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thrombomodulin
Summary
- Gene Symbol
-
- Thbd
- Organism
- Mus musculus (house mouse)
Annotation
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| negative regulation of coagulation | ||
| negative regulation of blood coagulation | ||
| response to X-ray | ||
| response to cAMP | ||
| response to lipopolysaccharide |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| external side of plasma membrane | ||
| apicolateral plasma membrane | ||
| plasma membrane | ||
| cell surface | ||
| serine-type endopeptidase complex |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| calcium ion binding | ||
| transmembrane signaling receptor activity |
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- C-type lectin-like
- Functional Category
-
- G: Carbohydrate transport and metabolism
- I: Lipid transport and metabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| blood coagulation |
| calcium ion binding |
| hemostasis |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050156 | idiopathic pulmonary fibrosis | |
| DOID:0080301 | atypical hemolytic-uremic syndrome | |
| DOID:0111908 | thrombophilia due to thrombomodulin defect | |
| DOID:0112313 | brain small vessel disease | |
| DOID:10223 | dermatomyositis | |
| DOID:10652 | Alzheimer's disease | |
| DOID:10763 | hypertension | |
| DOID:11247 | disseminated intravascular coagulation | |
| DOID:11394 | adult respiratory distress syndrome | |
| DOID:12132 | granulomatosis with polyangiitis |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 7056 | HGNC:11784 | HUMAN56301 | ||
| 42820 | FB:FBgn0085384 | |||
| 47137 | FB:FBgn0001321 | |||
| 83580 | 10116_1:001673 | RGD:621299 | RATNO26151 | |
| 180836 | WB:WBGene00020921 | |||
| 469898 | PANTR24490 | |||
| 474355 | CANLF09242 | |||
| 702132 | MACMU01602 | |||
| 100049012 | FELCA08106 | |||
| 100078930 | ORNAN11578 |
