GlyCosmos Portal

Submissions

spartin

Summary

Gene Symbol

SPART

Organism

Homo sapiens (human)

External Links

NCBI Gene

23111

PubChem

23111

Alliance of Genome Resources

HGNC:18514

JoGo

SPART

TogoVar

SPART

Annotation

Keyword

3D-structure
Acetylation
Cytoplasm
Disease variant
Hereditary spastic paraplegia
Isopeptide bond
Lipid degradation
Lipid droplet
Lipid transport
Lipid-binding
Phosphoprotein
Proteomics identification
Reference proteome
Ubl conjugation

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q8N0X7	Spastic paraplegia 20 protein Trans-activated by hepatitis C virus core protein 1
A0A024RDV9

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 14 in total

1

2

3

Next ›

Last »
GO Term	Evidence Code	PMID
lipid transport	IDA	38190532
lipid catabolic process	IEA
BMP signaling pathway	IEA
negative regulation of BMP signaling pathway	IBA
lipid droplet organization	IEA

GO Hierarchy

biological process

metabolic process [inference]

catabolic process [inference]

cellular catabolic process [inference]

autophagy [inference]

macroautophagy [inference]

lipophagy

organic substance catabolic process [inference]

lipid catabolic process

cellular metabolic process [inference]

cellular catabolic process [inference]

autophagy [inference]

macroautophagy [inference]

lipophagy

primary metabolic process [inference]

lipid metabolic process [inference]

lipid catabolic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

lipid catabolic process

organic substance catabolic process [inference]

lipid catabolic process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

BMP signaling pathway

cell growth [inference]

developmental cell growth [inference]

collateral sprouting [inference]

collateral sprouting in absence of injury

cell cycle process [inference]

cytokinetic process [inference]

mitotic cytokinetic process [inference]

midbody abscission

mitotic cell cycle process [inference]

mitotic cytokinetic process [inference]

midbody abscission

cellular metabolic process [inference]

cellular catabolic process [inference]

autophagy [inference]

macroautophagy [inference]

lipophagy

cell division

process utilizing autophagic mechanism [inference]

autophagy [inference]

macroautophagy [inference]

lipophagy

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

lipid droplet organization

membrane organization [inference]

midbody abscission

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

neuromuscular process

developmental process [inference]

anatomical structure development [inference]

tissue development [inference]

connective tissue development [inference]

adipose tissue development

growth [inference]

cell growth [inference]

developmental cell growth [inference]

collateral sprouting [inference]

collateral sprouting in absence of injury

developmental growth [inference]

developmental cell growth [inference]

collateral sprouting [inference]

collateral sprouting in absence of injury

developmental growth involved in morphogenesis [inference]

collateral sprouting [inference]

collateral sprouting in absence of injury

localization [inference]

establishment of localization [inference]

transport [inference]

organic substance transport [inference]

lipid transport

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

regulation of BMP signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

regulation of growth [inference]

regulation of cell growth [inference]

negative regulation of cell growth [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

regulation of extent of cell growth [inference]

regulation of collateral sprouting [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

regulation of collateral sprouting in absence of injury [inference]

negative regulation of collateral sprouting in absence of injury

negative regulation of growth [inference]

negative regulation of cell growth [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

negative regulation of developmental growth [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

regulation of developmental growth [inference]

negative regulation of developmental growth [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

regulation of collateral sprouting [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

regulation of collateral sprouting in absence of injury [inference]

negative regulation of collateral sprouting in absence of injury

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of growth [inference]

negative regulation of cell growth [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

negative regulation of developmental growth [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of cell growth [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

negative regulation of cellular component organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development [inference]

negative regulation of axonogenesis [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of cellular response to growth factor stimulus [inference]

negative regulation of BMP signaling pathway

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

negative regulation of developmental growth [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

negative regulation of nervous system development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

negative regulation of multicellular organismal process [inference]

negative regulation of nervous system development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

regulation of BMP signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of cellular response to growth factor stimulus [inference]

negative regulation of BMP signaling pathway

regulation of cellular response to growth factor stimulus [inference]

regulation of BMP signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of cellular response to growth factor stimulus [inference]

negative regulation of BMP signaling pathway

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of axonogenesis [inference]

regulation of collateral sprouting [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

regulation of collateral sprouting in absence of injury [inference]

negative regulation of collateral sprouting in absence of injury

negative regulation of axonogenesis [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

regulation of cell differentiation [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

regulation of cell development [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

regulation of neurogenesis [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

regulation of developmental growth [inference]

negative regulation of developmental growth [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

regulation of collateral sprouting [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

regulation of collateral sprouting in absence of injury [inference]

negative regulation of collateral sprouting in absence of injury

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

negative regulation of developmental growth [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

negative regulation of nervous system development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of neurogenesis [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

negative regulation of nervous system development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

BMP signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

regulation of BMP signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

regulation of cell differentiation [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

regulation of cell development [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

regulation of neurogenesis [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of cell growth [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

negative regulation of cellular component organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development [inference]

negative regulation of axonogenesis [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

regulation of cellular component organization [inference]

regulation of cell growth [inference]

negative regulation of cell growth [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

regulation of extent of cell growth [inference]

regulation of collateral sprouting [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

regulation of collateral sprouting in absence of injury [inference]

negative regulation of collateral sprouting in absence of injury

regulation of cell projection organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development [inference]

negative regulation of axonogenesis [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

regulation of plasma membrane bounded cell projection organization [inference]

regulation of neuron projection development [inference]

negative regulation of neuron projection development [inference]

negative regulation of axonogenesis [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

regulation of axonogenesis [inference]

regulation of collateral sprouting [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

regulation of collateral sprouting in absence of injury [inference]

negative regulation of collateral sprouting in absence of injury

negative regulation of axonogenesis [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

negative regulation of cellular component organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development [inference]

negative regulation of axonogenesis [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

regulation of multicellular organismal process [inference]

negative regulation of multicellular organismal process [inference]

negative regulation of nervous system development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of neurogenesis [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

negative regulation of nervous system development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

regulation of biological quality [inference]

regulation of membrane potential [inference]

regulation of mitochondrial membrane potential

Displaying entries **1 - 5** of 8 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
cytoplasm	IDA	19580544
mitochondrial outer membrane	IDA	21559443
lipid droplet	IDA	37443287 38190532
cytosol	IDA
plasma membrane	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

outer membrane [inference]

organelle outer membrane [inference]

mitochondrial outer membrane

organelle membrane [inference]

mitochondrial membrane [inference]

mitochondrial outer membrane

bounding membrane of organelle [inference]

organelle outer membrane [inference]

mitochondrial outer membrane

cell junction [inference]

synapse

midbody

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

lipid droplet

intracellular organelle [inference]

intracellular membrane-bounded organelle

intracellular non-membrane-bounded organelle [inference]

lipid droplet

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein binding	IPI	20719964 32296183 32814053 37443287
lipid binding	IDA	38190532
ubiquitin protein ligase binding	IPI	19580544

GO Hierarchy

molecular function

binding [inference]

protein binding

enzyme binding [inference]

ubiquitin-like protein ligase binding [inference]

ubiquitin protein ligase binding

lipid binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Spartin

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
cell division

Displaying **all 4** entries
InterPro
MIT domain superfamily
MIT domain
Senescence/spartin-associated, C-terminal
Spartin-like

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0050886	Troyer syndrome	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements