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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Rous sarcoma oncogene
Summary
- Gene Symbol
-
- Src
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Alternative splicing
- Cell adhesion
- Cell cycle
- Cell junction
- Cell membrane
- Cytoskeleton
- Immunity
- Mitochondrion inner membrane
- Myristate
- Nucleus
- Phosphoprotein
- Proto-oncogene
- Reference proteome
- SH2 domain
- SH3 domain
- Tyrosine-protein kinase
- Ubl conjugation
- Proteins
| UniProt | Protein Name |
|---|---|
| P05480 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| negative regulation of transcription by RNA polymerase II | ||
| response to mechanical stimulus | ||
| focal adhesion assembly | ||
| regulation of cell-cell adhesion | ||
| protein destabilization |
GO Hierarchy
- positive regulation of cell adhesion
- positive regulation of cell adhesion
biological process
metabolic process [inference]
cellular process [inference]
developmental process [inference]
response to stimulus [inference]
response to endogenous stimulus [inference]
response to chemical [inference]
cellular response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of cellular metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of phosphorus metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of nitrogen compound metabolic process [inference]
regulation of protein metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of macromolecule biosynthetic process [inference]
negative regulation of macromolecule metabolic process [inference]
regulation of DNA metabolic process [inference]
regulation of protein metabolic process [inference]
regulation of small molecule metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
regulation of protein metabolic process [inference]
regulation of signaling [inference]
regulation of signal transduction [inference]
positive regulation of signaling [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
positive regulation of metabolic process [inference]
positive regulation of signaling [inference]
positive regulation of cellular process [inference]
positive regulation of cell communication [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of response to stimulus [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of signal transduction [inference]
positive regulation of response to stimulus [inference]
regulation of cellular process [inference]
signal transduction [inference]
regulation of cell communication [inference]
regulation of signal transduction [inference]
positive regulation of cell communication [inference]
regulation of cell adhesion [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of cellular metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of phosphorus metabolic process [inference]
regulation of cell population proliferation [inference]
regulation of programmed cell death [inference]
regulation of cellular component biogenesis [inference]
positive regulation of cellular process [inference]
positive regulation of cell communication [inference]
positive regulation of cellular metabolic process [inference]
negative regulation of cellular process [inference]
regulation of cellular component organization [inference]
regulation of cellular localization [inference]
regulation of molecular function [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| cell junction | ||
| membrane | ||
| postsynaptic specialization, intracellular component | ||
| focal adhesion | ||
| late endosome |
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein kinase binding | ||
| transmembrane transporter binding | ||
| non-membrane spanning protein tyrosine kinase activity | ||
| protein domain specific binding | ||
| BMP receptor binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- proto-oncogene tyrosine-protein kinase Src
- Functional Category
-
- K: Transcription
- T: Signal transduction mechanisms
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060074 | ductal carcinoma in situ | |
| DOID:0080199 | colorectal carcinoma | |
| DOID:0080855 | Parkinsonism | |
| DOID:10155 | intestinal cancer | |
| DOID:10283 | prostate cancer | |
| DOID:10534 | stomach cancer | |
| DOID:10763 | hypertension | |
| DOID:1520 | colon carcinoma | |
| DOID:1588 | thrombocytopenia | |
| DOID:162 | cancer |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 101065281 | TAKRU37875 | |||
| 101103084 | SHEEP04670 | |||
| 101153251 | GORGO21954 | |||
| 101164480 | ORYLA16156 | |||
| 101330307 | TURTR00767 | |||
| 101588338 | 10160_0:0018b1 | OCTDE08688 | ||
| 101612010 | 51337_0:002abe | JACJA18447 | ||
| 101703827 | 10181_0:003faf | |||
| 101809008 | FICAL08211 | |||
| 101834139 | 10036_0:003e54 |
