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aldehyde dehydrogenase 3 family member A2

Summary

Gene Symbol

ALDH3A2

Aliases

FALDH
fatty aldehyde dehydrogenase

Organism

Homo sapiens (human)

External Links

NCBI Gene

224

HGNC

403

KEGG Gene ID

hsa:224

PubChem

224

Alliance of Genome Resources

HGNC:403

Annotation

Keyword

3D-structure
Alternative splicing
Direct protein sequencing
Disease variant
Fatty acid metabolism
Ichthyosis
Intellectual disability
Microsome
NAD
Oxidoreductase
Phosphoprotein
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
P51648	Aldehyde dehydrogenase 10 Fatty aldehyde dehydrogenase Microsomal aldehyde dehydrogenase

Annotation information from UniProt.

Gene Ontology (GO)

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GO Term	Evidence Code	PMID
phytol metabolic process	IMP	15110319
hexadecanal metabolic process	IDA	25047030
epidermis development	IMP	8528251
cellular aldehyde metabolic process	IBA IDA NAS	8528251 9133646
peripheral nervous system development	IMP	8528251

GO Hierarchy

biological process

metabolic process [inference]

cellular metabolic process [inference]

cellular aldehyde metabolic process

hexadecanal metabolic process

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process

cellular lipid metabolic process [inference]

fatty acid metabolic process

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

sesquiterpenoid metabolic process

diterpenoid metabolic process [inference]

phytol metabolic process

primary metabolic process [inference]

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

fatty acid metabolic process

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

sesquiterpenoid metabolic process

diterpenoid metabolic process [inference]

phytol metabolic process

fatty acid derivative metabolic process [inference]

fatty alcohol metabolic process [inference]

phytol metabolic process

small molecule metabolic process [inference]

alcohol metabolic process [inference]

primary alcohol metabolic process [inference]

phytol metabolic process

fatty alcohol metabolic process [inference]

phytol metabolic process

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process

organic substance metabolic process [inference]

cellular aldehyde metabolic process

hexadecanal metabolic process

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

fatty acid metabolic process

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

sesquiterpenoid metabolic process

diterpenoid metabolic process [inference]

phytol metabolic process

fatty acid derivative metabolic process [inference]

fatty alcohol metabolic process [inference]

phytol metabolic process

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

primary alcohol metabolic process [inference]

phytol metabolic process

fatty alcohol metabolic process [inference]

phytol metabolic process

cellular process [inference]

cellular metabolic process [inference]

cellular aldehyde metabolic process

hexadecanal metabolic process

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process

cellular lipid metabolic process [inference]

fatty acid metabolic process

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

sesquiterpenoid metabolic process

diterpenoid metabolic process [inference]

phytol metabolic process

developmental process [inference]

anatomical structure development [inference]

tissue development [inference]

epidermis development

system development [inference]

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GO Term	Evidence Code	PMID
peroxisome	IDA	17510064
endoplasmic reticulum membrane	TAS
intracellular membrane-bounded organelle	IDA	9133646
peroxisomal membrane	TAS
cytosol	TAS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

bounding membrane of organelle [inference]

microbody membrane [inference]

peroxisomal membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle

microbody [inference]

peroxisome

microbody membrane [inference]

peroxisomal membrane

intracellular organelle [inference]

intracellular membrane-bounded organelle

microbody [inference]

peroxisome

microbody membrane [inference]

peroxisomal membrane

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
protein binding	IPI	25047030
medium-chain-aldehyde dehydrogenase activity	IDA	18035827 25047030
aldehyde dehydrogenase (NAD+) activity	IBA IDA IMP	15110319 8528251 9133646
long-chain-alcohol oxidase activity	IDA	18035827
3-chloroallyl aldehyde dehydrogenase activity	IBA

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on CH-OH group of donors [inference]

oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor [inference]

long-chain-alcohol oxidase activity

oxidoreductase activity, acting on the aldehyde or oxo group of donors [inference]

oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [inference]

3-chloroallyl aldehyde dehydrogenase activity

aldehyde dehydrogenase [NAD(P)+] activity [inference]

aldehyde dehydrogenase (NAD+) activity

glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity

binding [inference]

protein binding

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

aldehyde dehydrogenase

Functional Category

C: Energy production and conversion
E: Amino acid transport and metabolism
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
3-chloroallyl aldehyde dehydrogenase activity
aldehyde dehydrogenase (NAD+) activity
cellular aldehyde metabolic process
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
oxidoreductase activity

Displaying **all 5** entries
InterPro
Aldehyde dehydrogenase NAD(P)-dependent
Aldehyde dehydrogenase domain
Aldehyde dehydrogenase, C-terminal
Aldehyde dehydrogenase, N-terminal
Aldehyde/histidinol dehydrogenase

Human Protein Atlas

ENSG00000072210

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

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Summary

External Links

Annotation

OrthoDB (Group)