II

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II [inference]

mRNA transcription by RNA polymerase II

mRNA transcription [inference]

mRNA transcription by RNA polymerase II

phenol-containing compound metabolic process [inference]

catechol-containing compound metabolic process [inference]

catecholamine metabolic process [inference]

norepinephrine metabolic process

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II [inference]

mRNA transcription by RNA polymerase II

mRNA transcription [inference]

mRNA transcription by RNA polymerase II

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II [inference]

mRNA transcription by RNA polymerase II

mRNA transcription [inference]

mRNA transcription by RNA polymerase II

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

mRNA metabolic process [inference]

mRNA transcription [inference]

mRNA transcription by RNA polymerase II

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II [inference]

mRNA transcription by RNA polymerase II

mRNA transcription [inference]

mRNA transcription by RNA polymerase II

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II [inference]

mRNA transcription by RNA polymerase II

mRNA transcription [inference]

mRNA transcription by RNA polymerase II

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II [inference]

mRNA transcription by RNA polymerase II

mRNA transcription [inference]

mRNA transcription by RNA polymerase II

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II [inference]

mRNA transcription by RNA polymerase II

mRNA transcription [inference]

mRNA transcription by RNA polymerase II

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II [inference]

mRNA transcription by RNA polymerase II

mRNA transcription [inference]

mRNA transcription by RNA polymerase II

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II [inference]

mRNA transcription by RNA polymerase II

mRNA transcription [inference]

mRNA transcription by RNA polymerase II

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II [inference]

mRNA transcription by RNA polymerase II

mRNA transcription [inference]

mRNA transcription by RNA polymerase II

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

mRNA metabolic process [inference]

mRNA transcription [inference]

mRNA transcription by RNA polymerase II

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II [inference]

mRNA transcription by RNA polymerase II

mRNA transcription [inference]

mRNA transcription by RNA polymerase II

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II [inference]

mRNA transcription by RNA polymerase II

mRNA transcription [inference]

mRNA transcription by RNA polymerase II

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II [inference]

mRNA transcription by RNA polymerase II

mRNA transcription [inference]

mRNA transcription by RNA polymerase II

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

mRNA metabolic process [inference]

mRNA transcription [inference]

mRNA transcription by RNA polymerase II

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II [inference]

mRNA transcription by RNA polymerase II

mRNA transcription [inference]

mRNA transcription by RNA polymerase II

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II [inference]

mRNA transcription by RNA polymerase II

mRNA transcription [inference]

mRNA transcription by RNA polymerase II

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

mRNA metabolic process [inference]

mRNA transcription [inference]

mRNA transcription by RNA polymerase II

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II [inference]

mRNA transcription by RNA polymerase II

mRNA transcription [inference]

mRNA transcription by RNA polymerase II

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II [inference]

mRNA transcription by RNA polymerase II

mRNA transcription [inference]

mRNA transcription by RNA polymerase II

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

mRNA metabolic process [inference]

mRNA transcription [inference]

mRNA transcription by RNA polymerase II

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II [inference]

mRNA transcription by RNA polymerase II

mRNA transcription [inference]

mRNA transcription by RNA polymerase II

phenol-containing compound metabolic process [inference]

catechol-containing compound metabolic process [inference]

catecholamine metabolic process [inference]

norepinephrine metabolic process

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II [inference]

mRNA transcription by RNA polymerase II

mRNA transcription [inference]

mRNA transcription by RNA polymerase II

organonitrogen compound metabolic process [inference]

amine metabolic process [inference]

biogenic amine metabolic process [inference]

catecholamine metabolic process [inference]

norepinephrine metabolic process

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II [inference]

mRNA transcription by RNA polymerase II

mRNA transcription [inference]

mRNA transcription by RNA polymerase II

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II [inference]

mRNA transcription by RNA polymerase II

mRNA transcription [inference]

mRNA transcription by RNA polymerase II

organic hydroxy compound metabolic process [inference]

phenol-containing compound metabolic process [inference]

catechol-containing compound metabolic process [inference]

catecholamine metabolic process [inference]

norepinephrine metabolic process

cellular process [inference]

signal transduction

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II [inference]

mRNA transcription by RNA polymerase II

mRNA transcription [inference]

mRNA transcription by RNA polymerase II

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

mRNA metabolic process [inference]

mRNA transcription [inference]

mRNA transcription by RNA polymerase II

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II [inference]

mRNA transcription by RNA polymerase II

mRNA transcription [inference]

mRNA transcription by RNA polymerase II

phenol-containing compound metabolic process [inference]

catechol-containing compound metabolic process [inference]

catecholamine metabolic process [inference]

