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laccase domain containing 1

Summary

Gene Symbol

Lacc1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

210808

PubChem

210808

Alliance of Genome Resources

MGI:2445077

Annotation

Keyword

Acetylation
Cytoplasm
Endoplasmic reticulum
Hydrolase
Inflammatory response
Innate immunity
Metal-binding
Nucleus
Peroxisome
Phosphoprotein
Reference proteome
Transferase
Zinc

Proteins

Displaying 1 entry
UniProt	Protein Name
Q8BZT9	Adenosine deaminase LACC1 Fatty acid metabolism-immunity nexus Guanosine phosphorylase LACC1 Laccase domain-containing protein 1 S-methyl-5'-thioadenosine phosphorylase LACC1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

1

2

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GO Term	Evidence Code	PMID
immune system process	IEA
pattern recognition receptor signaling pathway	ISO
inflammatory response	IEA
innate immune response	IEA
positive regulation of cytokine production involved in immune response	ISO

GO Hierarchy

biological process

immune system process

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

immune response [inference]

innate immune response

cellular process [inference]

signal transduction [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

intracellular receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

regulation of cellular pH

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

regulation of cellular pH

monoatomic cation homeostasis [inference]

regulation of pH [inference]

regulation of cellular pH

intracellular monoatomic cation homeostasis [inference]

regulation of cellular pH

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

regulation of cellular pH

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

defense response to other organism [inference]

innate immune response

immune response [inference]

innate immune response

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response

biological regulation [inference]

regulation of pH [inference]

regulation of cellular pH

regulation of biological process [inference]

regulation of immune system process [inference]

positive regulation of immune system process [inference]

positive regulation of immune effector process [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

regulation of immune effector process [inference]

positive regulation of immune effector process [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of immune response [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of purine nucleotide metabolic process

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of phosphorus metabolic process [inference]

regulation of phosphate metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of purine nucleotide metabolic process

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of purine nucleotide metabolic process

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of small molecule metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of purine nucleotide metabolic process

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of purine nucleotide metabolic process

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of immune effector process [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of response to stimulus [inference]

positive regulation of response to biotic stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of defense response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of response to external stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

regulation of response to stimulus [inference]

regulation of response to biotic stimulus [inference]

positive regulation of response to biotic stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

regulation of response to external stimulus [inference]

positive regulation of response to external stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

regulation of inflammatory response

positive regulation of response to stimulus [inference]

positive regulation of response to biotic stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of defense response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of response to external stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

regulation of immune response [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

regulation of response to stress [inference]

regulation of defense response [inference]

positive regulation of defense response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

regulation of inflammatory response

regulation of cellular process [inference]

signal transduction [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

intracellular receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [inference]

nucleotide-binding oligomerization domain containing signaling pathway [inference]

nucleotide-binding oligomerization domain containing 2 signaling pathway

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of purine nucleotide metabolic process

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of phosphorus metabolic process [inference]

regulation of phosphate metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of purine nucleotide metabolic process

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

Displaying **all 4** entries
GO Term	Evidence Code	PMID
nucleus	IDA	30510070
endoplasmic reticulum	ISO
cytoplasm	IDA	30510070
peroxisome	ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

microbody [inference]

peroxisome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

microbody [inference]

peroxisome

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GO Term	Evidence Code	PMID
purine-nucleoside phosphorylase activity	ISO
copper ion binding	IBA
S-methyl-5-thioadenosine phosphorylase activity	ISO
metal ion binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity

glycosyltransferase activity [inference]

pentosyltransferase activity [inference]

purine-nucleoside phosphorylase activity

S-methyl-5-thioadenosine phosphorylase activity

guanosine phosphorylase activity

hydrolase activity

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [inference]

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines [inference]

deaminase activity [inference]

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

transition metal ion binding [inference]

copper ion binding

Gene Ontology information from NCBI Gene and UniProt.

Rhea

RHEA:13233

guanosine + phosphate

guanine + α-D-ribose 1-phosphate

Enzyme

PMID

RHEA:24408

H₂O + H⁺ + adenosine

inosine + NH₄⁺

Enzyme

3.5.4.4

PMID

RHEA:19805

a purine D-ribonucleoside + phosphate

a purine nucleobase + α-D-ribose 1-phosphate

Enzyme

2.4.2.1

PMID

RHEA:27738

2'-deoxyguanosine + phosphate

guanine + 2-deoxy-α-D-ribose 1-phosphate

Enzyme

2.4.2.1

PMID

RHEA:27750

2'-deoxyinosine + phosphate

hypoxanthine + 2-deoxy-α-D-ribose 1-phosphate

Enzyme

2.4.2.1

PMID

RHEA:27642

adenosine + phosphate

adenine + α-D-ribose 1-phosphate

Enzyme

2.4.2.1

PMID

27941785

RHEA:36431

a purine 2'-deoxy-D-ribonucleoside + phosphate

a purine nucleobase + 2-deoxy-α-D-ribose 1-phosphate

Enzyme

2.4.2.1

PMID

RHEA:27638

xanthosine + phosphate

xanthine + α-D-ribose 1-phosphate

Enzyme

2.4.2.1

PMID

27941785

RHEA:27646

inosine + phosphate

hypoxanthine + α-D-ribose 1-phosphate

Enzyme

2.4.2.1

PMID

RHEA:11852

S-methyl-5'-thioadenosine + phosphate

adenine + S-methyl-5-thio-α-D-ribose 1-phosphate

Enzyme

2.4.2.28

PMID

RHEA:28190

H₂O + H⁺ + 2'-deoxyadenosine

NH₄⁺ + 2'-deoxyinosine

Enzyme

3.5.4.4

PMID

RHEA:24869

5'-deoxyadenosine + phosphate

adenine + 5-deoxy-α-D-ribose 1-phosphate

Enzyme

2.4.2.28

PMID

6164373

RHEA:27742

2'-deoxyadenosine + phosphate

adenine + 2-deoxy-α-D-ribose 1-phosphate

Enzyme

2.4.2.1

PMID

21672603

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:676	juvenile rheumatoid arthritis	Alliance of Genome Resources

Ortholog

Displaying entries **21 - 30** of 88 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Macaca nemestrina	105491710		MACNE36672
Papio anubis	101000474		PAPAN11088
Mandrillus leucophaeus	105535507		MANLE12116
Gorilla gorilla gorilla	101135969		GORGO06983
Pan paniscus	100981800		PANPA29539
Pan troglodytes	452569		PANTR07695
Pongo abelii	100442826		PONAB06670
Homo sapiens	144811	HGNC:26789	HUMAN16894
Canis lupus familiaris	476928		CANLF08714
Ailuropoda melanoleuca	100479470		AILME17100

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

International Collaboration

Acknowledgements