Submissions
GlyTouCan
Glycan Structure Repository
GlyComb
Glycoconjugate Repository
GlycoPOST
Glycomics MS raw data Repository
UniCarb-DR
Glycomics MS Repository for glycan annotations from GlycoWorkbench
LM-GlycoRepo
Repository for lectin-assisted multimodality data
All Resources
Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
coagulation factor VIII
Summary
- Gene Symbol
-
- F8
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acute phase
- Alternative splicing
- Calcium
- Direct protein sequencing
- Disease variant
- Disulfide bond
- Glycoprotein
- Hemophilia
- Metal-binding
- Pharmaceutical
- Reference proteome
- Repeat
- Secreted
- Signal
- Sulfation
- Thrombophilia
- Proteins
| UniProt | Protein Name |
|---|---|
| P00451 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| acute-phase response | ||
| blood coagulation, intrinsic pathway | ||
| blood coagulation |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| endoplasmic reticulum-Golgi intermediate compartment membrane | ||
| platelet alpha granule lumen | ||
| Golgi lumen | ||
| COPII-coated ER to Golgi transport vesicle | ||
| endoplasmic reticulum lumen |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| oxidoreductase activity | ||
| copper ion binding |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Laccase
- Functional Category
-
- C: Energy production and conversion
- M: Cell wall/membrane/envelope biogenesis
- Q: Secondary metabolites biosynthesis, transport and catabolism
| Gene Ontology |
|---|
| copper ion binding |
| metal ion binding |
| oxidoreductase activity |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060574 | von Willebrand's disease 2 | |
| DOID:12134 | factor VIII deficiency | |
| DOID:801 | hemarthrosis | |
| DOID:9279 | hyperhomocysteinemia | |
| DOID:9352 | type 2 diabetes mellitus |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 14069 | MGI:88383 | MOUSE65911 | ||
| 302470 | RGD:727845 | RATNO14121 | ||
| 397339 | PIGXX38320 | |||
| 403875 | CANLF20329 | |||
| 445944 | TAKRU10920 | |||
| 473838 | 9598_0:005900 | |||
| 100063026 | HORSE44391 | |||
| 100084142 | ORNAN23127 | |||
| 100174452 | 9601_0:00521f | PONAB37286 | ||
| 100223378 | TAEGU22681 |
