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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Rous sarcoma oncogene
Summary
- Gene Symbol
-
- Src
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Alternative splicing
- Cell adhesion
- Cell cycle
- Cell junction
- Cell membrane
- Cytoskeleton
- Immunity
- Mitochondrion inner membrane
- Myristate
- Nucleus
- Phosphoprotein
- Proto-oncogene
- Reference proteome
- SH2 domain
- SH3 domain
- Tyrosine-protein kinase
- Ubl conjugation
- Proteins
| UniProt | Protein Name |
|---|---|
| P05480 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| cellular response to fluid shear stress | ||
| positive regulation of small GTPase mediated signal transduction | ||
| positive regulation of gene expression | ||
| cellular response to transforming growth factor beta stimulus | ||
| negative regulation of extrinsic apoptotic signaling pathway |
GO Hierarchy
- positive regulation of cell adhesion
- positive regulation of cell adhesion
biological process
metabolic process [inference]
cellular process [inference]
developmental process [inference]
response to stimulus [inference]
response to endogenous stimulus [inference]
response to chemical [inference]
cellular response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of cellular metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of phosphorus metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of nitrogen compound metabolic process [inference]
regulation of protein metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of macromolecule biosynthetic process [inference]
negative regulation of macromolecule metabolic process [inference]
regulation of DNA metabolic process [inference]
regulation of protein metabolic process [inference]
regulation of small molecule metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
regulation of protein metabolic process [inference]
regulation of signaling [inference]
regulation of signal transduction [inference]
positive regulation of signaling [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
positive regulation of metabolic process [inference]
positive regulation of signaling [inference]
positive regulation of cellular process [inference]
positive regulation of cell communication [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of response to stimulus [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of signal transduction [inference]
positive regulation of response to stimulus [inference]
regulation of cellular process [inference]
signal transduction [inference]
regulation of cell communication [inference]
regulation of signal transduction [inference]
positive regulation of cell communication [inference]
regulation of cell adhesion [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of cellular metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of phosphorus metabolic process [inference]
regulation of cell population proliferation [inference]
regulation of programmed cell death [inference]
regulation of cellular component biogenesis [inference]
positive regulation of cellular process [inference]
positive regulation of cell communication [inference]
positive regulation of cellular metabolic process [inference]
negative regulation of cellular process [inference]
regulation of cellular component organization [inference]
regulation of cellular localization [inference]
regulation of molecular function [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| actin filament | ||
| nucleoplasm | ||
| dendritic filopodium | ||
| mitochondrion | ||
| lysosome |
| GO Term | Evidence Code | PMID |
|---|---|---|
| kinase activity | ||
| protein binding | ||
| integrin binding | ||
| phospholipase activator activity | ||
| phosphoprotein binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- proto-oncogene tyrosine-protein kinase Src
- Functional Category
-
- K: Transcription
- T: Signal transduction mechanisms
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060074 | ductal carcinoma in situ | |
| DOID:0080199 | colorectal carcinoma | |
| DOID:0080855 | Parkinsonism | |
| DOID:10155 | intestinal cancer | |
| DOID:10283 | prostate cancer | |
| DOID:10534 | stomach cancer | |
| DOID:10763 | hypertension | |
| DOID:1520 | colon carcinoma | |
| DOID:1588 | thrombocytopenia | |
| DOID:162 | cancer |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 108519844 | RHIBE08388 | |||
| 109313187 | CROPO22596 | |||
| 109702281 | 51338_0:0045da | |||
| 110211455 | PHACI21159 | |||
| 110310031 | 10089_0:0004d3 | |||
| 110317793 | 10093_0:000f2c | |||
| 110566227 | 10047_0:0006bf | |||
| 112928171 | VULVU22785 | |||
| 113178881 | 9999_0:000790 | |||
| 113434410 | PSETE05118 |
