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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Rous sarcoma oncogene
Summary
- Gene Symbol
-
- Src
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Alternative splicing
- Cell adhesion
- Cell cycle
- Cell junction
- Cell membrane
- Cytoskeleton
- Immunity
- Mitochondrion inner membrane
- Myristate
- Nucleus
- Phosphoprotein
- Proto-oncogene
- Reference proteome
- SH2 domain
- SH3 domain
- Tyrosine-protein kinase
- Ubl conjugation
- Proteins
| UniProt | Protein Name |
|---|---|
| P05480 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| epidermal growth factor receptor signaling pathway | ||
| positive regulation of protein transport | ||
| positive regulation of TORC1 signaling | ||
| negative regulation of gene expression | ||
| cellular response to prolactin |
GO Hierarchy
- positive regulation of cell adhesion
- positive regulation of cell adhesion
biological process
metabolic process [inference]
cellular process [inference]
developmental process [inference]
response to stimulus [inference]
response to endogenous stimulus [inference]
response to chemical [inference]
cellular response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of cellular metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of phosphorus metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of nitrogen compound metabolic process [inference]
regulation of protein metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of macromolecule biosynthetic process [inference]
negative regulation of macromolecule metabolic process [inference]
regulation of DNA metabolic process [inference]
regulation of protein metabolic process [inference]
regulation of small molecule metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
regulation of protein metabolic process [inference]
regulation of signaling [inference]
regulation of signal transduction [inference]
positive regulation of signaling [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
positive regulation of metabolic process [inference]
positive regulation of signaling [inference]
positive regulation of cellular process [inference]
positive regulation of cell communication [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of response to stimulus [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of signal transduction [inference]
positive regulation of response to stimulus [inference]
regulation of cellular process [inference]
signal transduction [inference]
regulation of cell communication [inference]
regulation of signal transduction [inference]
positive regulation of cell communication [inference]
regulation of cell adhesion [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of cellular metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of phosphorus metabolic process [inference]
regulation of cell population proliferation [inference]
regulation of programmed cell death [inference]
regulation of cellular component biogenesis [inference]
positive regulation of cellular process [inference]
positive regulation of cell communication [inference]
positive regulation of cellular metabolic process [inference]
negative regulation of cellular process [inference]
regulation of cellular component organization [inference]
regulation of cellular localization [inference]
regulation of molecular function [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| cell junction | ||
| membrane | ||
| postsynaptic specialization, intracellular component | ||
| focal adhesion | ||
| late endosome |
| GO Term | Evidence Code | PMID |
|---|---|---|
| kinase activity | ||
| protein binding | ||
| integrin binding | ||
| phospholipase activator activity | ||
| phosphoprotein binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- proto-oncogene tyrosine-protein kinase Src
- Functional Category
-
- K: Transcription
- T: Signal transduction mechanisms
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:1824 | status epilepticus | |
| DOID:1928 | Williams-Beuren syndrome | |
| DOID:219 | colon cancer | |
| DOID:2316 | brain ischemia | |
| DOID:234 | colon adenocarcinoma | |
| DOID:2907 | Goldenhar syndrome | |
| DOID:305 | carcinoma | |
| DOID:3907 | lung squamous cell carcinoma | |
| DOID:3910 | lung adenocarcinoma | |
| DOID:557 | kidney disease |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 535742 | BOVIN05223 | |||
| 701057 | MACMU01707 | |||
| 100029391 | MONDO08755 | |||
| 100069870 | HORSE21674 | |||
| 100154503 | PIGXX11725 | |||
| 100227812 | TAEGU12534 | |||
| 100230630 | TAEGU12534 | |||
| 100386165 | CALJA34949 | |||
| 100436498 | PONAB20372 | |||
| 100474271 | AILME16930 |
