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tripartite motif containing 35

Summary

Gene Symbol

TRIM35

Organism

Homo sapiens (human)

External Links

NCBI Gene

23087

PubChem

23087

Alliance of Genome Resources

HGNC:16285

JoGo

TRIM35

TogoVar

TRIM35

Annotation

Keyword

Acetylation
Alternative splicing
Apoptosis
Coiled coil
Cytoplasm
Nucleus
Phosphoprotein
Proteomics identification
Reference proteome
Transferase
Ubl conjugation pathway
Zinc-finger

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q9UPQ4	Hemopoietic lineage switch protein 5
E5RGB3

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

1

2

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Last »
GO Term	Evidence Code	PMID
apoptotic process	IEA
protein ubiquitination	IEA
positive regulation of apoptotic process	IDA	14662771
positive regulation of apoptotic process	IBA
suppression of viral release by host	IDA	18248090

GO Hierarchy

biological process

immune system process [inference]

immune response [inference]

innate immune response

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

macromolecule modification [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

cellular process [inference]

cell death [inference]

programmed cell death [inference]

apoptotic process

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to virus [inference]

defense response to virus [inference]

suppression of viral release by host

defense response to other organism [inference]

innate immune response

defense response to symbiont [inference]

defense response to virus [inference]

suppression of viral release by host

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

innate immune response

defense response to symbiont [inference]

defense response to virus [inference]

suppression of viral release by host

immune response [inference]

innate immune response

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to virus [inference]

defense response to virus [inference]

suppression of viral release by host

defense response to other organism [inference]

innate immune response

defense response to symbiont [inference]

defense response to virus [inference]

suppression of viral release by host

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to virus [inference]

defense response to virus [inference]

suppression of viral release by host

defense response to other organism [inference]

innate immune response

defense response to symbiont [inference]

defense response to virus [inference]

suppression of viral release by host

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cell cycle [inference]

negative regulation of mitotic cell cycle

regulation of cellular process [inference]

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

positive regulation of apoptotic process

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process

positive regulation of cellular process [inference]

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process

negative regulation of cellular process [inference]

negative regulation of cell cycle [inference]

negative regulation of mitotic cell cycle

regulation of cell cycle [inference]

regulation of mitotic cell cycle [inference]

negative regulation of mitotic cell cycle

negative regulation of cell cycle [inference]

negative regulation of mitotic cell cycle

Displaying **all 3** entries
GO Term	Evidence Code	PMID
nucleus	ISS
cytoplasm	ISS
cytoplasm	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein binding	IPI	32296183 32814053
zinc ion binding	IEA
ubiquitin protein ligase activity	IBA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

acyltransferase activity [inference]

aminoacyltransferase activity [inference]

ubiquitin-like protein transferase activity [inference]

ubiquitin-protein transferase activity [inference]

ubiquitin protein ligase activity

ubiquitin-like protein ligase activity [inference]

ubiquitin protein ligase activity

catalytic activity, acting on a protein [inference]

ubiquitin-like protein transferase activity [inference]

ubiquitin-protein transferase activity [inference]

ubiquitin protein ligase activity

ubiquitin-like protein ligase activity [inference]

ubiquitin protein ligase activity

binding [inference]

protein binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

zinc ion binding

Gene Ontology information from NCBI Gene and UniProt.

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

GlyCosmos Portal v4.5.0

Last updated: April 6, 2026

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