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aldehyde dehydrogenase 9 family member A1

Summary

Gene Symbol

ALDH9A1

Aliases

Organism

Homo sapiens (human)

External Links

NCBI Gene

223

HGNC

412

KEGG Gene ID

hsa:223

PubChem

223

Alliance of Genome Resources

HGNC:412

Annotation

Keyword

3D-structure
Acetylation
Alternative initiation
Alternative splicing
Cytoplasm
Direct protein sequencing
NAD
Oxidoreductase
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
P49189	Aldehyde dehydrogenase E3 isozyme Aldehyde dehydrogenase family 9 member A1 Formaldehyde dehydrogenase Gamma-aminobutyraldehyde dehydrogenase R-aminobutyraldehyde dehydrogenase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
cellular aldehyde metabolic process	IDA	30914451 8645224
carnitine biosynthetic process	IEA TAS
protein homotetramerization	IDA	30914451

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

amino-acid betaine metabolic process [inference]

amino-acid betaine biosynthetic process [inference]

carnitine biosynthetic process

carnitine metabolic process [inference]

carnitine biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

amino-acid betaine biosynthetic process [inference]

carnitine biosynthetic process

organonitrogen compound metabolic process [inference]

cellular modified amino acid metabolic process [inference]

amino-acid betaine metabolic process [inference]

amino-acid betaine biosynthetic process [inference]

carnitine biosynthetic process

carnitine metabolic process [inference]

carnitine biosynthetic process

cellular modified amino acid biosynthetic process [inference]

amino-acid betaine biosynthetic process [inference]

carnitine biosynthetic process

organonitrogen compound biosynthetic process [inference]

cellular modified amino acid biosynthetic process [inference]

amino-acid betaine biosynthetic process [inference]

carnitine biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amino-acid betaine biosynthetic process [inference]

carnitine biosynthetic process

organic substance biosynthetic process [inference]

organonitrogen compound biosynthetic process [inference]

cellular modified amino acid biosynthetic process [inference]

amino-acid betaine biosynthetic process [inference]

carnitine biosynthetic process

cellular metabolic process [inference]

cellular aldehyde metabolic process

cellular modified amino acid metabolic process [inference]

amino-acid betaine metabolic process [inference]

amino-acid betaine biosynthetic process [inference]

carnitine biosynthetic process

carnitine metabolic process [inference]

carnitine biosynthetic process

cellular modified amino acid biosynthetic process [inference]

amino-acid betaine biosynthetic process [inference]

carnitine biosynthetic process

cellular nitrogen compound metabolic process [inference]

amino-acid betaine metabolic process [inference]

amino-acid betaine biosynthetic process [inference]

carnitine biosynthetic process

carnitine metabolic process [inference]

carnitine biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

amino-acid betaine biosynthetic process [inference]

carnitine biosynthetic process

cellular biosynthetic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amino-acid betaine biosynthetic process [inference]

carnitine biosynthetic process

organic substance metabolic process [inference]

cellular aldehyde metabolic process

organonitrogen compound metabolic process [inference]

cellular modified amino acid metabolic process [inference]

amino-acid betaine metabolic process [inference]

amino-acid betaine biosynthetic process [inference]

carnitine biosynthetic process

carnitine metabolic process [inference]

carnitine biosynthetic process

cellular modified amino acid biosynthetic process [inference]

amino-acid betaine biosynthetic process [inference]

carnitine biosynthetic process

organonitrogen compound biosynthetic process [inference]

cellular modified amino acid biosynthetic process [inference]

amino-acid betaine biosynthetic process [inference]

carnitine biosynthetic process

organic substance biosynthetic process [inference]

organonitrogen compound biosynthetic process [inference]

cellular modified amino acid biosynthetic process [inference]

amino-acid betaine biosynthetic process [inference]

carnitine biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular aldehyde metabolic process

cellular modified amino acid metabolic process [inference]

amino-acid betaine metabolic process [inference]

amino-acid betaine biosynthetic process [inference]

carnitine biosynthetic process

carnitine metabolic process [inference]

carnitine biosynthetic process

cellular modified amino acid biosynthetic process [inference]

amino-acid betaine biosynthetic process [inference]

carnitine biosynthetic process

cellular nitrogen compound metabolic process [inference]

amino-acid betaine metabolic process [inference]

amino-acid betaine biosynthetic process [inference]

carnitine biosynthetic process

carnitine metabolic process [inference]

carnitine biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

amino-acid betaine biosynthetic process [inference]

carnitine biosynthetic process

cellular biosynthetic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amino-acid betaine biosynthetic process [inference]

carnitine biosynthetic process

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein homooligomerization [inference]

protein homotetramerization

protein tetramerization [inference]

protein homotetramerization

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein homooligomerization [inference]

protein homotetramerization

protein tetramerization [inference]

protein homotetramerization

Displaying **all 4** entries
GO Term	Evidence Code	PMID
mitochondrion	HTP	34800366
cytosol	TAS
cytoplasm	IDA TAS	1799975 2925663
extracellular exosome	HDA	19056867 23533145

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular membrane-bounded organelle [inference]

mitochondrion

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
aminobutyraldehyde dehydrogenase activity	IBA IDA	1799975 2071588 2925663 8645224
aldehyde dehydrogenase (NAD+) activity	IDA	1799975 2071588 2925663 30914451
4-trimethylammoniobutyraldehyde dehydrogenase activity	EXP IBA IDA	2925663 30914451
glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity
small molecule binding	EXP	30914451

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on the aldehyde or oxo group of donors [inference]

oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [inference]

aldehyde dehydrogenase [NAD(P)+] activity [inference]

aldehyde dehydrogenase (NAD+) activity

binding [inference]

small molecule binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Aldehyde

Functional Category

E: Amino acid transport and metabolism
I: Lipid transport and metabolism
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
oxidoreductase activity

Displaying **all 6** entries
InterPro
Aldehyde dehydrogenase domain
Aldehyde dehydrogenase, C-terminal
Aldehyde dehydrogenase, N-terminal
Aldehyde dehydrogenase, cysteine active site
Aldehyde dehydrogenase, glutamic acid active site
Aldehyde/histidinol dehydrogenase

Human Protein Atlas

ENSG00000143149

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Summary

External Links

Annotation

OrthoDB (Group)