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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
fructose-bisphosphatase 1
Summary
- Gene Symbol
-
- FBP1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Allosteric enzyme
- Carbohydrate metabolism
- Direct protein sequencing
- Disease variant
- Gluconeogenesis
- Hydrolase
- Magnesium
- Metal-binding
- Nucleotide-binding
- Phosphoprotein
- Reference proteome
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| cellular response to phorbol 13-acetate 12-myristate | ||
| fructose metabolic process | ||
| cellular hypotonic salinity response | ||
| sucrose biosynthetic process | ||
| cellular response to cAMP |
GO Hierarchy
biological process
metabolic process [inference]
cellular process [inference]
response to stimulus [inference]
response to stress [inference]
response to abiotic stimulus [inference]
response to chemical [inference]
cellular response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
negative regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of phosphorus metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of small molecule metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of signaling [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of phosphorus metabolic process [inference]
negative regulation of cellular process [inference]
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| RNA polymerase II-specific DNA-binding transcription factor binding | ||
| AMP binding | ||
| monosaccharide binding | ||
| metal ion binding | ||
| protein binding |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
KEGG BRITE Database
Rhea
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080199 | colorectal carcinoma | |
| DOID:0111040 | glycogen storage disease IXd | |
| DOID:0111041 | glycogen storage disease IXb | |
| DOID:0111042 | glycogen storage disease IXa | |
| DOID:0111043 | glycogen storage disease IXc | |
| DOID:10283 | prostate cancer | |
| DOID:10286 | prostate carcinoma | |
| DOID:10534 | stomach cancer | |
| DOID:1059 | intellectual disability | |
| DOID:10629 | microphthalmia |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0001649 | Tachycardia |
| HP:0001942 | Metabolic acidosis |
| HP:0001943 | Hypoglycemia |
| HP:0001945 | Fever |
| HP:0001946 | Ketosis |
| HP:0001998 | Neonatal hypoglycemia |
| HP:0002013 | Vomiting |
| HP:0002014 | Diarrhea |
| HP:0002094 | Dyspnea |
| HP:0002098 | Respiratory distress |
| Disease ID | Disease Name |
|---|---|
| ORPHA:348 |
|
| OMIM:229700 |
|
PubChem Disease
- MedGen Diseases
- OMIM Phenotypes
- KEGG Diseases
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 113589699 | ELEEL01682 | ||
| 106561989 | SALSA67735 | ||
| 115149348 | SALTR20739 | ||
| 115200684 | SALTR21714 | ||
| 101156992 | ORYLA02406 | ||
| 100705870 | ORENI66147 | ||
| 115593207 | SPAAU33261 | ||
| 380220 | Xenbase:XB-GENE-1002601 | ||
| 779029 | Xenbase:XB-GENE-17330404 | ||
| 394750 | Xenbase:XB-GENE-1002596 |
