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protein O-glucosyltransferase 1

Summary

Gene Symbol

Poglut1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

224143

KEGG Gene ID

mmu:224143

PubChem

224143

Alliance of Genome Resources

MGI:2444232

Annotation

Keyword

Disulfide bond
Endoplasmic reticulum
Gastrulation
Glycoprotein
Glycosyltransferase
Reference proteome
Signal

Proteins

Displaying **all 3** entries
UniProt	Protein Name
Q8BV60
Q8BLG5
Q8BYB9	CAP10-like 46 kDa protein KTEL motif-containing protein 1 O-glucosyltransferase Rumi homolog Protein O-xylosyltransferase POGLUT1 Wing-shaped neural plate protein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
protein O-linked glycosylation	IBA IMP ISO	21490058
somitogenesis	IMP	9636176
circulatory system development	IMP	21490058
muscle tissue development	ISO
positive regulation of Notch signaling pathway	IBA IMP ISO	26496195

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

protein O-linked glycosylation via serine

peptidyl-amino acid modification [inference]

peptidyl-serine modification [inference]

protein O-linked glycosylation via serine

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

protein O-linked glycosylation via serine

peptidyl-amino acid modification [inference]

peptidyl-serine modification [inference]

protein O-linked glycosylation via serine

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein O-linked glycosylation

protein O-linked glycosylation via serine

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

protein O-linked glycosylation via serine

peptidyl-amino acid modification [inference]

peptidyl-serine modification [inference]

protein O-linked glycosylation via serine

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

protein O-linked glycosylation via serine

peptidyl-amino acid modification [inference]

peptidyl-serine modification [inference]

protein O-linked glycosylation via serine

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein O-linked glycosylation

protein O-linked glycosylation via serine

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

protein O-linked glycosylation via serine

peptidyl-amino acid modification [inference]

peptidyl-serine modification [inference]

protein O-linked glycosylation via serine

multicellular organismal process [inference]

multicellular organism development

pattern specification process [inference]

regionalization [inference]

anterior/posterior pattern specification [inference]

somitogenesis

segmentation [inference]

somitogenesis

developmental process [inference]

anatomical structure morphogenesis [inference]

embryonic morphogenesis [inference]

gastrulation

anatomical structure formation involved in morphogenesis [inference]

somitogenesis

anatomical structure development [inference]

multicellular organism development

tissue development [inference]

mesoderm development [inference]

mesenchyme development [inference]

paraxial mesoderm development

muscle tissue development

system development [inference]

circulatory system development

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of Notch signaling pathway

positive regulation of Notch signaling pathway

positive regulation of signal transduction [inference]

positive regulation of Notch signaling pathway

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of Notch signaling pathway

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of Notch signaling pathway

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of Notch signaling pathway

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of Notch signaling pathway

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of Notch signaling pathway

positive regulation of Notch signaling pathway

positive regulation of signal transduction [inference]

positive regulation of Notch signaling pathway

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of Notch signaling pathway

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of gastrulation

regulation of multicellular organismal development [inference]

regulation of embryonic development [inference]

regulation of gastrulation

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of Notch signaling pathway

positive regulation of Notch signaling pathway

positive regulation of signal transduction [inference]

positive regulation of Notch signaling pathway

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of Notch signaling pathway

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of Notch signaling pathway

regulation of multicellular organismal process [inference]

regulation of multicellular organismal development [inference]

regulation of embryonic development [inference]

regulation of gastrulation

Displaying **all 3** entries
GO Term	Evidence Code	PMID
endoplasmic reticulum lumen	ISO TAS
endoplasmic reticulum	ISO
endomembrane system	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

endomembrane system

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

endoplasmic reticulum lumen

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying entries **6 - 8** of 8 in total

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GO Term	Evidence Code	PMID
protein binding	IPI	26496195
EGF-domain serine glucosyltransferase activity	IEA
UDP-glucosyltransferase activity	IBA IDA ISO TAS	21949356 26496195

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity

glycosyltransferase activity

UDP-glycosyltransferase activity [inference]

UDP-glucosyltransferase activity

EGF-domain serine glucosyltransferase activity

UDP-xylosyltransferase activity

EGF-domain serine xylosyltransferase activity

hexosyltransferase activity [inference]

glucosyltransferase activity

UDP-glucosyltransferase activity

EGF-domain serine glucosyltransferase activity

pentosyltransferase activity [inference]

xylosyltransferase activity [inference]

UDP-xylosyltransferase activity

EGF-domain serine xylosyltransferase activity

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K13667

Name

EGF-domain serine glucosyl/xylosyltransferase [EC:2.4.1.376 2.4.2.63]

References

Rhea

RHEA:58116

UDP-α-D-glucose

H⁺ + UDP

Enzyme

2.4.1.376

PMID

RHEA:62016

UDP-α-D-xylose

H⁺ + UDP

Enzyme

2.4.2.63

PMID

Disease

Disease Ontology

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:0060256	Dowling-Degos disease	Alliance of Genome Resources
DOID:0080762	autosomal recessive limb-girdle muscular dystrophy type 2Z	Alliance of Genome Resources
DOID:0110274	autosomal recessive limb-girdle muscular dystrophy	Alliance of Genome Resources

Ortholog

Displaying entries **21 - 30** of 69 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Pongo abelii	100442484		PONAB26094
Homo sapiens	56983	HGNC:22954	HUMAN71689
Ursus americanus	123784033		URSAM15944
Ailuropoda melanoleuca	100480912		AILME16827
Mustela putorius furo	101674307		MUSPF04651
Felis catus	101088101		FELCA23209
Panthera leo	122198598		PANLE24404
Tursiops truncatus	101316875		TURTR11449
Balaenoptera musculus	118894693		BALMU18280
Loxodonta africana	100661725		LOXAF11228