GlyCosmos Portal

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GO Term	Evidence Code	PMID
protein binding	IPI	15231747 17043677 23125361 25220460 26496610 26700805 26779609 29961565 31413325 32296183 32814053 33961781 34591612
5'-3' RNA exonuclease activity	IBA TAS	10409438
transcription termination site sequence-specific DNA binding	IDA	21700224
3'-5'-RNA exonuclease activity	EXP	23482395
nuclease activity	TAS	10409438

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

nuclease activity

exonuclease activity [inference]

RNA exonuclease activity [inference]

RNA exonuclease activity, producing 5'-phosphomonoesters [inference]

3'-5' exonuclease activity [inference]

3'-5'-RNA exonuclease activity

5'-3' exonuclease activity

5'-3' RNA exonuclease activity

exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters [inference]

RNA exonuclease activity, producing 5'-phosphomonoesters [inference]

RNA nuclease activity [inference]

RNA exonuclease activity [inference]

RNA exonuclease activity, producing 5'-phosphomonoesters [inference]

catalytic activity, acting on a nucleic acid [inference]

catalytic activity, acting on RNA [inference]

RNA nuclease activity [inference]

RNA exonuclease activity [inference]

RNA exonuclease activity, producing 5'-phosphomonoesters [inference]

binding [inference]

protein binding

identical protein binding

ion binding [inference]

cation binding [inference]

metal ion binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

transcription regulatory region nucleic acid binding [inference]

transcription cis-regulatory region binding [inference]

transcription termination site sequence-specific DNA binding

DNA binding [inference]

double-stranded DNA binding [inference]

sequence-specific double-stranded DNA binding [inference]

transcription cis-regulatory region binding [inference]

transcription termination site sequence-specific DNA binding

sequence-specific DNA binding [inference]

sequence-specific double-stranded DNA binding [inference]

transcription cis-regulatory region binding [inference]

transcription termination site sequence-specific DNA binding

RNA binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

5'-3 exoribonuclease

Functional Category

E: Amino acid transport and metabolism
J: Translation, ribosomal structure and biogenesis
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
5'-3' RNA exonuclease activity
hydrolase activity
nuclease activity

Displaying **all 3** entries
InterPro
5'-3' exoribonuclease
Xrn1, N-terminal
Xrn1, helical domain

Disease

Disease Ontology

Displaying **all 4** entries
DO ID	Disease Name	Source
DOID:0080202	adenoid cystic carcinoma	Alliance of Genome Resources
DOID:1324	lung cancer	Alliance of Genome Resources
DOID:1824	status epilepticus	Alliance of Genome Resources
DOID:1967	leiomyosarcoma	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 88 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Mus musculus	24128		MGI:894687	MOUSE35886
Drosophila melanogaster	33964		FB:FBgn0031868
Caenorhabditis elegans	175071		WB:WBGene00006964
Danio rerio	321940		ZFIN:ZDB-GENE-040426-2874	DANRE19678
Rattus norvegicus	362229		RGD:1310218	RATNO26265
Pan troglodytes	458131	9598_0:0051b9		PANTR24479
Canis lupus familiaris	477133			CANLF09250
Bos taurus	517417			BOVIN04588
Macaca mulatta	700934			MACMU01667
Xenopus tropicalis	733834		Xenbase:XB-GENE-993157

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements