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activated leukocyte cell adhesion molecule

Summary

Gene Symbol

ALCAM

Organism

Homo sapiens (human)

External Links

NCBI Gene

214

PubChem

214

Alliance of Genome Resources

HGNC:400

Annotation

Keyword

3D-structure
Adaptive immunity
Alternative splicing
Cell adhesion
Cell membrane
Cell projection
Direct protein sequencing
Disulfide bond
Glycoprotein
Immunoglobulin domain
Reference proteome
Repeat
Secreted
Signal
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q13740	Activated leukocyte cell adhesion molecule
B3KNN9	Activated leukocyte cell adhesion molecule

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
adaptive immune response	IEA
cell adhesion	ISS
cell adhesion	IBA
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	IMP	16352806
signal transduction	TAS	7760007

GO Hierarchy

biological process

immune system process [inference]

immune response [inference]

adaptive immune response

cellular process [inference]

cell adhesion

cell-cell adhesion [inference]

cell-cell adhesion via plasma-membrane adhesion molecules [inference]

heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules

signal transduction

cell growth [inference]

developmental cell growth [inference]

neuron projection extension

axon extension [inference]

axon extension involved in axon guidance

neuron projection extension involved in neuron projection guidance [inference]

axon extension involved in axon guidance

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

neuron projection guidance [inference]

axon guidance [inference]

growth [inference]

cell growth [inference]

developmental cell growth [inference]

neuron projection extension

axon extension [inference]

axon extension involved in axon guidance

neuron projection extension involved in neuron projection guidance [inference]

axon extension involved in axon guidance

developmental growth [inference]

developmental cell growth [inference]

neuron projection extension

axon extension [inference]

axon extension involved in axon guidance

neuron projection extension involved in neuron projection guidance [inference]

axon extension involved in axon guidance

developmental growth involved in morphogenesis [inference]

neuron projection extension

axon extension [inference]

axon extension involved in axon guidance

neuron projection extension involved in neuron projection guidance [inference]

axon extension involved in axon guidance

response to stimulus [inference]

immune response [inference]

adaptive immune response

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
immunological synapse	IDA	15294938
plasma membrane	ISS
plasma membrane	IDA	15294938
plasma membrane	IBA
focal adhesion	HDA	21423176

GO Hierarchy

cellular component

protein-containing complex [inference]

receptor complex [inference]

plasma membrane signaling receptor complex [inference]

T cell receptor complex

membrane protein complex [inference]

plasma membrane protein complex [inference]

plasma membrane signaling receptor complex [inference]

T cell receptor complex

cellular anatomical entity [inference]

immunological synapse

membrane [inference]

plasma membrane

cell junction [inference]

anchoring junction [inference]

cell-substrate junction [inference]

focal adhesion

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

cell body [inference]

neuronal cell body

side of membrane [inference]

external side of plasma membrane

Displaying **all 3** entries
GO Term	Evidence Code	PMID
signaling receptor binding	TAS	7760007
protein binding	IPI	24945728 26146185 33961781
identical protein binding	IPI	26146185

GO Hierarchy

molecular function

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

CD166 antigen

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 5** entries
InterPro
CD80-like, immunoglobulin C2-set
Immunoglobulin subtype
Immunoglobulin-like domain superfamily
Immunoglobulin-like domain
Immunoglobulin-like fold

Ortholog

Displaying entries **1 - 10** of 93 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	214	Xenbase:XB-GENE-491704
Mus musculus	11658	Xenbase:XB-GENE-491704	MOUSE18059
Danio rerio	30194	Xenbase:XB-GENE-491704	DANRE00362
Rattus norvegicus	79559	Xenbase:XB-GENE-491704	RATNO04723
Bos taurus	281614		BOVIN14427
Danio rerio	323919		DANRE08625
Sus scrofa	397269		PIGXX05771
Pan troglodytes	460565		PANTR31759
Canis lupus familiaris	478550		CANLF13261
Macaca mulatta	703777		MACMU28192

GlyTouCan

GlyComb

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UniCarb-DR

LM-GlycoRepo

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External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements