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transient receptor potential cation channel, subfamily C, member 3

Summary

Gene Symbol

Trpc3

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

22065

PubChem

22065

Alliance of Genome Resources

MGI:109526

Annotation

Keyword

ANK repeat
Calcium channel
Cell membrane
Glycoprotein
Metal-binding
Reference proteome
Repeat
Transmembrane helix

Proteins

Displaying **all 3** entries
UniProt	Protein Name
Q8BNT8
Q8CCQ1
Q9QZC1	Receptor-activated cation channel TRP3 Transient receptor protein 3 Trp-related protein 3

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
single fertilization	IBA
positive regulation of calcium ion transport into cytosol	ISO
positive regulation of calcium ion transport into cytosol	IEA
response to ATP	ISO
response to ATP	IEA

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

calcium ion transmembrane transport

reproductive process [inference]

fertilization [inference]

single fertilization

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis [inference]

regulation of cytosolic calcium ion concentration

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis [inference]

regulation of cytosolic calcium ion concentration

monoatomic cation homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis [inference]

regulation of cytosolic calcium ion concentration

calcium ion homeostasis [inference]

intracellular calcium ion homeostasis [inference]

regulation of cytosolic calcium ion concentration

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis [inference]

regulation of cytosolic calcium ion concentration

inorganic ion homeostasis [inference]

calcium ion homeostasis [inference]

intracellular calcium ion homeostasis [inference]

regulation of cytosolic calcium ion concentration

response to stimulus [inference]

response to chemical [inference]

response to organic substance [inference]

response to organonitrogen compound [inference]

response to purine-containing compound [inference]

response to ATP

response to organic cyclic compound [inference]

response to purine-containing compound [inference]

response to ATP

response to organophosphorus [inference]

response to ATP

response to calcium ion

response to inorganic substance [inference]

response to metal ion [inference]

response to calcium ion

response to nitrogen compound [inference]

response to organonitrogen compound [inference]

response to purine-containing compound [inference]

response to ATP

response to oxygen-containing compound [inference]

response to salt [inference]

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

calcium ion transport [inference]

calcium ion transmembrane transport

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

calcium ion transmembrane transport

organic substance transport [inference]

calcium ion transport [inference]

calcium ion transmembrane transport

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of transmembrane transport [inference]

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of calcium ion transport into cytosol

regulation of monoatomic ion transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of calcium ion transport into cytosol

regulation of monoatomic cation transmembrane transport [inference]

regulation of calcium ion transmembrane transport [inference]

regulation of calcium ion transport into cytosol [inference]

positive regulation of calcium ion transport into cytosol

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of calcium ion transport into cytosol

positive regulation of cation transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of calcium ion transport into cytosol

regulation of monoatomic ion transport [inference]

regulation of metal ion transport [inference]

regulation of calcium ion transport [inference]

positive regulation of calcium ion transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of calcium ion transport into cytosol

regulation of calcium ion transmembrane transport [inference]

regulation of calcium ion transport into cytosol [inference]

positive regulation of calcium ion transport into cytosol

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of calcium ion transport into cytosol

regulation of monoatomic ion transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of calcium ion transport into cytosol

regulation of monoatomic cation transmembrane transport [inference]

regulation of calcium ion transmembrane transport [inference]

regulation of calcium ion transport into cytosol [inference]

positive regulation of calcium ion transport into cytosol

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of calcium ion transport into cytosol

positive regulation of cation transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of calcium ion transport into cytosol

positive regulation of monoatomic ion transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of calcium ion transport into cytosol

positive regulation of calcium ion transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of calcium ion transport into cytosol

positive regulation of transport [inference]

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of calcium ion transport into cytosol

positive regulation of monoatomic ion transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of calcium ion transport into cytosol

positive regulation of calcium ion transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of calcium ion transport into cytosol

regulation of cellular localization [inference]

regulation of calcium ion transport into cytosol [inference]

positive regulation of calcium ion transport into cytosol

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of calcium ion transport into cytosol

positive regulation of response to stimulus [inference]

positive regulation of muscle adaptation [inference]

positive regulation of cardiac muscle adaptation [inference]

positive regulation of cardiac muscle hypertrophy in response to stress

positive regulation of transport [inference]

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of calcium ion transport into cytosol

positive regulation of monoatomic ion transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of calcium ion transport into cytosol

positive regulation of calcium ion transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of calcium ion transport into cytosol

positive regulation of multicellular organismal process [inference]

positive regulation of muscle hypertrophy [inference]

positive regulation of cardiac muscle hypertrophy [inference]

positive regulation of cardiac muscle hypertrophy in response to stress

positive regulation of muscle adaptation [inference]

positive regulation of cardiac muscle adaptation [inference]

positive regulation of cardiac muscle hypertrophy in response to stress

regulation of response to stimulus [inference]

regulation of muscle adaptation [inference]

regulation of cardiac muscle hypertrophy [inference]

positive regulation of cardiac muscle hypertrophy [inference]

positive regulation of cardiac muscle hypertrophy in response to stress

regulation of cardiac muscle hypertrophy in response to stress [inference]

positive regulation of cardiac muscle hypertrophy in response to stress

regulation of cardiac muscle adaptation [inference]

positive regulation of cardiac muscle adaptation [inference]

positive regulation of cardiac muscle hypertrophy in response to stress

regulation of cardiac muscle hypertrophy in response to stress [inference]

positive regulation of cardiac muscle hypertrophy in response to stress

positive regulation of muscle adaptation [inference]

positive regulation of cardiac muscle adaptation [inference]

positive regulation of cardiac muscle hypertrophy in response to stress

positive regulation of response to stimulus [inference]

positive regulation of muscle adaptation [inference]

positive regulation of cardiac muscle adaptation [inference]

positive regulation of cardiac muscle hypertrophy in response to stress

regulation of response to stress [inference]

regulation of cardiac muscle hypertrophy in response to stress [inference]

positive regulation of cardiac muscle hypertrophy in response to stress

regulation of cellular process [inference]

regulation of transmembrane transport [inference]

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of calcium ion transport into cytosol

regulation of monoatomic ion transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of calcium ion transport into cytosol

regulation of monoatomic cation transmembrane transport [inference]

regulation of calcium ion transmembrane transport [inference]

regulation of calcium ion transport into cytosol [inference]

positive regulation of calcium ion transport into cytosol

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of calcium ion transport into cytosol

positive regulation of cation transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of calcium ion transport into cytosol

positive regulation of cellular process [inference]

positive regulation of transmembrane transport [inference]

positive regulation of monoatomic ion transmembrane transport [inference]

positive regulation of cation transmembrane transport [inference]

positive regulation of calcium ion transmembrane transport [inference]

positive regulation of calcium ion transport into cytosol

regulation of cellular localization [inference]

regulation of calcium ion transport into cytosol [inference]

positive regulation of calcium ion transport into cytosol

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of muscle system process [inference]

regulation of muscle hypertrophy [inference]

regulation of cardiac muscle hypertrophy [inference]

positive regulation of cardiac muscle hypertrophy [inference]

positive regulation of cardiac muscle hypertrophy in response to stress

regulation of cardiac muscle hypertrophy in response to stress [inference]

positive regulation of cardiac muscle hypertrophy in response to stress

positive regulation of muscle hypertrophy [inference]

positive regulation of cardiac muscle hypertrophy [inference]

positive regulation of cardiac muscle hypertrophy in response to stress

regulation of muscle adaptation [inference]

regulation of cardiac muscle hypertrophy [inference]

positive regulation of cardiac muscle hypertrophy [inference]

positive regulation of cardiac muscle hypertrophy in response to stress

regulation of cardiac muscle hypertrophy in response to stress [inference]

positive regulation of cardiac muscle hypertrophy in response to stress

regulation of cardiac muscle adaptation [inference]

positive regulation of cardiac muscle adaptation [inference]

positive regulation of cardiac muscle hypertrophy in response to stress

regulation of cardiac muscle hypertrophy in response to stress [inference]

