GlyCosmos Portal

GlyTouCan

Glycan Structure Repository

GlyComb

Glycoconjugate Repository

GlycoPOST

Glycomics MS raw data Repository

UniCarb-DR

Glycomics MS Repository for glycan annotations from GlycoWorkbench

LM-GlycoRepo

Repository for lectin-assisted multimodality data

All Resources

Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms

Other Information

Release Statistics Download

Tools

Glycan Converters

LM-GlycomeAtlas

Search Tools

Cross Search Glycan Search Publication Search Programmatic Access

Guidelines

MIRAGE

erythrocyte membrane protein band 4.2

Summary

Gene Symbol

EPB42

Organism

Homo sapiens (human)

External Links

NCBI Gene

2038

PubChem

2038

Alliance of Genome Resources

HGNC:3381

JoGo

EPB42

TogoVar

EPB42

Annotation

Keyword

3D-structure
Alternative splicing
Cell membrane
Cell shape
Cytoskeleton
Direct protein sequencing
Disease variant
Erythrocyte maturation
Hereditary hemolytic anemia
Myristate
Phosphoprotein
Proteomics identification
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
P16452	Erythrocyte membrane protein band 4.2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
cell morphogenesis	IEA
cytoskeleton organization	IEA
regulation of cell shape	IEA
hemoglobin metabolic process	IEA
erythrocyte maturation	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

hemoglobin metabolic process

primary metabolic process [inference]

protein metabolic process [inference]

hemoglobin metabolic process

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

hemoglobin metabolic process

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

hemoglobin metabolic process

cellular process [inference]

cellular developmental process [inference]

cell maturation [inference]

erythrocyte maturation

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization

multicellular organismal process [inference]

multicellular organismal-level homeostasis [inference]

multicellular organismal-level chemical homeostasis [inference]

multicellular organismal-level iron ion homeostasis

developmental process [inference]

anatomical structure morphogenesis [inference]

cell morphogenesis

developmental maturation [inference]

anatomical structure maturation [inference]

cell maturation [inference]

erythrocyte maturation

anatomical structure development [inference]

animal organ development [inference]

hematopoietic or lymphoid organ development [inference]

spleen development

cellular developmental process [inference]

cell maturation [inference]

erythrocyte maturation

homeostatic process [inference]

multicellular organismal-level homeostasis [inference]

multicellular organismal-level chemical homeostasis [inference]

multicellular organismal-level iron ion homeostasis

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

monoatomic cation homeostasis [inference]

multicellular organismal-level iron ion homeostasis

inorganic ion homeostasis [inference]

multicellular organismal-level iron ion homeostasis

multicellular organismal-level chemical homeostasis [inference]

multicellular organismal-level iron ion homeostasis

biological regulation [inference]

regulation of biological process [inference]

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of cell morphogenesis [inference]

regulation of cell shape

regulation of biological quality [inference]

regulation of cell shape

Displaying **all 4** entries
GO Term	Evidence Code	PMID
cytoskeleton	TAS	1350227
plasma membrane	IEA
cortical cytoskeleton	IEA
ankyrin-1 complex	IDA	35835865

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

ankyrin-1 complex

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

organelle [inference]

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cortical cytoskeleton

intracellular organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cortical cytoskeleton

Displaying **all 4** entries
GO Term	Evidence Code	PMID
protein-glutamine gamma-glutamyltransferase activity	IBA
structural constituent of cytoskeleton	TAS	1350227
protein binding	IPI	12646258 12970870 32814053
ATP binding	TAS	8608138

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

acyltransferase activity [inference]

aminoacyltransferase activity [inference]

protein-glutamine gamma-glutamyltransferase activity

catalytic activity, acting on a protein [inference]

protein-glutamine gamma-glutamyltransferase activity

structural molecule activity [inference]

structural constituent of cytoskeleton

binding [inference]

protein binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

transglutaminase

Functional Category

E: Amino acid transport and metabolism
I: Lipid transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 2** entries
Gene Ontology
metal ion binding
protein-glutamine gamma-glutamyltransferase activity

Displaying **all 9** entries
InterPro
Immunoglobulin E-set
Immunoglobulin-like fold
Papain-like cysteine peptidase superfamily
Protein-glutamine gamma-glutamyltransferase, animal
Transglutaminase, C-terminal domain superfamily
Transglutaminase, C-terminal
Transglutaminase, N-terminal
Transglutaminase-like superfamily
Transglutaminase-like

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0110920	hereditary spherocytosis type 5	Alliance of Genome Resources
DOID:12971	hereditary spherocytosis	Alliance of Genome Resources

About Release Notes Help Feedback

Click here to visit the beta site.

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

Logo License Policies Site Map

Contact: support@glycosmos.org

GlyCosmos Portal v4.4.0

Last updated: December 8, 2025