GlyCosmos Portal

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GO Term	Evidence Code	PMID
kinase activity	IMP	12808090
protein binding	IPI	10220404 11274221 11826110 14593208 14600260 14739300 16267818 16298995 16407161 16990796 17000758 18289379 18560762 18691334 19122674 19920076 20847314 21199370 21266176 21282606 21525037 22439932 24190966 28054552 7518772 8861907
integrin binding	IEA ISO
phospholipase activator activity	IEA ISO
phosphoprotein binding	IEA ISO

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity

protein kinase activity

protein tyrosine kinase activity

non-membrane spanning protein tyrosine kinase activity

phosphotransferase activity, alcohol group as acceptor [inference]

protein kinase activity

protein tyrosine kinase activity

non-membrane spanning protein tyrosine kinase activity

catalytic activity, acting on a protein [inference]

protein kinase activity

protein tyrosine kinase activity

non-membrane spanning protein tyrosine kinase activity

binding [inference]

protein binding

signaling receptor binding

receptor serine/threonine kinase binding [inference]

transmembrane receptor protein serine/threonine kinase binding [inference]

BMP receptor binding

ephrin receptor binding

transcription factor binding [inference]

DNA-binding transcription factor binding [inference]

RNA polymerase II-specific DNA-binding transcription factor binding [inference]

nuclear receptor binding [inference]

nuclear estrogen receptor binding

enzyme binding

kinase binding [inference]

protein kinase binding

protein kinase C binding

phospholipase binding

protein domain specific binding

SH2 domain binding

transmembrane transporter binding

cell adhesion molecule binding

integrin binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

protein-containing complex binding

integrin binding

organic cyclic compound binding [inference]

tetrapyrrole binding [inference]

heme binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme activator activity [inference]

lipase activator activity [inference]

phospholipase activator activity

molecular function activator activity [inference]

enzyme activator activity [inference]

lipase activator activity [inference]

phospholipase activator activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

proto-oncogene tyrosine-protein kinase Src

Functional Category

K: Transcription
T: Signal transduction mechanisms

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Gene Ontology
ATP binding
bone resorption
epidermal growth factor receptor signaling pathway
kinase activity
negative regulation of extrinsic apoptotic signaling pathway
negative regulation of intrinsic apoptotic signaling pathway
non-membrane spanning protein tyrosine kinase activity
nucleotide binding
osteoclast development
phosphorylation

Displaying **all 10** entries
InterPro
Protein kinase domain
Protein kinase, ATP binding site
Protein kinase-like domain superfamily
SH2 domain superfamily
SH2 domain
SH3 domain
SH3-like domain superfamily
Serine-threonine/tyrosine-protein kinase, catalytic domain
Tyrosine-protein kinase, active site
Tyrosine-protein kinase, catalytic domain

Disease

Disease Ontology

Displaying entries **11 - 20** of 25 in total

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DO ID	Disease Name	Source
DOID:1824	status epilepticus	Alliance of Genome Resources
DOID:1928	Williams-Beuren syndrome	Alliance of Genome Resources
DOID:219	colon cancer	Alliance of Genome Resources
DOID:2316	brain ischemia	Alliance of Genome Resources
DOID:234	colon adenocarcinoma	Alliance of Genome Resources
DOID:2907	Goldenhar syndrome	Alliance of Genome Resources
DOID:305	carcinoma	Alliance of Genome Resources
DOID:3907	lung squamous cell carcinoma	Alliance of Genome Resources
DOID:3910	lung adenocarcinoma	Alliance of Genome Resources
DOID:557	kidney disease	Alliance of Genome Resources

Ortholog

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Peromyscus eremicus	131909890	42410_0:001bc4

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements