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PX domain containing serine/threonine kinase

Summary

Gene Symbol

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

218699

PubChem

218699

Alliance of Genome Resources

MGI:1289230

Annotation

Keyword

Actin-binding
Alternative splicing
Cell membrane
Cytoplasm
Proteomics identification
Reference proteome

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q8BX57	Modulator of Na,K-ATPase
A0A2C9F2B5	Modulator of Na,K-ATPase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
protein phosphorylation
inflammatory response	ISO
inflammatory response	IEA
negative regulation of ATP-dependent activity	IDA	16135750
negative regulation of monoatomic ion transport	IDA	16135750

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

macromolecule modification [inference]

protein modification process [inference]

protein phosphorylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

cellular process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission

regulation of localization [inference]

regulation of transport [inference]

regulation of monoatomic ion transport [inference]

negative regulation of monoatomic ion transport

negative regulation of transport [inference]

negative regulation of monoatomic ion transport

negative regulation of biological process [inference]

negative regulation of transport [inference]

negative regulation of monoatomic ion transport

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission

regulation of molecular function [inference]

regulation of ATP-dependent activity [inference]

negative regulation of ATP-dependent activity

negative regulation of molecular function [inference]

negative regulation of ATP-dependent activity

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
nucleus	ISO
cytoplasm	ISS
cytoplasm	ISO
cytoplasm	IDA	16135750
cytoplasm	IBA

GO Hierarchy

cellular component

protein-containing complex

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

centriolar satellite

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying **all 5** entries
GO Term	Evidence Code	PMID
actin binding	IEA
protein kinase activity	IEA
protein binding	IPI	16135750
ATP binding	IEA
phosphatidylinositol binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

protein kinase activity

phosphotransferase activity, alcohol group as acceptor [inference]

protein kinase activity

catalytic activity, acting on a protein [inference]

protein kinase activity

binding [inference]

protein binding

cytoskeletal protein binding [inference]

actin binding

lipid binding [inference]

phospholipid binding [inference]

phosphatidylinositol binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

PX domain-containing protein kinase-like protein

Functional Category

M: Cell wall/membrane/envelope biogenesis
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
ATP binding
negative regulation of monoatomic ion transport
phosphatidylinositol binding

Displaying **all 4** entries
InterPro
PX domain superfamily
Phox homology
Protein kinase domain
Protein kinase-like domain superfamily

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements