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MIRAGE
lysine (K)-specific demethylase 6A
Summary
- Gene Symbol
-
- Kdm6a
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Alternative splicing
- Chromatin regulator
- Dioxygenase
- Iron
- Metal-binding
- Methylation
- Nucleus
- Oxidoreductase
- Phosphoprotein
- Reference proteome
- Repeat
- TPR repeat
- Zinc
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway | ||
| cellular response to transforming growth factor beta stimulus | ||
| multicellular organism growth | ||
| cellular response to vitamin D | ||
| neural tube closure |
GO Hierarchy
biological process
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of signaling [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
regulation of programmed cell death [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| nucleus | ||
| MLL3/4 complex | ||
| nucleoplasm | ||
| histone methyltransferase complex |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| metal ion binding | ||
| histone H3K27me2/H3K27me3 demethylase activity | ||
| RNA polymerase II cis-regulatory region sequence-specific DNA binding | ||
| protein binding | ||
| identical protein binding |
GO Hierarchy
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060081 | triple-receptor negative breast cancer | |
| DOID:0060473 | Kabuki syndrome | |
| DOID:0080188 | chronic myelomonocytic leukemia | |
| DOID:0080202 | adenoid cystic carcinoma | |
| DOID:10283 | prostate cancer | |
| DOID:10534 | stomach cancer | |
| DOID:1574 | alcohol use disorder | |
| DOID:1612 | breast cancer | |
| DOID:1996 | rectum adenocarcinoma | |
| DOID:234 | colon adenocarcinoma |
