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abraxas 2, BRISC complex subunit

Summary

Gene Symbol

ABRAXAS2

Organism

Homo sapiens (human)

External Links

NCBI Gene

23172

PubChem

23172

Alliance of Genome Resources

HGNC:28975

Annotation

Keyword

3D-structure
Coiled coil
Cytoskeleton
Microtubule
Mitosis
Nucleus
Phosphoprotein
Reference proteome
Ubl conjugation pathway

Proteins

Displaying 1 entry
UniProt	Protein Name
Q15018	Abraxas brother protein 1 Protein FAM175B

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
response to ischemia	IMP	21195082
mitotic cell cycle	IMP	26195665
protein K63-linked deubiquitination	IMP	24075985 26195665
attachment of spindle microtubules to kinetochore	IBA IMP	26195665
cell division	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein removal [inference]

protein deubiquitination [inference]

protein K63-linked deubiquitination

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein removal [inference]

protein deubiquitination [inference]

protein K63-linked deubiquitination

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein removal [inference]

protein deubiquitination [inference]

protein K63-linked deubiquitination

macromolecule modification [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein removal [inference]

protein deubiquitination [inference]

protein K63-linked deubiquitination

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein removal [inference]

protein deubiquitination [inference]

protein K63-linked deubiquitination

cellular process [inference]

microtubule-based process [inference]

microtubule cytoskeleton organization [inference]

spindle organization [inference]

mitotic spindle organization [inference]

mitotic spindle assembly

spindle assembly [inference]

mitotic spindle assembly

microtubule cytoskeleton organization involved in mitosis [inference]

mitotic spindle organization [inference]

mitotic spindle assembly

cell cycle [inference]

mitotic cell cycle

cell cycle process [inference]

spindle organization [inference]

mitotic spindle organization [inference]

mitotic spindle assembly

spindle assembly [inference]

mitotic spindle assembly

mitotic cell cycle process [inference]

microtubule cytoskeleton organization involved in mitosis [inference]

mitotic spindle organization [inference]

mitotic spindle assembly

cell division

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

microtubule cytoskeleton organization [inference]

spindle organization [inference]

mitotic spindle organization [inference]

mitotic spindle assembly

spindle assembly [inference]

mitotic spindle assembly

microtubule cytoskeleton organization involved in mitosis [inference]

mitotic spindle organization [inference]

mitotic spindle assembly

organelle assembly [inference]

non-membrane-bounded organelle assembly [inference]

spindle assembly [inference]

mitotic spindle assembly

cellular component assembly [inference]

organelle assembly [inference]

non-membrane-bounded organelle assembly [inference]

spindle assembly [inference]

mitotic spindle assembly

response to stimulus [inference]

response to stress [inference]

response to ischemia

Displaying entries **6 - 10** of 10 in total

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GO Term	Evidence Code	PMID
spindle pole centrosome	IDA	26195665
nucleus	IBA
centrosome	IDA	26195665
cytosol	TAS
cytoplasm	IDA	21195082 24075985

GO Hierarchy

cellular component

protein-containing complex [inference]

nuclear protein-containing complex [inference]

BRISC complex

cellular anatomical entity [inference]

microtubule organizing center [inference]

centrosome

spindle pole centrosome

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

supramolecular complex [inference]

supramolecular polymer [inference]

supramolecular fiber [inference]

polymeric cytoskeletal fiber [inference]

microtubule

microtubule end [inference]

microtubule minus-end

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein binding	IPI	19615732 26195665 32296183 33961781 37398436
microtubule binding	IBA IDA	26195665
polyubiquitin modification-dependent protein binding	IBA IDA	19261749

GO Hierarchy

molecular function

binding [inference]

protein binding

cytoskeletal protein binding [inference]

tubulin binding [inference]

microtubule binding

modification-dependent protein binding [inference]

polyubiquitin modification-dependent protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

uncharacterized protein

Functional Category

I: Lipid transport and metabolism
K: Transcription
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
microtubule binding
mitotic spindle assembly
polyubiquitin modification-dependent protein binding

Displaying 1 entry
InterPro
FAM175 family

Ortholog

Displaying entries **11 - 20** of 62 in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Ornithorhynchus anatinus	100077914		ORNAN17854
Sus scrofa	100158023		PIGXX08671
Taeniopygia guttata	100227300		TAEGU26669
Callithrix jacchus	100401674		CALJA07798
Pongo abelii	100449900	9601_0:00291e	PONAB01960
Ailuropoda melanoleuca	100471466		AILME05167
Anolis carolinensis	100558332		ANOCA04409
Nomascus leucogenys	100595794		NOMLE27210
Pan troglodytes	100611342	9598_0:002cb5	PANTR01764
Loxodonta africana	100671502		LOXAF04588