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MIRAGE
purinergic receptor P2X 2

Summary
Gene Symbol
  • P2RX2
Organism
Homo sapiens (human)
NCBI Gene
22953
PubChem
22953
Alliance of Genome Resources
JoGo
P2RX2
TogoVar
P2RX2
Annotation
Keyword
  • ATP-binding
  • Alternative splicing
  • Cell membrane
  • Disease variant
  • Disulfide bond
  • Glycoprotein
  • Hearing
  • Ligand-gated ion channel
  • Non-syndromic deafness
  • Proteomics identification
  • Receptor
  • Reference proteome
  • Transmembrane helix
Proteins
Displaying all 2 entries
UniProt Protein Name
Q32MC3
  • ATP receptor
  • Purinergic receptor
Q9UBL9
  • ATP receptor
  • Purinergic receptor
Annotation information from UniProt.
Gene Ontology (GO)
Displaying entries 1 - 5 of 18 in total
GO Term Evidence Code PMID
response to hypoxia
response to ischemia
detection of hypoxic conditions in blood by carotid body chemoreceptor signaling
neuromuscular synaptic transmission
neuromuscular junction development
GO Hierarchy
Displaying entries 1 - 5 of 7 in total
GO Term Evidence Code PMID
purinergic nucleotide receptor activity
extracellularly ATP-gated monoatomic cation channel activity
extracellularly ATP-gated monoatomic cation channel activity
extracellularly ATP-gated monoatomic cation channel activity
ATP binding
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
Disease
Disease Ontology
Displaying 1 entry
DO ID Disease Name Source
DOID:0110567 autosomal dominant nonsyndromic deafness 41
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026