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solute carrier family 66 member 1

Summary

Gene Symbol

Slc66a1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

212555

PubChem

212555

Alliance of Genome Resources

MGI:2384837

Annotation

Keyword

Alternative splicing
Amino-acid transport
Glycoprotein
Lysosome
Reference proteome
Repeat
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q8C4N4	PQ-loop repeat-containing protein 2 Solute carrier family 66 member 1
A6PWV7

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
lysine transport	ISO ISS
L-arginine transmembrane transport	ISO ISS
intracellular amino acid homeostasis	ISO ISS
L-histidine transmembrane transport	ISO
L-lysine transmembrane transport	IEA ISO

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport [inference]

azole transmembrane transport [inference]

L-histidine transmembrane transport

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular amino acid homeostasis

chemical homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular amino acid homeostasis

localization [inference]

establishment of localization [inference]

transport [inference]

transmembrane transport [inference]

azole transmembrane transport [inference]

L-histidine transmembrane transport

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

organic substance transport [inference]

organic anion transport [inference]

carboxylic acid transport [inference]

amino acid transport [inference]

amino acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

aromatic amino acid transport [inference]

L-histidine transmembrane transport

basic amino acid transport [inference]

lysine transport

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

L-amino acid transport [inference]

L-lysine transport [inference]

L-alpha-amino acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

organic acid transport [inference]

carboxylic acid transport [inference]

amino acid transport [inference]

amino acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

aromatic amino acid transport [inference]

L-histidine transmembrane transport

basic amino acid transport [inference]

lysine transport

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

L-amino acid transport [inference]

L-lysine transport [inference]

L-alpha-amino acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

azole transmembrane transport [inference]

L-histidine transmembrane transport

modified amino acid transport [inference]

L-arginine transmembrane transport

nitrogen compound transport [inference]

amino acid transport [inference]

amino acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

aromatic amino acid transport [inference]

L-histidine transmembrane transport

basic amino acid transport [inference]

lysine transport

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

L-amino acid transport [inference]

L-lysine transport [inference]

L-alpha-amino acid transmembrane transport [inference]

azole transmembrane transport [inference]

L-histidine transmembrane transport

modified amino acid transport [inference]

L-arginine transmembrane transport

Displaying **all 3** entries
GO Term	Evidence Code	PMID
intracellular membrane-bounded organelle	ISO
organelle membrane	ISO ISS
lysosomal membrane	IBA ISO ISS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane

bounding membrane of organelle [inference]

vacuolar membrane [inference]

lytic vacuole membrane [inference]

lysosomal membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle

intracellular organelle [inference]

intracellular membrane-bounded organelle

Displaying **all 4** entries
GO Term	Evidence Code	PMID
L-arginine transmembrane transporter activity	ISO ISS
L-lysine transmembrane transporter activity	IBA ISO ISS
L-histidine transmembrane transporter activity	ISO
basic amino acid transmembrane transporter activity	ISO ISS

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

organic acid transmembrane transporter activity [inference]

carboxylic acid transmembrane transporter activity [inference]

amino acid transmembrane transporter activity [inference]

aromatic amino acid transmembrane transporter activity [inference]

L-histidine transmembrane transporter activity

basic amino acid transmembrane transporter activity

L-amino acid transmembrane transporter activity [inference]

organic anion transmembrane transporter activity [inference]

carboxylic acid transmembrane transporter activity [inference]

amino acid transmembrane transporter activity [inference]

aromatic amino acid transmembrane transporter activity [inference]

L-histidine transmembrane transporter activity

basic amino acid transmembrane transporter activity

L-amino acid transmembrane transporter activity [inference]

modified amino acid transmembrane transporter activity [inference]

L-arginine transmembrane transporter activity

azole transmembrane transporter activity [inference]

L-histidine transmembrane transporter activity

salt transmembrane transporter activity [inference]

L-lysine transmembrane transporter activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

lysosomal amino acid transporter 1 homolog

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
V: Defense mechanisms

Displaying 1 entry
InterPro
PQ-loop repeat

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:3211	lysosomal storage disease	Alliance of Genome Resources

Ortholog

Displaying entries **61 - 70** of **110** in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Salmo salar	106572031		SALSA38717
Equus asinus asinus	106839788		EQUAS11166
Marmota marmota marmota	107142184	9994_0:002e2c
Ictalurus punctatus	108265582		ICTPU30237
Rhinopithecus bieti	108515265		RHIBE04700
Cyprinus carpio carpio	109080589		CYPCA73737
Castor canadensis	109687477	51338_0:001bf8
Phascolarctos cinereus	110198714		PHACI30675
Mus caroli	110293597	10089_0:0010ef
Mus pahari	110323580	10093_0:001d7e