norepinephrine metabolic process

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II [inference]

mRNA transcription by RNA polymerase II

mRNA transcription [inference]

mRNA transcription by RNA polymerase II

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II [inference]

mRNA transcription by RNA polymerase II

mRNA transcription [inference]

mRNA transcription by RNA polymerase II

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

mRNA metabolic process [inference]

mRNA transcription [inference]

mRNA transcription by RNA polymerase II

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II [inference]

mRNA transcription by RNA polymerase II

mRNA transcription [inference]

mRNA transcription by RNA polymerase II

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II [inference]

mRNA transcription by RNA polymerase II

mRNA transcription [inference]

mRNA transcription by RNA polymerase II

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II [inference]

mRNA transcription by RNA polymerase II

mRNA transcription [inference]

mRNA transcription by RNA polymerase II

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II [inference]

mRNA transcription by RNA polymerase II

mRNA transcription [inference]

mRNA transcription by RNA polymerase II

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II [inference]

mRNA transcription by RNA polymerase II

mRNA transcription [inference]

mRNA transcription by RNA polymerase II

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II [inference]

mRNA transcription by RNA polymerase II

mRNA transcription [inference]

mRNA transcription by RNA polymerase II

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II [inference]

mRNA transcription by RNA polymerase II

mRNA transcription [inference]

mRNA transcription by RNA polymerase II

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

mRNA metabolic process [inference]

mRNA transcription [inference]

mRNA transcription by RNA polymerase II

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II [inference]

mRNA transcription by RNA polymerase II

mRNA transcription [inference]

mRNA transcription by RNA polymerase II

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II [inference]

mRNA transcription by RNA polymerase II

mRNA transcription [inference]

mRNA transcription by RNA polymerase II

cellular developmental process [inference]

cell differentiation [inference]

myeloid cell differentiation [inference]

erythrocyte differentiation

cell fate commitment [inference]

myoblast fate commitment

cell maturation [inference]

epithelial cell maturation

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to hypoxia

cellular response to chemical stimulus [inference]

cellular response to oxygen levels [inference]

cellular response to decreased oxygen levels [inference]

cellular response to hypoxia

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

mitochondrion organization

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

sensory perception [inference]

sensory perception of light stimulus [inference]

visual perception

tissue remodeling [inference]

blood vessel remodeling

multicellular organismal-level homeostasis [inference]

multicellular organismal-level chemical homeostasis [inference]

developmental process [inference]

developmental maturation [inference]

anatomical structure maturation [inference]

cell maturation [inference]

epithelial cell maturation

anatomical structure formation involved in morphogenesis [inference]

angiogenesis

anatomical structure development [inference]

animal organ development [inference]

lung development

embryonic organ development [inference]

embryonic placenta development

cellular developmental process [inference]

cell differentiation [inference]

myeloid cell differentiation [inference]

erythrocyte differentiation

cell fate commitment [inference]

myoblast fate commitment

cell maturation [inference]

epithelial cell maturation

homeostatic process [inference]

multicellular organismal-level homeostasis [inference]

multicellular organismal-level chemical homeostasis [inference]

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

monoatomic cation homeostasis [inference]

multicellular organismal-level iron ion homeostasis

inorganic ion homeostasis [inference]

multicellular organismal-level iron ion homeostasis

multicellular organismal-level chemical homeostasis [inference]

response to stimulus [inference]

response to stress [inference]

response to hypoxia

cellular response to hypoxia

response to oxidative stress

cellular response to stress [inference]

cellular response to hypoxia

response to abiotic stimulus [inference]

response to oxygen levels [inference]

response to decreased oxygen levels [inference]

response to hypoxia

cellular response to hypoxia

cellular response to decreased oxygen levels [inference]

cellular response to hypoxia

cellular response to oxygen levels [inference]

cellular response to decreased oxygen levels [inference]

cellular response to hypoxia

response to chemical [inference]

cellular response to chemical stimulus [inference]

cellular response to oxygen levels [inference]

cellular response to decreased oxygen levels [inference]

cellular response to hypoxia

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to hypoxia

cellular response to chemical stimulus [inference]

cellular response to oxygen levels [inference]

cellular response to decreased oxygen levels [inference]

cellular response to hypoxia

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cold-induced thermogenesis

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of post-translational protein modification [inference]

regulation of protein modification by small protein conjugation or removal [inference]

regulation of protein neddylation

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of post-translational protein modification [inference]

regulation of protein modification by small protein conjugation or removal [inference]

regulation of protein neddylation

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of post-translational protein modification [inference]

regulation of protein modification by small protein conjugation or removal [inference]

regulation of protein neddylation

regulation of cold-induced thermogenesis [inference]

