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solute carrier family 31, member 1

Summary

Gene Symbol

Slc31a1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

20529

PubChem

20529

Alliance of Genome Resources

MGI:1333843

Annotation

Keyword

Cell membrane
Copper transport
Disulfide bond
Endosome
Glycoprotein
Oxidation
Phosphoprotein
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q8K211	Copper transporter 1 Solute carrier family 31 member 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
establishment of localization in cell	IMP	12177073
vascular endothelial growth factor receptor-2 signaling pathway	ISO ISS
cellular response to cisplatin	ISO
copper ion transport	IDA	11391005
transmembrane transport	ISO

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein tyrosine kinase signaling pathway [inference]

vascular endothelial growth factor receptor signaling pathway [inference]

vascular endothelial growth factor receptor-2 signaling pathway

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to cisplatin

transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

copper ion transmembrane transport [inference]

plasma membrane copper ion transport

copper ion import across plasma membrane

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

copper ion transmembrane transport [inference]

plasma membrane copper ion transport

copper ion import across plasma membrane

inorganic cation import across plasma membrane [inference]

copper ion import across plasma membrane

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

copper ion import across plasma membrane

silver ion transmembrane transport

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

copper ion import across plasma membrane

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly [inference]

protein complex oligomerization

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

protein complex oligomerization

developmental process [inference]

anatomical structure formation involved in morphogenesis [inference]

angiogenesis

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular copper ion homeostasis

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular copper ion homeostasis

monoatomic cation homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular copper ion homeostasis

copper ion homeostasis [inference]

intracellular copper ion homeostasis

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular copper ion homeostasis

inorganic ion homeostasis [inference]

copper ion homeostasis [inference]

intracellular copper ion homeostasis

response to stimulus [inference]

response to chemical [inference]

cellular response to chemical stimulus [inference]

cellular response to cisplatin

response to cisplatin [inference]

cellular response to cisplatin

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to cisplatin

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

transition metal ion transport [inference]

copper ion transport

copper ion import

copper ion transmembrane transport [inference]

plasma membrane copper ion transport

copper ion import across plasma membrane

monoatomic cation transmembrane transport [inference]

copper ion transmembrane transport [inference]

plasma membrane copper ion transport

copper ion import across plasma membrane

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

copper ion transmembrane transport [inference]

plasma membrane copper ion transport

copper ion import across plasma membrane

xenobiotic transport

transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

copper ion transmembrane transport [inference]

plasma membrane copper ion transport

copper ion import across plasma membrane

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

copper ion transmembrane transport [inference]

plasma membrane copper ion transport

copper ion import across plasma membrane

inorganic cation import across plasma membrane [inference]

copper ion import across plasma membrane

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

copper ion import across plasma membrane

silver ion transmembrane transport

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

copper ion import across plasma membrane

import into cell [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

copper ion import across plasma membrane

establishment of localization in cell

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein tyrosine kinase signaling pathway [inference]

vascular endothelial growth factor receptor signaling pathway [inference]

vascular endothelial growth factor receptor-2 signaling pathway

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
recycling endosome	IDA	24167251
late endosome	IDA	24167251
apical plasma membrane	IDA ISO	16950140 20699218 31002737
neuronal cell body	ISO
plasma membrane	IDA ISO	28973536 31002737

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane [inference]

bounding membrane of organelle [inference]

endosome membrane [inference]

plasma membrane region [inference]

cell junction [inference]

anchoring junction [inference]

cell-cell junction [inference]

cell-cell contact zone [inference]

intercalated disc

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

cell body [inference]

neuronal cell body

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
protein binding	IPI	24167251
copper ion transmembrane transporter activity	IDA IMP ISO ISS	11391005 12177073 16847145
silver ion transmembrane transporter activity	IDA ISO	20569931
xenobiotic transmembrane transporter activity	IMP	12370430 16847145 19144690
identical protein binding	IEA ISO

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic cation transmembrane transporter activity [inference]

metal ion transmembrane transporter activity [inference]

transition metal ion transmembrane transporter activity [inference]

inorganic molecular entity transmembrane transporter activity [inference]

inorganic cation transmembrane transporter activity [inference]

metal ion transmembrane transporter activity [inference]

transition metal ion transmembrane transporter activity [inference]

xenobiotic transmembrane transporter activity

binding [inference]

protein binding

identical protein binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

copper ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

high affinity copper uptake protein 1

Functional Category

B: Chromatin structure and dynamics
I: Lipid transport and metabolism
M: Cell wall/membrane/envelope biogenesis

Displaying **all 2** entries
Gene Ontology
copper ion transport
monoatomic ion transport

Displaying 1 entry
InterPro
Ctr copper transporter

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0050700	cardiomyopathy	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of **112** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	1317		HGNC:11016	HUMAN98084
Drosophila melanogaster	31601		FB:FBgn0062413
Rattus norvegicus	171135	10116_1:00211f	RGD:620059	RATNO34106
Caenorhabditis elegans	172196		WB:WBGene00017852
Danio rerio	403028		ZFIN:ZDB-GENE-040415-3	DANRE35474
Xenopus tropicalis	407919		Xenbase:XB-GENE-994882
Pan troglodytes	464670			PANTR44629
Bos taurus	518976			BOVIN35146
Macaca mulatta	706058			MACMU12454
Saccharomyces cerevisiae S288C	851129		SGD:S000004403