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transketolase

Summary

Gene Symbol

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

21881

PubChem

21881

Alliance of Genome Resources

MGI:105992

Annotation

Keyword

Acetylation
Calcium
Direct protein sequencing
Isopeptide bond
Magnesium
Metal-binding
Phosphoprotein
Reference proteome
Thiamine pyrophosphate
Transferase
Ubl conjugation

Proteins

Displaying 1 entry
UniProt	Protein Name
P40142	P68

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
glyceraldehyde-3-phosphate biosynthetic process	IEA ISO
regulation of growth	IMP	12167708
pentose-phosphate shunt	IDA ISO	13405914 5360673
xylulose 5-phosphate biosynthetic process	IDA	5360673
pentose-phosphate shunt, non-oxidative branch	IBA IMP ISO	32295803

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt

organonitrogen compound metabolic process [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt

biosynthetic process [inference]

cellular biosynthetic process [inference]

aldehyde biosynthetic process [inference]

glyceraldehyde-3-phosphate biosynthetic process

organic substance biosynthetic process [inference]

aldehyde biosynthetic process [inference]

glyceraldehyde-3-phosphate biosynthetic process

organophosphate biosynthetic process [inference]

carbohydrate derivative biosynthetic process [inference]

cellular metabolic process [inference]

cellular aldehyde metabolic process [inference]

glyceraldehyde-3-phosphate metabolic process [inference]

aldehyde biosynthetic process [inference]

glyceraldehyde-3-phosphate biosynthetic process

generation of precursor metabolites and energy [inference]

NADPH regeneration [inference]

pentose-phosphate shunt

pentose-phosphate shunt, non-oxidative branch

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt

glyceraldehyde-3-phosphate metabolic process [inference]

ribose phosphate metabolic process [inference]

pentose-phosphate shunt, non-oxidative branch

glucose 6-phosphate metabolic process [inference]

pentose-phosphate shunt

xylulose 5-phosphate metabolic process [inference]

xylulose 5-phosphate biosynthetic process

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt

glyceraldehyde-3-phosphate metabolic process [inference]

ribose phosphate metabolic process [inference]

pentose-phosphate shunt, non-oxidative branch

glucose 6-phosphate metabolic process [inference]

pentose-phosphate shunt

xylulose 5-phosphate metabolic process [inference]

xylulose 5-phosphate biosynthetic process

organophosphate biosynthetic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt

cellular biosynthetic process [inference]

aldehyde biosynthetic process [inference]

glyceraldehyde-3-phosphate biosynthetic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt

small molecule metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt

organic substance metabolic process [inference]

cellular aldehyde metabolic process [inference]

glyceraldehyde-3-phosphate metabolic process [inference]

aldehyde biosynthetic process [inference]

glyceraldehyde-3-phosphate biosynthetic process

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt

glyceraldehyde-3-phosphate metabolic process [inference]

ribose phosphate metabolic process [inference]

pentose-phosphate shunt, non-oxidative branch

glucose 6-phosphate metabolic process [inference]

pentose-phosphate shunt

xylulose 5-phosphate metabolic process [inference]

xylulose 5-phosphate biosynthetic process

organophosphate biosynthetic process [inference]

carbohydrate derivative metabolic process [inference]

glyceraldehyde-3-phosphate metabolic process [inference]

ribose phosphate metabolic process [inference]

pentose-phosphate shunt, non-oxidative branch

glucose 6-phosphate metabolic process [inference]

pentose-phosphate shunt

xylulose 5-phosphate metabolic process [inference]

xylulose 5-phosphate biosynthetic process

carbohydrate derivative biosynthetic process [inference]