positive regulation of cardiac muscle hypertrophy in response to stress

positive regulation of muscle adaptation [inference]

positive regulation of cardiac muscle adaptation [inference]

positive regulation of cardiac muscle hypertrophy in response to stress

positive regulation of multicellular organismal process [inference]

positive regulation of muscle hypertrophy [inference]

positive regulation of cardiac muscle hypertrophy [inference]

positive regulation of cardiac muscle hypertrophy in response to stress

positive regulation of muscle adaptation [inference]

positive regulation of cardiac muscle adaptation [inference]

positive regulation of cardiac muscle hypertrophy in response to stress

regulation of biological quality [inference]

positive regulation of cytosolic calcium ion concentration [inference]

positive regulation of calcium ion transport into cytosol

regulation of calcium ion transport into cytosol [inference]

positive regulation of calcium ion transport into cytosol

Displaying **all 3** entries
GO Term	Evidence Code	PMID
plasma membrane	TAS
plasma membrane	IBA
cation channel complex	IBA

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

cation channel complex

transporter complex [inference]

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

cation channel complex

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
calcium-activated cation channel activity	ISO
calcium-activated cation channel activity	IEA
calcium channel activity
protein binding	IPI	19812035
store-operated calcium channel activity	ISS

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic ion channel activity [inference]

monoatomic cation channel activity [inference]

calcium channel activity

store-operated calcium channel activity

ligand-gated monoatomic cation channel activity [inference]

calcium-activated cation channel activity

ligand-gated monoatomic ion channel activity [inference]

ligand-gated monoatomic cation channel activity [inference]

calcium-activated cation channel activity

monoatomic cation transmembrane transporter activity [inference]

monoatomic cation channel activity [inference]

calcium channel activity

store-operated calcium channel activity

ligand-gated monoatomic cation channel activity [inference]

calcium-activated cation channel activity

metal ion transmembrane transporter activity [inference]

calcium ion transmembrane transporter activity [inference]

calcium channel activity

store-operated calcium channel activity

inorganic molecular entity transmembrane transporter activity [inference]

inorganic cation transmembrane transporter activity [inference]

metal ion transmembrane transporter activity [inference]

calcium ion transmembrane transporter activity [inference]

calcium channel activity

store-operated calcium channel activity

passive transmembrane transporter activity [inference]

channel activity [inference]

monoatomic ion channel activity [inference]

monoatomic cation channel activity [inference]

calcium channel activity

store-operated calcium channel activity

ligand-gated monoatomic cation channel activity [inference]

calcium-activated cation channel activity

ligand-gated monoatomic ion channel activity [inference]

ligand-gated monoatomic cation channel activity [inference]

calcium-activated cation channel activity

gated channel activity [inference]

ligand-gated channel activity [inference]

ligand-gated monoatomic ion channel activity [inference]

ligand-gated monoatomic cation channel activity [inference]

calcium-activated cation channel activity

monoatomic ion-gated channel activity [inference]

calcium-activated cation channel activity

salt transmembrane transporter activity [inference]

calcium ion transmembrane transporter activity [inference]

calcium channel activity

store-operated calcium channel activity

binding [inference]

protein binding

small molecule binding [inference]

alcohol binding [inference]

inositol 1,4,5 trisphosphate binding

ion binding [inference]

anion binding [inference]

inositol 1,4,5 trisphosphate binding

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Short transient receptor potential channel

Functional Category

E: Amino acid transport and metabolism
J: Translation, ribosomal structure and biogenesis
T: Signal transduction mechanisms

Displaying **all 7** entries
Gene Ontology
calcium channel activity
calcium ion transmembrane transport
inositol 1,4,5 trisphosphate binding
monoatomic ion channel activity
monoatomic ion transport
regulation of cytosolic calcium ion concentration
store-operated calcium channel activity

Displaying **all 5** entries
InterPro
Ankyrin repeat-containing domain superfamily
Ankyrin repeat
Ion transport domain
Transient receptor ion channel domain
Transient receptor potential channel, canonical

Ortholog

Displaying entry **81 - 81** of 81 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Ursus americanus	123793117		URSAM20617

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements