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laccase domain containing 1

Summary

Gene Symbol

Lacc1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

210808

PubChem

210808

Alliance of Genome Resources

MGI:2445077

Annotation

Keyword

Acetylation
Cytoplasm
Endoplasmic reticulum
Hydrolase
Inflammatory response
Innate immunity
Metal-binding
Nucleus
Peroxisome
Phosphoprotein
Reference proteome
Transferase
Zinc

Proteins

Displaying 1 entry
UniProt	Protein Name
Q8BZT9	Adenosine deaminase LACC1 Fatty acid metabolism-immunity nexus Guanosine phosphorylase LACC1 Laccase domain-containing protein 1 S-methyl-5'-thioadenosine phosphorylase LACC1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **6 - 9** of 9 in total

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1

2
GO Term	Evidence Code	PMID
regulation of cellular pH	ISO
regulation of inflammatory response	IMP	30510070
nucleotide-binding oligomerization domain containing 2 signaling pathway	ISO
regulation of purine nucleotide metabolic process	IMP	31978345

GO Hierarchy

biological process

immune system process

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

immune response [inference]

innate immune response

cellular process [inference]

signal transduction [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

intracellular receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

regulation of cellular pH

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

regulation of cellular pH

monoatomic cation homeostasis [inference]

regulation of pH [inference]

regulation of cellular pH

intracellular monoatomic cation homeostasis [inference]

regulation of cellular pH

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

regulation of cellular pH

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

defense response to other organism [inference]

innate immune response

immune response [inference]

innate immune response

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response

biological regulation [inference]

regulation of pH [inference]

regulation of cellular pH

regulation of biological process [inference]

regulation of immune system process [inference]

positive regulation of immune system process [inference]

positive regulation of immune effector process [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

regulation of immune effector process [inference]

positive regulation of immune effector process [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of immune response [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of purine nucleotide metabolic process

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of phosphorus metabolic process [inference]

regulation of phosphate metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of purine nucleotide metabolic process

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of purine nucleotide metabolic process

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of small molecule metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of purine nucleotide metabolic process

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of purine nucleotide metabolic process

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of immune effector process [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of response to stimulus [inference]

positive regulation of response to biotic stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of defense response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of response to external stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

regulation of response to stimulus [inference]

regulation of response to biotic stimulus [inference]

positive regulation of response to biotic stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

regulation of response to external stimulus [inference]

positive regulation of response to external stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

regulation of inflammatory response

positive regulation of response to stimulus [inference]

positive regulation of response to biotic stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of defense response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of response to external stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

regulation of immune response [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

regulation of response to stress [inference]

regulation of defense response [inference]

positive regulation of defense response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

regulation of inflammatory response

regulation of cellular process [inference]

signal transduction [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

intracellular receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of purine nucleotide metabolic process

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of phosphorus metabolic process [inference]

regulation of phosphate metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of purine nucleotide metabolic process

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

Displaying **all 4** entries
GO Term	Evidence Code	PMID
nucleus	IDA	30510070
endoplasmic reticulum	ISO
cytoplasm	IDA	30510070
peroxisome	ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

microbody [inference]

peroxisome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

microbody [inference]

peroxisome

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
adenosine deaminase activity	ISO
guanosine phosphorylase activity	ISO
2'-deoxyadenosine deaminase activity	IEA
hydrolase activity	IEA
transferase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity

glycosyltransferase activity [inference]

pentosyltransferase activity [inference]

purine-nucleoside phosphorylase activity

S-methyl-5-thioadenosine phosphorylase activity

guanosine phosphorylase activity

hydrolase activity

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [inference]

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines [inference]

deaminase activity [inference]

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

transition metal ion binding [inference]

copper ion binding

Gene Ontology information from NCBI Gene and UniProt.

Rhea

RHEA:13233

guanosine + phosphate

guanine + α-D-ribose 1-phosphate

Enzyme

PMID

RHEA:24408

H₂O + H⁺ + adenosine

inosine + NH₄⁺

Enzyme

3.5.4.4

PMID

RHEA:19805

a purine D-ribonucleoside + phosphate

a purine nucleobase + α-D-ribose 1-phosphate

Enzyme

2.4.2.1

PMID

RHEA:27738

2'-deoxyguanosine + phosphate

guanine + 2-deoxy-α-D-ribose 1-phosphate

Enzyme

2.4.2.1

PMID

RHEA:27750

2'-deoxyinosine + phosphate

hypoxanthine + 2-deoxy-α-D-ribose 1-phosphate

Enzyme

2.4.2.1

PMID

RHEA:27642

adenosine + phosphate

adenine + α-D-ribose 1-phosphate

Enzyme

2.4.2.1

PMID

27941785

RHEA:36431

a purine 2'-deoxy-D-ribonucleoside + phosphate

a purine nucleobase + 2-deoxy-α-D-ribose 1-phosphate

Enzyme

2.4.2.1

PMID

RHEA:27638

xanthosine + phosphate

xanthine + α-D-ribose 1-phosphate

Enzyme

2.4.2.1

PMID

27941785

RHEA:27646

inosine + phosphate

hypoxanthine + α-D-ribose 1-phosphate

Enzyme

2.4.2.1

PMID

RHEA:11852

S-methyl-5'-thioadenosine + phosphate

adenine + S-methyl-5-thio-α-D-ribose 1-phosphate

Enzyme

2.4.2.28

PMID

RHEA:28190

H₂O + H⁺ + 2'-deoxyadenosine

NH₄⁺ + 2'-deoxyinosine

Enzyme

3.5.4.4

PMID

RHEA:24869

5'-deoxyadenosine + phosphate

adenine + 5-deoxy-α-D-ribose 1-phosphate

Enzyme

2.4.2.28

PMID

6164373

RHEA:27742

2'-deoxyadenosine + phosphate

adenine + 2-deoxy-α-D-ribose 1-phosphate

Enzyme

2.4.2.1

PMID

21672603

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:676	juvenile rheumatoid arthritis	Alliance of Genome Resources

Ortholog

Displaying entries **41 - 50** of 88 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Ovis aries	101109625		SHEEP02044
Oryctolagus cuniculus	100340493		RABIT12457
Dipodomys ordii	105982025		DIPOR00162
Cricetulus griseus	100769755		CRIGR07247
Rattus norvegicus	313790	RGD:1310185	RATNO09438
Cavia porcellus	100714334		CAVPO04045
Octodon degus	101585379		OCTDE18499
Melopsittacus undulatus	101874011		MELUD10724
Monodelphis domestica	100011850		MONDO32360
Pelodiscus sinensis	102445427		PELSI11222

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

International Collaboration

Acknowledgements