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heat shock protein family A (Hsp70) member 4 like

Summary

Gene Symbol

HSPA4L

Organism

Homo sapiens (human)

External Links

NCBI Gene

22824

PubChem

22824

Alliance of Genome Resources

HGNC:17041

Annotation

Keyword

ATP-binding
Chaperone
Cytoplasm
Nucleus
Phosphoprotein
Proteomics identification
Reference proteome
Stress response

Proteins

Displaying **all 5** entries
UniProt	Protein Name
O95757	Heat shock 70-related protein APG-1 Heat shock protein family H member 3 Heat-shock protein family A member 4-like protein Osmotic stress protein 94
E9PDE8
B4DXT2
B4DZR0
A0A140VKE7

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein folding	ISS
protein folding	IBA
response to unfolded protein	ISS

GO Hierarchy

biological process

cellular process [inference]

protein folding

response to stimulus [inference]

response to stress [inference]

response to topologically incorrect protein [inference]

response to unfolded protein

response to chemical [inference]

response to organic substance [inference]

response to topologically incorrect protein [inference]

response to unfolded protein

Displaying **all 5** entries
GO Term	Evidence Code	PMID
nucleus	ISS
nucleus	IBA
cytoplasm	ISS
cytosol	IDA	21231916
cytosol	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying **all 3** entries
GO Term	Evidence Code	PMID
adenyl-nucleotide exchange factor activity	IBA
ATP binding	ISS
ATP-dependent protein folding chaperone	IEA

GO Hierarchy

molecular function

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl-nucleotide exchange factor activity

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl-nucleotide exchange factor activity

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

protein folding chaperone [inference]

ATP-dependent protein folding chaperone

molecular function regulator activity [inference]

ATPase regulator activity [inference]

adenyl-nucleotide exchange factor activity

ATP-dependent activity [inference]

ATP-dependent protein folding chaperone

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

heat shock

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
ATP binding
ATP-dependent protein folding chaperone
nucleotide binding

Displaying **all 5** entries
InterPro
ATPase, nucleotide binding domain
Heat shock protein 70 family
Heat shock protein 70, conserved site
Heat shock protein 70kD, C-terminal domain superfamily
Heat shock protein 70kD, peptide-binding domain superfamily

Ortholog

Displaying entries **1 - 10** of 86 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Saccharomyces cerevisiae S288C	3308	SGD:S000006027
Saccharomyces cerevisiae S288C	10808	SGD:S000006027
Saccharomyces cerevisiae S288C	15505	SGD:S000006027
Mus musculus	18415	ZFIN:ZDB-GENE-030131-2412	MOUSE37178
Danio rerio	22824	ZFIN:ZDB-GENE-030131-2412
Danio rerio	39557	ZFIN:ZDB-GENE-030131-2412
Canis lupus familiaris	476089		CANLF06265
Danio rerio	562019		DANRE12604
Macaca mulatta	710143		MACMU37271
Pan troglodytes	742975		PANTR34447