positive regulation of cold-induced thermogenesis

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cold-induced thermogenesis

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of multicellular organismal process [inference]

positive regulation of cold-induced thermogenesis

regulation of cellular process [inference]

signal transduction

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of blood circulation [inference]

regulation of heart contraction [inference]

regulation of heart rate

positive regulation of multicellular organismal process [inference]

positive regulation of cold-induced thermogenesis

regulation of cold-induced thermogenesis [inference]

positive regulation of cold-induced thermogenesis

regulation of biological quality [inference]

regulation of heart rate

Displaying **all 5** entries
GO Term	Evidence Code	PMID
chromatin	ISA
nucleoplasm	TAS
transcription regulator complex	IDA	9000051
cytosol	TAS
nuclear speck	IEA

GO Hierarchy

cellular component

protein-containing complex [inference]

transcription regulator complex

protein-DNA complex [inference]

chromatin

cellular anatomical entity [inference]

nuclear body [inference]

nuclear speck

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GO Term	Evidence Code	PMID
RNA polymerase II transcription regulatory region sequence-specific DNA binding	IBA
RNA polymerase II cis-regulatory region sequence-specific DNA binding	IEA
DNA-binding transcription factor activity, RNA polymerase II-specific	ISA
DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
transcription coactivator binding	IPI	15261140

GO Hierarchy

molecular function

binding [inference]

protein binding

transcription factor binding [inference]

transcription coregulator binding [inference]

transcription coactivator binding

DNA-binding transcription factor binding [inference]

RNA polymerase II-specific DNA-binding transcription factor binding

protein dimerization activity [inference]

protein heterodimerization activity

organic cyclic compound binding [inference]

nucleic acid binding [inference]

transcription regulatory region nucleic acid binding [inference]

transcription cis-regulatory region binding [inference]

RNA polymerase II transcription regulatory region sequence-specific DNA binding

RNA polymerase II cis-regulatory region sequence-specific DNA binding

cis-regulatory region sequence-specific DNA binding [inference]

RNA polymerase II cis-regulatory region sequence-specific DNA binding

DNA binding [inference]

double-stranded DNA binding [inference]

sequence-specific double-stranded DNA binding [inference]

transcription cis-regulatory region binding [inference]

RNA polymerase II transcription regulatory region sequence-specific DNA binding

RNA polymerase II cis-regulatory region sequence-specific DNA binding

cis-regulatory region sequence-specific DNA binding [inference]

RNA polymerase II cis-regulatory region sequence-specific DNA binding

sequence-specific DNA binding

sequence-specific double-stranded DNA binding [inference]

transcription cis-regulatory region binding [inference]

RNA polymerase II transcription regulatory region sequence-specific DNA binding

RNA polymerase II cis-regulatory region sequence-specific DNA binding

cis-regulatory region sequence-specific DNA binding [inference]

RNA polymerase II cis-regulatory region sequence-specific DNA binding

transcription regulator activity [inference]

DNA-binding transcription factor activity [inference]

DNA-binding transcription factor activity, RNA polymerase II-specific

DNA-binding transcription activator activity, RNA polymerase II-specific

DNA-binding transcription activator activity [inference]

DNA-binding transcription activator activity, RNA polymerase II-specific

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

hypoxia-inducible factor 1-alpha

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
cellular response to hypoxia
protein dimerization activity

Displaying **all 9** entries
InterPro
HIF-1 alpha, C-terminal transactivation domain
Helix-loop-helix DNA-binding domain superfamily
Hypoxia-inducible factor, alpha subunit-like
Myc-type, basic helix-loop-helix (bHLH) domain
PAC motif
PAS domain superfamily
PAS domain
PAS fold-3
PAS fold

Disease

Disease Ontology

Displaying **all 4** entries
DO ID	Disease Name	Source
DOID:0080339	familial erythrocytosis 4	Alliance of Genome Resources
DOID:3908	lung non-small cell carcinoma	Alliance of Genome Resources
DOID:6432	pulmonary hypertension	Alliance of Genome Resources
DOID:8432	polycythemia	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 84 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	2034	Xenbase:XB-GENE-981612
Drosophila melanogaster	3091	FB:FBgn0266411
Caenorhabditis elegans	4861	WB:WBGene00011327
Caenorhabditis elegans	6493	WB:WBGene00011327
Mus musculus	13819		MOUSE19661
Rattus norvegicus	29452		RATNO35065
Caenorhabditis elegans	64067	WB:WBGene00011327
Bos taurus	282711		BOVIN02334
Ovis aries	443286		SHEEP13885
Pan troglodytes	459204		PANTR27540

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements