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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
neuroligin 1
Summary
- Gene Symbol
-
- NLGN1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Autism
- Biological rhythms
- Cell adhesion
- Cell membrane
- Disease variant
- Disulfide bond
- Glycoprotein
- Reference proteome
- Secreted
- Signal
- Synapse
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| Q8N2Q7 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| positive regulation of synaptic vesicle exocytosis | ||
| positive regulation of ruffle assembly | ||
| positive regulation of excitatory postsynaptic potential | ||
| synapse assembly | ||
| positive regulation of synaptic transmission, glutamatergic |
GO Hierarchy
- rhythmic process
biological process
cellular process [inference]
response to stimulus [inference]
localization [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of signaling [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of cellular component biogenesis [inference]
positive regulation of cellular process [inference]
regulation of cellular component organization [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| membrane | ||
| postsynaptic membrane | ||
| Golgi apparatus | ||
| filopodium tip | ||
| postsynaptic density |
| GO Term | Evidence Code | PMID |
|---|---|---|
| identical protein binding | ||
| neurexin family protein binding | ||
| signaling receptor activity | ||
| PDZ domain binding | ||
| scaffold protein binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- hydrolase
- Functional Category
-
- E: Amino acid transport and metabolism
- Q: Secondary metabolites biosynthesis, transport and catabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| hydrolase activity |
| InterPro |
|---|
| Alpha/Beta hydrolase fold |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060041 | autism spectrum disorder | |
| DOID:12849 | autistic disorder | |
| DOID:1824 | status epilepticus |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 33962 | FB:FBgn0031866 | |||
| 40912 | FB:FBgn0083963 | |||
| 40913 | FB:FBgn0051146 | |||
| 42402 | FB:FBgn0083975 | |||
| 116647 | RGD:621117 | RATNO24905 | ||
| 181484 | WB:WBGene00006412 | |||
| 192167 | MGI:2179435 | MOUSE38558 | ||
| 470999 | 9598_0:0011b9 | PANTR32669 | ||
| 530042 | BOVIN14983 | |||
| 693541 | MACMU28514 |
