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ALG12 alpha-1,6-mannosyltransferase

Summary

Gene Symbol

Alg12

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

223774

KEGG Gene ID

mmu:223774

PubChem

223774

Alliance of Genome Resources

MGI:2385025

Annotation

Keyword

Endoplasmic reticulum
Glycosyltransferase
Proteomics identification
Reference proteome
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q8VCA2
Q8VDB2	Asparagine-linked glycosylation protein 12 homolog Dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichyl-alpha-1,6-mannosyltransferase Mannosyltransferase ALG12 homolog

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
protein N-linked glycosylation	IBA
dolichol-linked oligosaccharide biosynthetic process	ISO	11983712

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

biosynthetic process [inference]

organic substance biosynthetic process [inference]

carbohydrate derivative biosynthetic process [inference]

oligosaccharide-lipid intermediate biosynthetic process [inference]

dolichol-linked oligosaccharide biosynthetic process

cellular metabolic process [inference]

cellular lipid metabolic process [inference]

oligosaccharide-lipid intermediate biosynthetic process [inference]

dolichol-linked oligosaccharide biosynthetic process

isoprenoid metabolic process [inference]

polyprenol metabolic process [inference]

dolichol metabolic process [inference]

dolichol-linked oligosaccharide biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

oligosaccharide-lipid intermediate biosynthetic process [inference]

dolichol-linked oligosaccharide biosynthetic process

isoprenoid metabolic process [inference]

polyprenol metabolic process [inference]

dolichol metabolic process [inference]

dolichol-linked oligosaccharide biosynthetic process

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

small molecule metabolic process [inference]

alcohol metabolic process [inference]

polyprenol metabolic process [inference]

dolichol metabolic process [inference]

dolichol-linked oligosaccharide biosynthetic process

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein N-linked glycosylation

organic substance metabolic process [inference]

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

oligosaccharide-lipid intermediate biosynthetic process [inference]

dolichol-linked oligosaccharide biosynthetic process

isoprenoid metabolic process [inference]

polyprenol metabolic process [inference]

dolichol metabolic process [inference]

dolichol-linked oligosaccharide biosynthetic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein N-linked glycosylation

carbohydrate derivative metabolic process [inference]

carbohydrate derivative biosynthetic process [inference]

oligosaccharide-lipid intermediate biosynthetic process [inference]

dolichol-linked oligosaccharide biosynthetic process

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

organic substance biosynthetic process [inference]

carbohydrate derivative biosynthetic process [inference]

oligosaccharide-lipid intermediate biosynthetic process [inference]

dolichol-linked oligosaccharide biosynthetic process

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

polyprenol metabolic process [inference]

dolichol metabolic process [inference]

dolichol-linked oligosaccharide biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular lipid metabolic process [inference]

oligosaccharide-lipid intermediate biosynthetic process [inference]

dolichol-linked oligosaccharide biosynthetic process

isoprenoid metabolic process [inference]

polyprenol metabolic process [inference]

dolichol metabolic process [inference]

dolichol-linked oligosaccharide biosynthetic process

Displaying **all 3** entries
GO Term	Evidence Code	PMID
endoplasmic reticulum	IEA
endoplasmic reticulum membrane	IBA
membrane	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

endoplasmic reticulum membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying **all 5** entries
GO Term	Evidence Code	PMID
glycosyltransferase activity	IEA
alpha-1,6-mannosyltransferase activity	IBA
transferase activity	IEA
mannosyltransferase activity	ISO	11983712
dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichol alpha-1,6-mannosyltransferase	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity

glycosyltransferase activity

hexosyltransferase activity [inference]

mannosyltransferase activity

alpha-1,6-mannosyltransferase activity

dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichol alpha-1,6-mannosyltransferase

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K03847

Name

alpha-1,6-mannosyltransferase [EC:2.4.1.260]

References

10336995

Reactions

Displaying 1 entry
KEGG Reaction	Enzyme	Acceptor	Product
R06260	2.4.1.260	G72103RY G74840NI	G48148JS

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0050570	congenital disorder of glycosylation type I	Alliance of Genome Resources
DOID:0080559	congenital disorder of glycosylation Ig	Alliance of Genome Resources

Ortholog

Displaying entries **11 - 20** of 81 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	548874	Xenbase:XB-GENE-5777820
Chrysemys picta bellii	101946366		CHRPI33698
Crocodylus porosus	109315679		CROPO05101
Pseudonaja textilis	113445074		PSETE17911
Meleagris gallopavo	100538714		MELGA00181
Serinus canaria	103813496		SERCA06234
Ornithorhynchus anatinus	100073873		ORNAN06643
Sarcophilus harrisii	100920134		SARHA18584
Erinaceus europaeus	103110262		ERIEU03806
Callithrix jacchus	100392255		CALJA19491

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Summary

External Links

Annotation

KEGG BRITE Database

International Collaboration

Acknowledgements