GlyCosmos Portal

GlyTouCan

Glycan Structure Repository

GlyComb

Glycoconjugate Repository

GlycoPOST

Glycomics MS raw data Repository

UniCarb-DR

Glycomics MS Repository for glycan annotations from GlycoWorkbench

All Resources

Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms

Other Information

Release Statistics Download

Tools

Glycan Converters

LM-GlycomeAtlas

Search Tools

Cross Search Glycan Search Publication Search Programmatic Access

dolichol kinase

Summary

Gene Symbol

DOLK

Aliases

DK1
KIAA1094
dolichol kinase 1

Organism

Homo sapiens (human)

External Links

NCBI Gene

22845

HGNC

23406

KEGG Gene ID

hsa:22845

PubChem

22845

Alliance of Genome Resources

HGNC:23406

Annotation

Keyword

Congenital disorder of glycosylation
Disease variant
Endoplasmic reticulum
Kinase
Lipid metabolism
Reference proteome
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q9UPQ8	Transmembrane protein 15
A0A0S2Z597

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
dolichyl monophosphate biosynthetic process	IBA IDA	12213788 16923818
dolichyl diphosphate biosynthetic process

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

dolichyl diphosphate metabolic process [inference]

dolichyl diphosphate biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

dolichyl diphosphate metabolic process [inference]

dolichyl diphosphate biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

dolichyl diphosphate metabolic process [inference]

dolichyl diphosphate biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

dolichyl diphosphate metabolic process [inference]

dolichyl diphosphate biosynthetic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

dolichyl diphosphate metabolic process [inference]

dolichyl diphosphate biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

dolichyl diphosphate metabolic process [inference]

dolichyl diphosphate biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

cellular process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

dolichyl diphosphate metabolic process [inference]

dolichyl diphosphate biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

dolichyl diphosphate metabolic process [inference]

dolichyl diphosphate biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

dolichyl diphosphate metabolic process [inference]

dolichyl diphosphate biosynthetic process

Displaying 1 entry
GO Term	Evidence Code	PMID
endoplasmic reticulum membrane	IBA IDA TAS	16923818

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

Displaying **all 2** entries
GO Term	Evidence Code	PMID
dolichol kinase activity	IBA IDA TAS	12213788 16923818
protein binding	IPI	25416956 26871637 28514442 32296183

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

dolichol kinase activity

phosphotransferase activity, alcohol group as acceptor [inference]

dolichol kinase activity

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K00902

Name

dolichol kinase [EC:2.7.1.108]

References

12213788

Rhea

CTP

H⁺ + CDP

Enzyme

2.7.1.108

PMID

Disease

Disease Ontology

Displaying entries **1 - 10** of 58 in total

1

2

3

4

5

6

Next ›

Last »
DO ID	Disease Name	Source
DOID:0050428	nonepidermolytic palmoplantar keratoderma	DisGeNET
DOID:0050570	congenital disorder of glycosylation type I	DisGeNET Alliance of Genome Resources
DOID:0080212	polycystic kidney disease 4	DisGeNET
DOID:0080565	congenital disorder of glycosylation Im	Glyco-Disease Genes Database DisGeNET Alliance of Genome Resources
DOID:0080568	congenital disorder of glycosylation Iq	DisGeNET
DOID:0110423	dilated cardiomyopathy 1C	DisGeNET
DOID:0110424	dilated cardiomyopathy 1CC	DisGeNET
DOID:0110425	dilated cardiomyopathy 1A	DisGeNET
DOID:0110426	dilated cardiomyopathy 1D	DisGeNET
DOID:0110427	dilated cardiomyopathy 1V	DisGeNET

The Human Phenotype Ontology

Displaying entries **21 - 30** of 55 in total

« First

‹ Prev

1

2

3

4

5

6

Next ›

Last »
HPO ID	HPO Term
HP:0001635	Congestive heart failure
HP:0001644	Dilated cardiomyopathy
HP:0001662	Bradycardia
HP:0001727	Thromboembolic stroke
HP:0001985	Hypoketotic hypoglycemia
HP:0002013	Vomiting
HP:0002014	Diarrhea
HP:0002069	Bilateral tonic-clonic seizure
HP:0002445	Tetraplegia
HP:0002521	Hypsarrhythmia

Displaying **all 3** entries
Disease ID	Disease Name
ORPHA:154	dilated cardiomyopathy 1KK obsolete familial isolated dilated cardiomyopathy
ORPHA:91131	DK1-congenital disorder of glycosylation
OMIM:610768	DK1-congenital disorder of glycosylation

PubChem Disease

GHR Health Conditions

DOLK-congenital disorder of glycosylation

MedGen Diseases

DK1-congenital disorder of glycosylation

OMIM Phenotypes

CONGENITAL DISORDER OF GLYCOSYLATION, TYPE Im; CDG1M

KEGG Diseases

Congenital disorders of glycosylation type I

Gene-Disease-Co-Occurrences-in-Literature (PubChem)

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP006686
Gene Name: dolichol kinase

Ortholog

Displaying entries **31 - 40** of 86 in total

« First

‹ Prev

1

2

3

4

5

6

7

8

9

Next ›

Last »
Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Mustela putorius furo	101675215		MUSPF11555
Felis catus	101083720		FELCA29407
Panthera leo	122204435		PANLE25734
Balaenoptera musculus	118896715		BALMU13969
Loxodonta africana	100662271		LOXAF17023
Equus caballus	100070129		HORSE23659
Equus caballus	100146151		HORSE23659
Sus scrofa	100152320		PIGXX16303
Bos taurus	526844		BOVIN03265
Capra hircus	102182047		CAPHI02476

About Release Notes Help Feedback

Click here to visit the beta site.

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

Logo License Policies Site Map

Contact: support@glycosmos.org

GlyCosmos Portal v4.0.0

Last updated: August 19, 2024