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt

organonitrogen compound metabolic process [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt

organic substance biosynthetic process [inference]

aldehyde biosynthetic process [inference]

glyceraldehyde-3-phosphate biosynthetic process

organophosphate biosynthetic process [inference]

carbohydrate derivative biosynthetic process [inference]

cellular process [inference]

cellular metabolic process [inference]

cellular aldehyde metabolic process [inference]

glyceraldehyde-3-phosphate metabolic process [inference]

aldehyde biosynthetic process [inference]

glyceraldehyde-3-phosphate biosynthetic process

generation of precursor metabolites and energy [inference]

NADPH regeneration [inference]

pentose-phosphate shunt

pentose-phosphate shunt, non-oxidative branch

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt

glyceraldehyde-3-phosphate metabolic process [inference]

ribose phosphate metabolic process [inference]

pentose-phosphate shunt, non-oxidative branch

glucose 6-phosphate metabolic process [inference]

pentose-phosphate shunt

xylulose 5-phosphate metabolic process [inference]

xylulose 5-phosphate biosynthetic process

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt

glyceraldehyde-3-phosphate metabolic process [inference]

ribose phosphate metabolic process [inference]

pentose-phosphate shunt, non-oxidative branch

glucose 6-phosphate metabolic process [inference]

pentose-phosphate shunt

xylulose 5-phosphate metabolic process [inference]

xylulose 5-phosphate biosynthetic process

organophosphate biosynthetic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt

cellular biosynthetic process [inference]

aldehyde biosynthetic process [inference]

glyceraldehyde-3-phosphate biosynthetic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH regeneration [inference]

pentose-phosphate shunt

biological regulation [inference]

regulation of biological process [inference]

regulation of growth

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
peroxisome	ISO
endoplasmic reticulum membrane	IBA ISO
nucleoplasm	ISO
nuclear body	IEA ISO
myelin sheath	HDA	17634366

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

microbody [inference]

peroxisome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

microbody [inference]

peroxisome

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
monosaccharide binding	ISO
transketolase activity	IBA IDA ISO	12167708 5360673
magnesium ion binding	IEA ISO
calcium ion binding	IEA ISO
protein homodimerization activity	IEA ISO

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transketolase or transaldolase activity [inference]

transketolase activity

binding [inference]

protein binding [inference]

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

carbohydrate binding

monosaccharide binding

small molecule binding [inference]

vitamin binding [inference]

thiamine pyrophosphate binding

monosaccharide binding

quaternary ammonium group binding [inference]

thiamine pyrophosphate binding

heterocyclic compound binding [inference]

thiamine pyrophosphate binding

ion binding [inference]

anion binding [inference]

thiamine pyrophosphate binding

cation binding [inference]

thiamine pyrophosphate binding

metal ion binding [inference]

organic cyclic compound binding [inference]

thiamine pyrophosphate binding

sulfur compound binding [inference]

thiamine pyrophosphate binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

transketolase

Functional Category

C: Energy production and conversion
G: Carbohydrate transport and metabolism
L: Replication, recombination and repair

Displaying **all 6** entries
Gene Ontology
catalytic activity
metal ion binding
pentose-phosphate shunt, non-oxidative branch
thiamine pyrophosphate binding
transferase activity
transketolase activity

Displaying **all 7** entries
InterPro
Thiamin diphosphate-binding fold
Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II
Transketolase binding site
Transketolase conserved site
Transketolase, C-terminal domain
Transketolase, N-terminal
Transketolase-like, pyrimidine-binding domain

Ortholog

Displaying entries **1 - 10** of **130** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	7086		HGNC:11834	HUMAN70575
Drosophila melanogaster	40012		FB:FBgn0036784
Drosophila melanogaster	41027		FB:FBgn0037607
Rattus norvegicus	64524	10116_1:0049ab	RGD:621036	RATNO11733
Caenorhabditis elegans	177906		WB:WBGene00008506
Danio rerio	378713		ZFIN:ZDB-GENE-030909-13
Bos taurus	445425			BOVIN17672
Pan troglodytes	460443			PANTR31353
Canis lupus familiaris	476588			CANLF07416
Xenopus tropicalis	548583		Xenbase:XB-GENE-948072

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements