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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
fructose-bisphosphatase 1
Summary
- Gene Symbol
-
- FBP1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Allosteric enzyme
- Carbohydrate metabolism
- Direct protein sequencing
- Disease variant
- Gluconeogenesis
- Hydrolase
- Magnesium
- Metal-binding
- Nucleotide-binding
- Phosphoprotein
- Reference proteome
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| cellular response to insulin stimulus | ||
| cellular response to xenobiotic stimulus | ||
| negative regulation of transcription by RNA polymerase II | ||
| cellular hyperosmotic salinity response | ||
| gluconeogenesis |
GO Hierarchy
biological process
metabolic process [inference]
cellular process [inference]
response to stimulus [inference]
response to stress [inference]
response to abiotic stimulus [inference]
response to chemical [inference]
cellular response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
negative regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of phosphorus metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of small molecule metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of signaling [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of phosphorus metabolic process [inference]
negative regulation of cellular process [inference]
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| RNA polymerase II-specific DNA-binding transcription factor binding | ||
| AMP binding | ||
| monosaccharide binding | ||
| metal ion binding | ||
| protein binding |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
KEGG BRITE Database
Rhea
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050387 | nonpapillary renal cell carcinoma | |
| DOID:0050524 | maturity-onset diabetes of the young | |
| DOID:0050646 | distal arthrogryposis | |
| DOID:0050745 | diffuse large B-cell lymphoma | |
| DOID:0050819 | obsolete Matthew-Wood syndrome | |
| DOID:0050865 | tongue squamous cell carcinoma | |
| DOID:0050873 | follicular lymphoma | |
| DOID:0060891 | Parkinson's disease 19A | |
| DOID:0060895 | Parkinson's disease 4 | |
| DOID:0060896 | Parkinson's disease 23 |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0003265 | Neonatal hyperbilirubinemia |
| HP:0003348 | Hyperalaninemia |
| HP:0003623 | Neonatal onset |
| HP:0004372 | Reduced consciousness |
| HP:0004879 | Intermittent hyperventilation |
| HP:0004913 | Intermittent lactic acidemia |
| HP:0005949 | Apneic episodes in infancy |
| HP:0006582 | Reye syndrome-like episodes |
| HP:0012379 | Abnormal circulating enzyme concentration or activity |
| Disease ID | Disease Name |
|---|---|
| ORPHA:348 |
|
| OMIM:229700 |
|
PubChem Disease
- MedGen Diseases
- OMIM Phenotypes
- KEGG Diseases
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 266822 | WB:WBGene00001404 | ||
| 35265 | FB:FBgn0032820 | ||
| 103188178 | CALMI38478 | ||
| 102359859 | LATCH13894 | ||
| 282672 | ZFIN:ZDB-GENE-021206-11 | DANRE36953 | |
| 335231 | ZFIN:ZDB-GENE-030131-7171 | DANRE36255 | |
| 103029226 | ASTMX11344 | ||
| 103033769 | ASTMX11269 | ||
| 100528384 | ICTPU17236 | ||
| 113576050 | ELEEL16890 |
