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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
fructose-bisphosphatase 1
Summary
- Gene Symbol
-
- FBP1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Allosteric enzyme
- Carbohydrate metabolism
- Direct protein sequencing
- Disease variant
- Gluconeogenesis
- Hydrolase
- Magnesium
- Metal-binding
- Nucleotide-binding
- Phosphoprotein
- Reference proteome
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| negative regulation of glycolytic process | ||
| dephosphorylation | ||
| cellular response to magnesium ion | ||
| regulation of gluconeogenesis | ||
| fructose 6-phosphate metabolic process |
GO Hierarchy
biological process
metabolic process [inference]
cellular process [inference]
response to stimulus [inference]
response to stress [inference]
response to abiotic stimulus [inference]
response to chemical [inference]
cellular response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
negative regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of phosphorus metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of small molecule metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of signaling [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of phosphorus metabolic process [inference]
negative regulation of cellular process [inference]
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| RNA polymerase II-specific DNA-binding transcription factor binding | ||
| AMP binding | ||
| monosaccharide binding | ||
| metal ion binding | ||
| protein binding |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
KEGG BRITE Database
Rhea
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:4450 | renal cell carcinoma | |
| DOID:4451 | renal carcinoma | |
| DOID:4464 | collecting duct carcinoma | |
| DOID:4465 | papillary renal cell carcinoma | |
| DOID:4467 | clear cell renal cell carcinoma | |
| DOID:4471 | chromophobe renal cell carcinoma | |
| DOID:4473 | sarcomatoid renal cell carcinoma | |
| DOID:4766 | embryoma | |
| DOID:4896 | bile duct adenocarcinoma | |
| DOID:4897 | bile duct carcinoma |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0000007 | Autosomal recessive inheritance |
| HP:0000737 | Irritability |
| HP:0000980 | Pallor |
| HP:0001249 | Intellectual disability |
| HP:0001250 | Seizure |
| HP:0001252 | Hypotonia |
| HP:0001254 | Lethargy |
| HP:0001259 | Coma |
| HP:0001262 | Excessive daytime somnolence |
| HP:0001397 | Hepatic steatosis |
| Disease ID | Disease Name |
|---|---|
| ORPHA:348 |
|
| OMIM:229700 |
|
PubChem Disease
- MedGen Diseases
- OMIM Phenotypes
- KEGG Diseases
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 105536605 | MANLE22973 | ||
| 101138625 | GORGO41634 | ||
| 100995941 | PANPA39878 | ||
| 465260 | PANTR44371 | ||
| 100456152 | PONAB36348 | ||
| 476299 | CANLF00377 | ||
| 112908705 | VULVU34529 | ||
| 100475720 | AILME11676 | ||
| 101677302 | MUSPF02724 | ||
| 101084832 | FELCA29862 |
