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solute carrier family 4 (anion exchanger), member 3

Summary

Gene Symbol

Slc4a3

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

20536

PubChem

20536

Alliance of Genome Resources

MGI:109350

Annotation

Keyword

Alternative splicing
Anion exchange
Antiport
Cell membrane
Glycoprotein
Methylation
Palmitate
Phosphoprotein
Reference proteome
Transmembrane helix

Proteins

Displaying **all 3** entries
UniProt	Protein Name
Q9ERP4
P16283	Neuronal band 3-like protein Solute carrier family 4 member 3
Q68EG4

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
chloride transmembrane transport	IEA
bicarbonate transport	IBA IEA ISO
transmembrane transport	IBA
pH reduction	ISO ISS
regulation of intracellular pH	IBA IDA	2686841

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic anion transmembrane transport [inference]

chloride transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic anion transmembrane transport [inference]

chloride transmembrane transport

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

regulation of cellular pH [inference]

regulation of intracellular pH

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

regulation of cellular pH [inference]

regulation of intracellular pH

monoatomic cation homeostasis [inference]

regulation of pH [inference]

regulation of cellular pH [inference]

regulation of intracellular pH

pH reduction

intracellular monoatomic cation homeostasis [inference]

regulation of cellular pH [inference]

regulation of intracellular pH

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

regulation of cellular pH [inference]

regulation of intracellular pH

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic anion transport [inference]

chloride transport [inference]

chloride transmembrane transport

monoatomic anion transmembrane transport [inference]

chloride transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic anion transmembrane transport [inference]

chloride transmembrane transport

inorganic anion transport [inference]

chloride transport [inference]

chloride transmembrane transport

inorganic anion transmembrane transport [inference]

chloride transmembrane transport

transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic anion transmembrane transport [inference]

chloride transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic anion transmembrane transport [inference]

chloride transmembrane transport

organic substance transport [inference]

organic anion transport [inference]

bicarbonate transport

one-carbon compound transport [inference]

bicarbonate transport

biological regulation [inference]

regulation of pH [inference]

regulation of cellular pH [inference]

regulation of intracellular pH

pH reduction

regulation of biological process [inference]

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of blood circulation [inference]

regulation of heart contraction [inference]

cardiac conduction

regulation of action potential [inference]

regulation of cardiac muscle cell action potential

regulation of biological quality [inference]

regulation of membrane potential [inference]

regulation of action potential [inference]

regulation of cardiac muscle cell action potential

regulation of intracellular pH

Displaying **all 2** entries
GO Term	Evidence Code	PMID
external side of plasma membrane	IEA ISO
plasma membrane	IBA IDA ISO	2686841

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

side of membrane [inference]

external side of plasma membrane

Displaying **all 4** entries
GO Term	Evidence Code	PMID
enzyme binding	ISO
bicarbonate transmembrane transporter activity	ISO
transmembrane transporter activity	IBA
chloride:bicarbonate antiporter activity	IDA ISO	2686841

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity

organic anion transmembrane transporter activity [inference]

bicarbonate transmembrane transporter activity

bicarbonate:monoatomic anion antiporter activity [inference]

chloride:bicarbonate antiporter activity

monoatomic ion transmembrane transporter activity [inference]

monoatomic anion transmembrane transporter activity [inference]

chloride transmembrane transporter activity [inference]

chloride:bicarbonate antiporter activity

bicarbonate:monoatomic anion antiporter activity [inference]

chloride:bicarbonate antiporter activity

active monoatomic ion transmembrane transporter activity [inference]

bicarbonate:monoatomic anion antiporter activity [inference]

chloride:bicarbonate antiporter activity

inorganic molecular entity transmembrane transporter activity [inference]

inorganic anion transmembrane transporter activity [inference]

solute:inorganic anion antiporter activity [inference]

chloride:bicarbonate antiporter activity

chloride transmembrane transporter activity [inference]

chloride:bicarbonate antiporter activity

bicarbonate transmembrane transporter activity

bicarbonate:monoatomic anion antiporter activity [inference]

chloride:bicarbonate antiporter activity

active transmembrane transporter activity [inference]

secondary active transmembrane transporter activity [inference]

antiporter activity [inference]

solute:inorganic anion antiporter activity [inference]

chloride:bicarbonate antiporter activity

bicarbonate:monoatomic anion antiporter activity [inference]

chloride:bicarbonate antiporter activity

active monoatomic ion transmembrane transporter activity [inference]

bicarbonate:monoatomic anion antiporter activity [inference]

chloride:bicarbonate antiporter activity

salt transmembrane transporter activity [inference]

bicarbonate transmembrane transporter activity

bicarbonate:monoatomic anion antiporter activity [inference]

chloride:bicarbonate antiporter activity

chloride transmembrane transporter activity [inference]

chloride:bicarbonate antiporter activity

binding [inference]

protein binding [inference]

enzyme binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

Anion exchange protein

Functional Category

F: Nucleotide transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 6** entries
Gene Ontology
bicarbonate transport
inorganic anion transport
monoatomic anion transmembrane transporter activity
monoatomic ion transport
regulation of intracellular pH
solute

Displaying **all 7** entries
InterPro
Anion exchange protein 3
Anion exchange protein
Anion exchange, conserved site
Band 3 cytoplasmic domain
Bicarbonate transporter, eukaryotic
Bicarbonate transporter-like, transmembrane domain
Phosphotransferase/anion transporter

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0050793	short QT syndrome	Alliance of Genome Resources
DOID:2355	anemia	Alliance of Genome Resources

Ortholog

Displaying entries **21 - 30** of 99 in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Cricetulus griseus	100767310	10029_0:001bd6	CRIGR20826
Sarcophilus harrisii	100930777		SARHA07457
Pan paniscus	100974117		PANPA26748
Papio anubis	101013641		PAPAN01799
Saimiri boliviensis boliviensis	101044586		SAIBB09332
Takifugu rubripes	101061999		TAKRU24566
Felis catus	101098649		FELCA19879
Gorilla gorilla gorilla	101147193		GORGO26586
Tursiops truncatus	101321124		TURTR07200
Octodon degus	101562092	10160_0:002e97	OCTDE16372

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OrthoDB (Group)

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Acknowledgements