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endoplasmic reticulum protein 44

Summary

Gene Symbol

ERP44

Organism

Homo sapiens (human)

External Links

NCBI Gene

23071

PubChem

23071

Alliance of Genome Resources

HGNC:18311

Annotation

Keyword

3D-structure
Chaperone
Direct protein sequencing
Disulfide bond
Endoplasmic reticulum
Reference proteome
Signal
Stress response

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A384MEE7
Q9BS26	Thioredoxin domain-containing protein 4

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
protein folding	IBA IDA	11847130
glycoprotein metabolic process	IDA	11847130
cell redox homeostasis	TAS	11847130
response to unfolded protein	IDA	11847130
response to endoplasmic reticulum stress	IDA	11847130

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process

primary metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process

carbohydrate derivative metabolic process [inference]

glycoprotein metabolic process

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process

cellular process [inference]

protein folding

cellular response to stimulus [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress

homeostatic process [inference]

cellular homeostasis [inference]

cell redox homeostasis

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress

response to topologically incorrect protein [inference]

response to unfolded protein

response to chemical [inference]

response to organic substance [inference]

response to topologically incorrect protein [inference]

response to unfolded protein

cellular response to stimulus [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
specific granule lumen	TAS
endoplasmic reticulum membrane	IBA IDA	11847130
endoplasmic reticulum lumen	IDA	11847130
extracellular region	TAS
cell surface	IDA	19995400

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

membrane-enclosed lumen [inference]

organelle lumen [inference]

vesicle lumen [inference]

cytoplasmic vesicle lumen [inference]

secretory granule lumen [inference]

specific granule lumen

intracellular organelle lumen [inference]

endoplasmic reticulum lumen

cytoplasmic vesicle lumen [inference]

secretory granule lumen [inference]

specific granule lumen

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum-Golgi intermediate compartment

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum-Golgi intermediate compartment

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying **all 2** entries
GO Term	Evidence Code	PMID
protein binding	IPI	17805346 29858230 32814053
protein disulfide isomerase activity	IBA IDA	11847130

GO Hierarchy

molecular function

catalytic activity [inference]

isomerase activity [inference]

intramolecular oxidoreductase activity [inference]

intramolecular oxidoreductase activity, transposing S-S bonds [inference]

protein disulfide isomerase activity

catalytic activity, acting on a protein [inference]

protein disulfide isomerase activity

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Endoplasmic reticulum resident protein 44

Functional Category

C: Energy production and conversion
E: Amino acid transport and metabolism
M: Cell wall/membrane/envelope biogenesis

Displaying **all 3** entries
InterPro
Endoplasmic reticulum resident protein 44, TRX-like domain b'
Thioredoxin domain
Thioredoxin-like superfamily

Ortholog

Displaying entries **1 - 10** of 80 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	32588	FB:FBgn0030734
Drosophila melanogaster	40883	FB:FBgn0037498
Mus musculus	76299	MGI:1923549	MOUSE43065
Caenorhabditis elegans	172191	WB:WBGene00016278
Caenorhabditis elegans	177572	WB:WBGene00015510
Caenorhabditis elegans	185676	WB:WBGene00018358
Rattus norvegicus	298066	RGD:1309176	RATNO34311
Danio rerio	393866	ZFIN:ZDB-GENE-040426-1902	DANRE11297
Xenopus laevis	399233	Xenbase:XB-GENE-962194
Pan troglodytes	464616		PANTR44468