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neuromedin U receptor 2

Summary

Gene Symbol

Nmur2

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

216749

PubChem

216749

Alliance of Genome Resources

MGI:2441765

Annotation

Keyword

Cell membrane
Disulfide bond
G-protein coupled receptor
Glycoprotein
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q8BZ39

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **6 - 8** of 8 in total

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2
GO Term	Evidence Code	PMID
grooming behavior	IMP	17030627
reduction of food intake in response to dietary excess	IMP	17030627
phospholipase C-activating G protein-coupled receptor signaling pathway	IEA ISO

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway [inference]

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic anion transmembrane transport [inference]

chloride transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic anion transmembrane transport [inference]

chloride transmembrane transport

multicellular organismal process [inference]

behavior [inference]

grooming behavior

feeding behavior [inference]

eating behavior [inference]

reduction of food intake in response to dietary excess

multicellular organismal response to stress [inference]

response to pain

response to stimulus [inference]

response to stress [inference]

multicellular organismal response to stress [inference]

response to pain

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic anion transport [inference]

chloride transport [inference]

chloride transmembrane transport

monoatomic anion transmembrane transport [inference]

chloride transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic anion transmembrane transport [inference]

chloride transmembrane transport

inorganic anion transport [inference]

chloride transport [inference]

chloride transmembrane transport

inorganic anion transmembrane transport [inference]

chloride transmembrane transport

secretion [inference]

icosanoid secretion [inference]

arachidonic acid secretion

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic anion transmembrane transport [inference]

chloride transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic anion transmembrane transport [inference]

chloride transmembrane transport

organic substance transport [inference]

lipid transport [inference]

fatty acid transport [inference]

long-chain fatty acid transport [inference]

arachidonate transport [inference]

arachidonic acid secretion

organic anion transport [inference]

carboxylic acid transport [inference]

monocarboxylic acid transport [inference]

fatty acid transport [inference]

long-chain fatty acid transport [inference]

arachidonate transport [inference]

arachidonic acid secretion

icosanoid transport [inference]

icosanoid secretion [inference]

arachidonic acid secretion

arachidonate transport [inference]

arachidonic acid secretion

organic acid transport [inference]

carboxylic acid transport [inference]

monocarboxylic acid transport [inference]

fatty acid transport [inference]

long-chain fatty acid transport [inference]

arachidonate transport [inference]

arachidonic acid secretion

icosanoid transport [inference]

icosanoid secretion [inference]

arachidonic acid secretion

arachidonate transport [inference]

arachidonic acid secretion

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway [inference]

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of nervous system process [inference]

regulation of sensory perception [inference]

regulation of sensory perception of pain

Displaying **all 2** entries
GO Term	Evidence Code	PMID
membrane	IC ISO	15635449
plasma membrane	IBA IEA ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

Displaying **all 5** entries
GO Term	Evidence Code	PMID
neuromedin U receptor activity	IEA ISO
neuropeptide receptor activity	IBA IPI ISO	15635449
intracellular calcium activated chloride channel activity	IEA ISO
neuromedin U binding	IEA ISO
GTP binding	IEA ISO

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic ion channel activity [inference]

monoatomic anion channel activity [inference]

chloride channel activity [inference]

intracellular chloride channel activity [inference]

intracellular calcium activated chloride channel activity

monoatomic anion transmembrane transporter activity [inference]

monoatomic anion channel activity [inference]

chloride channel activity [inference]

intracellular chloride channel activity [inference]

intracellular calcium activated chloride channel activity

chloride transmembrane transporter activity [inference]

chloride channel activity [inference]

intracellular chloride channel activity [inference]

intracellular calcium activated chloride channel activity

inorganic molecular entity transmembrane transporter activity [inference]

inorganic anion transmembrane transporter activity [inference]

chloride transmembrane transporter activity [inference]

chloride channel activity [inference]

intracellular chloride channel activity [inference]

intracellular calcium activated chloride channel activity

passive transmembrane transporter activity [inference]

channel activity [inference]

monoatomic ion channel activity [inference]

monoatomic anion channel activity [inference]

chloride channel activity [inference]

intracellular chloride channel activity [inference]

intracellular calcium activated chloride channel activity

salt transmembrane transporter activity [inference]

chloride transmembrane transporter activity [inference]

chloride channel activity [inference]

intracellular chloride channel activity [inference]

intracellular calcium activated chloride channel activity

binding [inference]

amide binding [inference]

peptide binding [inference]

neuropeptide binding [inference]

neuromedin U binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

GTP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleoside triphosphate binding [inference]

GTP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

molecular transducer activity [inference]

signaling receptor activity [inference]

peptide receptor activity [inference]

G protein-coupled peptide receptor activity [inference]

neuropeptide receptor activity

neuromedin U receptor activity

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity [inference]

G protein-coupled peptide receptor activity [inference]

neuropeptide receptor activity

neuromedin U receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

Neuromedin U receptor

Functional Category

E: Amino acid transport and metabolism
K: Transcription
L: Replication, recombination and repair
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 3** entries
Gene Ontology
neuromedin U receptor activity
neuropeptide receptor activity
neuropeptide signaling pathway

Displaying **all 5** entries
InterPro
G protein-coupled receptor, rhodopsin-like
GPCR, rhodopsin-like, 7TM
Neuromedin U receptor, type 2
Neuromedin U receptor
Neuromedin-U receptor 2, C-terminal domain

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:9970	obesity	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of **108** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	40393		FB:FBgn0037100
Drosophila melanogaster	41638		FB:FBgn0038139
Drosophila melanogaster	41639		FB:FBgn0038140
Drosophila melanogaster	41713		FB:FBgn0038201
Homo sapiens	56923		HGNC:16454	HUMAN81901
Rattus norvegicus	64042	10116_1:003a1f	RGD:621155	RATNO00175
Caenorhabditis elegans	173398		WB:WBGene00019616
Pan troglodytes	471713			PANTR36643
Canis lupus familiaris	489170			CANLF14894
Bos taurus	507439			BOVIN33797