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AKT serine/threonine kinase 1
Summary
- Gene Symbol
-
- AKT1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Acetylation
- Alternative splicing
- Apoptosis
- Cell membrane
- Cytoplasm
- Developmental protein
- Disease variant
- Disulfide bond
- Glucose metabolism
- Glycogen biosynthesis
- Glycogen metabolism
- Glycoprotein
- Isopeptide bond
- Mitochondrion
- Neurogenesis
- Nucleus
- Phosphoprotein
- Proto-oncogene
- Reference proteome
- Serine/threonine-protein kinase
- Sugar transport
- Translation regulation
- Ubl conjugation
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| response to growth factor | ||
| positive regulation of glucose metabolic process | ||
| non-canonical NF-kappaB signal transduction | ||
| positive regulation of endothelial cell migration | ||
| regulation of type B pancreatic cell development |
GO Hierarchy
- regulation of translation
- regulation of translation
- regulation of translation
- positive regulation of cell growth
- regulation of myelination
- positive regulation of cell growth
biological process
metabolic process [inference]
nitrogen compound metabolic process [inference]
biosynthetic process [inference]
cellular metabolic process [inference]
primary metabolic process [inference]
organic substance metabolic process [inference]
cellular process [inference]
biological process involved in interspecies interaction between organisms [inference]
response to stimulus [inference]
response to endogenous stimulus [inference]
response to chemical [inference]
cellular response to stimulus [inference]
localization [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of biosynthetic process [inference]
regulation of cellular biosynthetic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of phosphorus metabolic process [inference]
positive regulation of nitrogen compound metabolic process [inference]
regulation of catabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of cellular metabolic process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of phosphorus metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of phosphorus metabolic process [inference]
positive regulation of phosphorus metabolic process [inference]
regulation of phosphate metabolic process [inference]
regulation of phosphorylation [inference]
regulation of protein phosphorylation [inference]
positive regulation of phosphorylation [inference]
regulation of kinase activity [inference]
positive regulation of phosphate metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of nitrogen compound metabolic process [inference]
regulation of protein metabolic process [inference]
regulation of proteolysis [inference]
regulation of protein modification process [inference]
positive regulation of protein metabolic process
regulation of macromolecule metabolic process [inference]
regulation of macromolecule biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
regulation of protein metabolic process [inference]
regulation of proteolysis [inference]
regulation of protein modification process [inference]
positive regulation of protein metabolic process
regulation of primary metabolic process [inference]
regulation of lipid metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
regulation of protein metabolic process [inference]
regulation of proteolysis [inference]
regulation of protein modification process [inference]
positive regulation of protein metabolic process
regulation of signaling [inference]
regulation of signal transduction [inference]
negative regulation of signaling [inference]
regulation of localization [inference]
regulation of transport [inference]
regulation of cellular localization [inference]
regulation of locomotion [inference]
positive regulation of biological process [inference]
positive regulation of metabolic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of phosphorus metabolic process [inference]
positive regulation of nitrogen compound metabolic process [inference]
positive regulation of cellular process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of phosphorus metabolic process [inference]
positive regulation of cell cycle [inference]
positive regulation of protein localization [inference]
negative regulation of biological process [inference]
negative regulation of metabolic process [inference]
negative regulation of signaling [inference]
negative regulation of cellular process [inference]
negative regulation of response to stimulus [inference]
regulation of response to stimulus [inference]
regulation of signal transduction [inference]
negative regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
signal transduction
regulation of cell communication [inference]
regulation of signal transduction [inference]
negative regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of cellular metabolic process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of phosphorus metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of phosphorus metabolic process [inference]
positive regulation of phosphorus metabolic process [inference]
regulation of phosphate metabolic process [inference]
regulation of phosphorylation [inference]
regulation of protein phosphorylation [inference]
positive regulation of phosphorylation [inference]
regulation of kinase activity [inference]
positive regulation of phosphate metabolic process [inference]
regulation of transmembrane transport [inference]
regulation of programmed cell death [inference]
positive regulation of cellular process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of phosphorus metabolic process [inference]
positive regulation of cell cycle [inference]
positive regulation of protein localization [inference]
negative regulation of cellular process [inference]
regulation of cellular component organization [inference]
regulation of cell cycle [inference]
regulation of cellular localization [inference]
regulation of cell motility [inference]
regulation of molecular function [inference]
positive regulation of molecular function [inference]
regulation of catalytic activity [inference]
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| kinase activity | ||
| 14-3-3 protein binding | ||
| protein homodimerization activity | ||
| enzyme binding | ||
| nitric-oxide synthase regulator activity |
GO Hierarchy
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:684 | hepatocellular carcinoma | |
| DOID:7575 | pancreatic intraductal papillary-mucinous neoplasm | |
| DOID:8552 | chronic myeloid leukemia | |
| DOID:8719 | in situ carcinoma | |
| DOID:8805 | intermediate coronary syndrome | |
| DOID:8947 | diabetic retinopathy | |
| DOID:9256 | colorectal cancer | |
| DOID:9352 | type 2 diabetes mellitus |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 100081473 | ORNAN12431 | ||
| 100917987 | SARHA17699 | ||
| 100404447 | CALJA00754 | ||
| 105596769 | CERAT09193 | ||
| 697747 | MACMU39942 | ||
| 105489842 | MACNE41517 | ||
| 101000402 | PAPAN38149 | ||
| 129526696 | GORGO08772 | ||
| 100969444 | PANPA12824 | ||
| 740898 | PANTR09666 |
