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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
solute carrier family 4 (anion exchanger), member 2
Summary
- Gene Symbol
-
- Slc4a2
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Alternative splicing
- Anion exchange
- Antiport
- Cell membrane
- Glycoprotein
- Methylation
- Palmitate
- Phosphoprotein
- Proteomics identification
- Reference proteome
- Spermatogenesis
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| A0A0R4J1K4 |
|
| Q3UKP0 |
|
| P13808 |
|
| A0A0R4J1K9 |
|
| A0A0R4J101 |
|
| Q7TPS4 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| negative regulation of CD8-positive, alpha-beta T cell differentiation | ||
| amelogenesis | ||
| chloride transmembrane transport | ||
| negative regulation of CD8-positive, alpha-beta T cell proliferation | ||
| bicarbonate transport |
GO Hierarchy
biological process
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
negative regulation of immune system process [inference]
regulation of leukocyte activation [inference]
negative regulation of leukocyte activation [inference]
regulation of lymphocyte activation [inference]
negative regulation of biological process [inference]
negative regulation of immune system process [inference]
negative regulation of cellular process [inference]
negative regulation of multicellular organismal process [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of cell adhesion [inference]
regulation of cell population proliferation [inference]
regulation of cell differentiation [inference]
negative regulation of cellular process [inference]
regulation of cell activation [inference]
regulation of leukocyte activation [inference]
negative regulation of leukocyte activation [inference]
regulation of lymphocyte activation [inference]
negative regulation of cell activation [inference]
regulation of multicellular organismal process [inference]
regulation of cell activation [inference]
regulation of leukocyte activation [inference]
negative regulation of leukocyte activation [inference]
regulation of lymphocyte activation [inference]
negative regulation of cell activation [inference]
negative regulation of multicellular organismal process [inference]
regulation of multicellular organismal development [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| enzyme binding | ||
| chloride transmembrane transporter activity | ||
| transmembrane transporter activity | ||
| chloride:bicarbonate antiporter activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- Anion exchange protein
- Functional Category
-
- I: Lipid transport and metabolism
- Q: Secondary metabolites biosynthesis, transport and catabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| bicarbonate transport |
| inorganic anion transport |
| monoatomic anion transmembrane transporter activity |
| monoatomic ion transport |
| regulation of intracellular pH |
| solute |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0110861 | autosomal recessive polycystic kidney disease | |
| DOID:11716 | prediabetes syndrome | |
| DOID:13533 | osteopetrosis | |
| DOID:2355 | anemia |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 6522 | HGNC:11028 | HUMAN92070 | ||
| 24780 | 10116_1:001a63 | RGD:3711 | RATNO29426 | |
| 39147 | FB:FBgn0036043 | |||
| 180943 | WB:WBGene00019844 | |||
| 397203 | PIGXX12280 | |||
| 463890 | PANTR47452 | |||
| 475538 | CANLF04585 | |||
| 566075 | ZFIN:ZDB-GENE-051101-2 | |||
| 570716 | ZFIN:ZDB-GENE-030429-14 | DANRE25502 | ||
| 713966 | MACMU32823 |
