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transcription factor 7 like 2, T cell specific, HMG box
Summary
- Gene Symbol
-
- Tcf7l2
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Activator
- Alternative splicing
- DNA-binding
- Isopeptide bond
- Nucleus
- Phosphoprotein
- Proteomics identification
- Reference proteome
- Repressor
- Transcription regulation
- Ubl conjugation
- Wnt signaling pathway
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| pituitary gland development | ||
| embryonic hindgut morphogenesis | ||
| negative regulation of extrinsic apoptotic signaling pathway |
GO Hierarchy
- regulation of hormone metabolic process
- regulation of myelination
biological process
metabolic process [inference]
cellular process [inference]
developmental process [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of RNA metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of carbohydrate metabolic process [inference]
regulation of lipid metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
regulation of signaling [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of programmed cell death [inference]
regulation of cell differentiation [inference]
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
regulation of cellular localization [inference]
regulation of biological quality [inference]
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| promoter-specific chromatin binding | ||
| protein binding | ||
| transcription cis-regulatory region binding | ||
| RNA polymerase II cis-regulatory region sequence-specific DNA binding | ||
| sequence-specific DNA binding |
GO Hierarchy
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:10283 | prostate cancer | |
| DOID:11714 | gestational diabetes | |
| DOID:1612 | breast cancer | |
| DOID:1793 | pancreatic cancer | |
| DOID:9256 | colorectal cancer | |
| DOID:9351 | diabetes mellitus | |
| DOID:9352 | type 2 diabetes mellitus | |
| DOID:9970 | obesity |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 101095618 | FELCA27475 | ||
| 122202378 | PANLE02997 | ||
| 100153922 | PIGXX08512 | ||
| 540481 | BOVIN21565 | ||
| 102180102 | CAPHI17689 | ||
| 679869 | RGD:1583621 | RATNO16863 | |
| 100021451 | MONDO03526 | ||
| 102459521 | PELSI16203 | ||
| 103657263 | URSMA04178 | ||
| 114035619 | VOMUR03879 |
